cloud-based-phrase-mining-analysis-user-defined-phrase-category

Cloud-Based Phrase Mining and Analysis of User-Defined Phrase-Category Association in Biomedical Publications

The rapid accumulation of biomedical textual data has far exceeded the human capacity of manual curation and analysis, necessitating novel text-mining ...

Miller Children's and Women's Hospital and Long Beach Memorial Hospital

Anomalous aortic origin of the right coronary artery: Embryology over genetics.

The purpose of this study is to report short- and long-term outcomes after congenital heart defect (CHD) interventions in patients with trisomy 13 or 18.

Long-Term Outcomes of Children With Trisomy 13 and 18 After Congenital Heart Disease Interventions.

The purpose of this study is to identify the impact of demographic, socioeconomic, and clinical factors on congenital heart surgery outcomes.

Healthcare Disparities in Outcomes of a Metropolitan Congenital Heart Surgery Center: The Effect of Clinical and Socioeconomic Factors.

Clinical case reports (CCRs) provide an important means of sharing clinical experiences about atypical disease phenotypes and new therapies. However, published case reports contain largely unstructured and heterogeneous clinical data, posing a challenge to mining relevant information. Current indexing approaches generally concern document-level features and have not been specifically designed for CCRs. To address this disparity, we developed a standardized metadata template and identified text corresponding to medical concepts within 3,100 curated CCRs spanning 15 disease groups and more than 750 reports of rare diseases. We also prepared a subset of metadata on reports on selected mitochondrial diseases and assigned ICD-10 diagnostic codes to each. The resulting resource, Metadata Acquired from Clinical Case Reports (MACCRs), contains text associated with high-level clinical concepts, including demographics, disease presentation, treatments, and outcomes for each report. Our template and MACCR set render CCRs more findable, accessible, interoperable, and reusable (FAIR) while serving as valuable resources for key user groups, including researchers, physician investigators, clinicians, data scientists, and those shaping government policies for clinical trials.

Article	Year
Anomalous aortic origin of the right coronary artery: Embryology over genetics. The Journal of thoracic and cardiovascular surgery\| PubMed ID: 25630857	2015
Long-Term Outcomes of Children With Trisomy 13 and 18 After Congenital Heart Disease Interventions. The Annals of thoracic surgery\| PubMed ID: 28456396	2017
Healthcare Disparities in Outcomes of a Metropolitan Congenital Heart Surgery Center: The Effect of Clinical and Socioeconomic Factors. Journal of racial and ethnic health disparities\| PubMed ID: 28849382	2018
A reference set of curated biomedical data and metadata from clinical case reports. Scientific data\| PubMed ID: 30457569	2018

Shaun P. Setty

Biography

JoVE Journal Publications

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