Piotr Przanowski

Piotr Przanowski

Department of Biochemistry and Molecular Genetics, University of Virginia School of Medicine

Affiliated withUniversity of Virginia School of Medicine

Research Area

Biography

Piotr Przanowski is a Research Associate in Dr. Sanchita’s Bhatnagar’s laboratory in Department of Biochemistry and Molecular Genetics at University of Virginia (Charlottesville, USA). He received his bachelor and master of science degrees in biotechnology at University of Warsaw (Warsaw, Poland). In 2014 he obtained his PhD in “International PhD Program” at Nencki Institute of Experimental Biology (Warsaw, Poland). His thesis entitled “The role of the transcription factors Stat1 and Stat3 in the regulation of transcription jmjd3 and uba7, key mediators of inflammation” was conducted in Dr. Bozena Kaminska’s laboratory on transcriptional regulation of gene expression in gliomas and microglia. Piotr Przanowski received the Preludium Predoctoral Grant from the National Science Center (Poland) for his PhD research project. During his thesis work, he worked in laboratories of: Dr. Arkadiusz Piotrowski from Gdansk Medical University (Gdansk, Poland), Dr. Helmut Kettenmann from Max Delbruck Center (Berlin, Germany) and Dr. Jan Komorowski from Rudbeck Laboratory (Uppsala, Sweden).

During Dr. Przanowski’s training he developed a keen focus on research that encompasses interdisciplinary approaches to examine gene expression regulation in many different areas. As a post-doctoral fellow (2014-2015) in Dr. Bozena Kaminska’s laboratory in Nencki Institute of Experimental Biology (Warsaw, Poland) he conducted a project “Application of DNase I-seq to identify transcription factors participating in reprogramming of microglia into tumor promoting cells”. Upon completion he moved to Dr. Sanchita’s Bhatnagar’s laboratory at University of Virginia (Charlottesville, USA), where he currently works on two major, independent projects: silenced X chromosome reactivation and the role of oncogenic TRIM37 in breast cancer progression, using both in vitro and in vivo approaches. He also collaborates with Dr. Jogender Singh’s laboratory on the project about production of bispecific antibodies for ovarian cancer therapies.

His research program encompasses using mouse and human in vitro cell culture models and mice in vivo models to examine the regulation of gene expression and discover the phenotypic changes that affects diseases and cancer development.

Dr. Przanowski’s hobby is HEMA (Historical European Martial Arts). He compete on multiple national and international tournaments on longsword, rapier with dagger, saber and shortsword with buckler, receiving many medals.

Full list of published work is available at:

https://www.ncbi.nlm.nih.gov/pubmed/?term=przanowski+p

JoVE Journal Publications

ArticleTotal : 1
Year
A Non-random Mouse Model for Pharmacological Reactivation of Mecp2 on the Inactive X Chromosome
Publication title
2019

Other Publications

Article
Year
A Single-Agent Dual-Specificity Targeting of FOLR1 and DR5 as an Effective Strategy for Ovarian Cancer.

Cancer cell| PubMed ID: 30107179

2018
Pharmacological reactivation of inactive X-linked in cerebral cortical neurons of living mice.

Proceedings of the National Academy of Sciences of the United States of America| PubMed ID: 30012595

2018