a-high-throughput-assay-for-prediction-chemical-toxicity-automated

A High-throughput Assay for the Prediction of Chemical Toxicity by Automated Phenotypic Profiling of <em>Caenorhabditis elegans</em>

Applying toxicity testing of chemicals in higher order organisms, such as mice or rats, is time-consuming and expensive, due to their long lifespan and ...

Chinese Academy of Sciences, China

Traditional toxicological studies have relied heavily on various animal models to understand the effect of various compounds in a biological context. Considering the great cost, complexity and time involved in experiments using higher order organisms. Researchers have been exploring alternative models that avoid these disadvantages. One example of such a model is the nematode Caenorhabditis elegans. There are some advantages of C. elegans, such as small size, short life cycle, well defined genome, ease of maintenance and efficient reproduction.

Bo Xian

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