Lucy Liaw

Maine Medical Center Research Institute

Affiliated withMaine Medical Center Research Institute

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title Cited by 8	2019

Other Publications

Article	Year
Members of the Jagged/Notch gene families are expressed in injured arteries and regulate cell phenotype via alterations in cell matrix and cell-cell interaction. The American journal of pathology\| PubMed ID: 11549580	2001
Inactivation of the osteopontin gene enhances vascular calcification of matrix Gla protein-deficient mice: evidence for osteopontin as an inducible inhibitor of vascular calcification in viv... The Journal of experimental medicine\| PubMed ID: 12391016	2002
Osteopontin inhibits mineral deposition and promotes regression of ectopic calcification. The American journal of pathology\| PubMed ID: 12466120	2002
Notch activation suppresses fibroblast growth factor-dependent cellular transformation. The Journal of biological chemistry\| PubMed ID: 12598523	2003
Alterations of arterial physiology in osteopontin-null mice. Arteriosclerosis, thrombosis, and vascular biology\| PubMed ID: 12714436	2003
Improved analysis of the vascular response to arterial ligation using a multivariate approach. The American journal of pathology\| PubMed ID: 14695317	2004
The non-transmembrane form of Delta1, but not of Jagged1, induces normal migratory behavior accompanied by fibroblast growth factor receptor 1-dependent transformation. The Journal of biological chemistry\| PubMed ID: 14769803	2004
Expression and characterization of recombinant osteopontin peptides representing matrix metalloproteinase proteolytic fragments. Matrix biology : journal of the International Society for Matrix Biology\| PubMed ID: 15579312	2004
Collagen triple helix repeat containing 1, a novel secreted protein in injured and diseased arteries, inhibits collagen expression and promotes cell migration. Circulation research\| PubMed ID: 15618538	2005
Variable recombination efficiency in responder transgenes activated by Cre recombinase in the vasculature. Transgenic research\| PubMed ID: 16475014	2006
Selective expression of an aP2/Fatty Acid Binding Protein 4-Cre transgene in non-adipogenic tissues during embryonic development. Transgenic research\| PubMed ID: 16952017	2006
A novel mechanism of transcriptional repression of p27kip1 through Notch/HRT2 signaling in vascular smooth muscle cells. Thrombosis and haemostasis\| PubMed ID: 16953280	2006
Inhibition of breast cancer cell adhesion and bone metastasis by the extracellular adherence protein of Staphylococcus aureus. Biochemical and biophysical research communications\| PubMed ID: 17418809	2007
Notch2 signaling induces apoptosis and inhibits human MDA-MB-231 xenograft growth. The American journal of pathology\| PubMed ID: 17675579	2007
Widespread delta-like-1 expression in normal adult mouse tissue and injured endothelium is reflected by expression of the Dll1LacZ locus. Journal of vascular research\| PubMed ID: 17898542	2008
Development of fragment-specific osteopontin antibodies and ELISA for quantification in human metastatic breast cancer. BMC cancer\| PubMed ID: 18237408	2008
Hairy-related transcription factors inhibit Notch-induced smooth muscle alpha-actin expression by interfering with Notch intracellular domain/CBF-1 complex interaction with the CBF-1-binding... Circulation research\| PubMed ID: 18239137	2008
Overexpression of Spry1 in chondrocytes causes attenuated FGFR ubiquitination and sustained ERK activation resulting in chondrodysplasia. Developmental biology\| PubMed ID: 18582454	2008
Cardiovascular and hematopoietic defects associated with Notch1 activation in embryonic Tie2-expressing populations. Circulation research\| PubMed ID: 18617694	2008
Soluble forms of the Notch ligands Delta1 and Jagged1 promote in vivo tumorigenicity in NIH3T3 fibroblasts with distinct phenotypes. The American journal of pathology\| PubMed ID: 18688026	2008
Novel cross-talk between three cardiovascular regulators: thrombin cleavage fragment of Jagged1 induces fibroblast growth factor 1 expression and release. Molecular biology of the cell\| PubMed ID: 18784255	2008
Generation of iPS cells using defined factors linked via the self-cleaving 2A sequences in a single open reading frame. Cell research\| PubMed ID: 19238173	2009
Organ-specific lymphangiectasia, arrested lymphatic sprouting, and maturation defects resulting from gene-targeting of the PI3K regulatory isoforms p85alpha, p55alpha, and p50alpha. Developmental dynamics : an official publication of the American Association of Anatomists\| PubMed ID: 19705443	2009
Antigen-specific induction of osteopontin contributes to the chronification of allergic contact dermatitis. The American journal of pathology\| PubMed ID: 20008129	2010
Notch and transforming growth factor-beta (TGFbeta) signaling pathways cooperatively regulate vascular smooth muscle cell differentiation. The Journal of biological chemistry\| PubMed ID: 20368328	2010
Sprouty1 is a critical regulatory switch of mesenchymal stem cell lineage allocation. FASEB journal : official publication of the Federation of American Societies for Experimental Biology\| PubMed ID: 20410440	2010
Targeted genome modification in mice using zinc-finger nucleases. Genetics\| PubMed ID: 20628038	2010
The contribution of the Tie2+ lineage to primitive and definitive hematopoietic cells. Genesis (New York, N.Y. : 2000)\| PubMed ID: 20645309	2010
Cleavage of osteopontin by matrix metalloproteinase-12 modulates experimental autoimmune encephalomyelitis disease in C57BL/6 mice. The American journal of pathology\| PubMed ID: 20651245	2010
Human Sulfatase 2 inhibits in vivo tumor growth of MDA-MB-231 human breast cancer xenografts. BMC cancer\| PubMed ID: 20707913	2010
Follistatin-like 1 regulates renal IL-1Î² expression in cisplatin nephrotoxicity. American journal of physiology. Renal physiology\| PubMed ID: 20861081	2010
RhoA-mediated signaling in Notch-induced senescence-like growth arrest and endothelial barrier dysfunction. Arteriosclerosis, thrombosis, and vascular biology\| PubMed ID: 21273559	2011
Regulation of non-classical FGF1 release and FGF-dependent cell transformation by CBF1-mediated notch signaling. Journal of cellular physiology\| PubMed ID: 21302306	2011
Characterization of Pdgfrb-Cre transgenic mice reveals reduction of ROSA26 reporter activity in remodeling arteries. Genesis (New York, N.Y. : 2000)\| PubMed ID: 21557454	2011
The miR-143/145 cluster is a novel transcriptional target of Jagged-1/Notch signaling in vascular smooth muscle cells. The Journal of biological chemistry\| PubMed ID: 21685392	2011
Mechanisms of TGF-β-induced differentiation in human vascular smooth muscle cells. Journal of vascular research\| PubMed ID: 21832838	2011
Tissue-specific expression of Sprouty1 in mice protects against high-fat diet-induced fat accumulation, bone loss and metabolic dysfunction. The British journal of nutrition\| PubMed ID: 22142492	2012
Molecular pathways of notch signaling in vascular smooth muscle cells. Frontiers in physiology\| PubMed ID: 22509166	2012
Does treatment of split-thickness skin grafts with negative-pressure wound therapy improve tissue markers of wound healing in a porcine experimental model? The journal of trauma and acute care surgery\| PubMed ID: 22846954	2012
Notch1 activation in embryonic VE-cadherin populations selectively blocks hematopoietic stem cell generation and fetal liver hematopoiesis. Transgenic research\| PubMed ID: 22851140	2013
BMP9 regulates endoglin-dependent chemokine responses in endothelial cells. Blood\| PubMed ID: 23018639	2012
Cthrc1, a novel circulating hormone regulating metabolism. PloS one\| PubMed ID: 23056600	2012
Histone deacetylase activity selectively regulates notch-mediated smooth muscle differentiation in human vascular cells. Journal of the American Heart Association\| PubMed ID: 23130137	2012
Spry1 and Spry4 differentially regulate human aortic smooth muscle cell phenotype via Akt/FoxO/myocardin signaling. PloS one\| PubMed ID: 23554919	2013
Effect of soluble Jagged1-mediated inhibition of Notch signaling on proliferation and differentiation of an adipocyte progenitor cell model. Adipocyte\| PubMed ID: 23700510	2012
A receptor-specific function for Notch2 in mediating vascular smooth muscle cell growth arrest through cyclin-dependent kinase inhibitor 1B. Circulation research\| PubMed ID: 23965337	2013
Interactive 3D Analysis of Blood Vessel Trees and Collateral Vessel Volumes in Magnetic Resonance Angiograms in the Mouse Ischemic Hindlimb Model. The open medical imaging journal\| PubMed ID: 24563682	2013
Common features of microRNA target prediction tools. Frontiers in genetics\| PubMed ID: 24600468	2014
Inhibition of tumor-associated αvβ3 integrin regulates the angiogenic switch by enhancing expression of IGFBP-4 leading to reduced melanoma growth and angiogenesis in vivo. Angiogenesis\| PubMed ID: 25249331	2015
Notch signal integration in the vasculature during remodeling. Vascular pharmacology\| PubMed ID: 25464152	2014
Dynamic interplay between bone and multiple myeloma: emerging roles of the osteoblast. Bone\| PubMed ID: 25725265	2015
SLUG is a direct transcriptional repressor of PTEN tumor suppressor. The Prostate\| PubMed ID: 25728608	2015
Fibroblast growth factor signaling in the vasculature. Current atherosclerosis reports\| PubMed ID: 25813213	2015
BMP9 Crosstalk with the Hippo Pathway Regulates Endothelial Cell Matricellular and Chemokine Responses. PloS one\| PubMed ID: 25909848	2015
Cthrc1 controls adipose tissue formation, body composition, and physical activity. Obesity (Silver Spring, Md.)\| PubMed ID: 26148471	2015
Macrophage-derived osteopontin induces reactive astrocyte polarization and promotes re-establishment of the blood brain barrier after ischemic stroke. Glia\| PubMed ID: 26148976	2015
DLL4/Notch1 and BMP9 Interdependent Signaling Induces Human Endothelial Cell Quiescence via P27KIP1 and Thrombospondin-1. Arteriosclerosis, thrombosis, and vascular biology\| PubMed ID: 26471266	2015
Methods for Analyzing Tumor Angiogenesis in the Chick Chorioallantoic Membrane Model. Methods in molecular biology (Clifton, N.J.)\| PubMed ID: 26820962	2016
Lipid Profiling of In Vitro Cell Models of Adipogenic Differentiation: Relationships With Mouse Adipose Tissues. Journal of cellular biochemistry\| PubMed ID: 26910604	2016
Suppression of Spry4 enhances cancer stem cell properties of human MDA-MB-231 breast carcinoma cells. Cancer cell international\| PubMed ID: 26973433	2016
Suppression of Spry1 inhibits triple-negative breast cancer malignancy by decreasing EGF/EGFR mediated mesenchymal phenotype. Scientific reports\| PubMed ID: 26976794	2016
CRISPR/Cas9-Mediated Insertion of loxP Sites in the Mouse Dock7 Gene Provides an Effective Alternative to Use of Targeted Embryonic Stem Cells. G3 (Bethesda, Md.)\| PubMed ID: 27175020	2016
Effects of Treadmill Exercise on Advanced Osteoarthritis Pain in Rats. Arthritis & rheumatology (Hoboken, N.J.)\| PubMed ID: 28320059	2017
Exercise reverses pain-related weight asymmetry and differentially modulates trabecular bone microarchitecture in a rat model of osteoarthritis. Life sciences\| PubMed ID: 28504116	2017
Erratum to: Suppression of Spry4 enhances cancer stem cell properties of human MDA-MB-231 breast carcinoma cells. Cancer cell international\| PubMed ID: 28507453	2017
Loss of Spry1 attenuates vascular smooth muscle proliferation by impairing mitogen-mediated changes in cell cycle regulatory circuits. Journal of cellular biochemistry\| PubMed ID: 29105817	2018
Development of a 3D bone marrow adipose tissue model. Bone\| PubMed ID: 29366838	2019
Characterization of smooth muscle cells from human atherosclerotic lesions and their responses to Notch signaling. Laboratory investigation; a journal of technical methods and pathology\| PubMed ID: 29795127	2019
Notch2 and Proteomic Signatures in Mouse Neointimal Lesion Formation. Arteriosclerosis, thrombosis, and vascular biology\| PubMed ID: 29853569	2018
Rab27a Regulates Human Perivascular Adipose Progenitor Cell Differentiation. Cardiovascular drugs and therapy\| PubMed ID: 30105417	2018
A Renewable Source of Human Beige Adipocytes for Development of Therapies to Treat Metabolic Syndrome. Cell reports\| PubMed ID: 30540952	2018