ultrasound-imaging-thoracic-abdominal-aorta-mice-to-determine

Ultrasound Imaging of the Thoracic and Abdominal Aorta in Mice to Determine Aneurysm Dimensions

Contemporary high-resolution ultrasound instruments have sufficient resolution to facilitate the measurement of mouse aortas. These instruments have been ...

University of Kentucky

Aortic Aneurysms.

Renin-Angiotensin System and Cardiovascular Functions.

Angiotensinogen (AGT) is the unique substrate of all angiotensin peptides. We review the recent preclinical research of AGT antisense oligonucleotides (ASOs), a rapidly evolving therapeutic approach. The scope of the research findings not only opens doors for potentially new therapeutics of hypertension and many other diseases, but also provides insights into understanding critical physiological and pathophysiological roles mediated by AGT.

Article	Year
Aortic Aneurysms. Arteriosclerosis, thrombosis, and vascular biology\| PubMed ID: 28539494	2017
Renin-Angiotensin System and Cardiovascular Functions. Arteriosclerosis, thrombosis, and vascular biology\| PubMed ID: 29950386	2018
Antisense oligonucleotides targeting angiotensinogen: insights from animal studies. Bioscience reports\| PubMed ID: 30530571	2019

Hong S. Lu

Biography

JoVE Journal Publications

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