Zhandong Liu

Zhandong Liu

Department of Pediatrics, Baylor College of Medicine

Affiliated withBaylor College of MedicineTexas Children's Hospital

Research Area

Biography

I did my undergraduate studies at the Nankai University in computer science, graduating in 2001. I received a M.S. in computer science from Wayne State University mentored by Dr. Sorin Draghici in 2004. I received a Ph.D. in genomics and computational biology from the University of Pennsylvania in 2010. The title of my dissertation was “The quantitative prediction of signal pathway activity through genome-wide gene expression data“, and Lewis A. Chodosh was my advisor. In 2010, I joined the Neurological Research Institute at the Baylor College of Medicine.

My research interests include topics in genomics, transcription regulation, disease genes prioritization, and machine learning. I often examine problems in these areas using methods and models from computer science, statistics, and related disciplines. Recently, I have been working on using Graphical Models to integrate multiple data types in the interest of advancing our understanding of neurological diseases.

JoVE Journal Publications

ArticleTotal : 1
Year
Navigating MARRVEL, a Web-Based Tool that Integrates Human Genomics and Model Organism Genetics Information
Publication title

Cited by 29

2019

Other Publications

Article
Year
Human-specific regulation of MeCP2 levels in fetal brains by microRNA miR-483-5p.

Genes & development| PubMed ID: 23431031

2013
2013
Expression and Functional Pathway Analysis of Nuclear Receptor NR2F2 in Ovarian Cancer.

The Journal of clinical endocrinology and metabolism| PubMed ID: 23690307

2013
2014
Combinatorial therapy discovery using mixed integer linear programming.

Bioinformatics (Oxford, England)| PubMed ID: 24463180

2014
2014
2013
2014
2014
2015
TCGA2STAT: simple TCGA data access for integrated statistical analysis in R.

Bioinformatics (Oxford, England)| PubMed ID: 26568634

2016
2015
2015
Crowdsourced estimation of cognitive decline and resilience in Alzheimer's disease.

Alzheimer's & dementia : the journal of the Alzheimer's Association| PubMed ID: 27079753

2016
2016
Graphical Models via Univariate Exponential Family Distributions.

Journal of machine learning research : JMLR| PubMed ID: 27570498

2015
2016
2016
2016
Transcriptional Regulation by ATOH1 and its Target SPDEF in the Intestine.

Cellular and molecular gastroenterology and hepatology| PubMed ID: 28174757

2017
2017
2017
2017
2017
2017
A Role for Progesterone-Regulated sFRP4 Expression in Uterine Leiomyomas.

The Journal of clinical endocrinology and metabolism| PubMed ID: 28637297

2017
2017
2017
2017
An ultra-fast and scalable quantification pipeline for transposable elements from next generation sequencing data.

Pacific Symposium on Biocomputing. Pacific Symposium on Biocomputing| PubMed ID: 29218879

2018
POU6f1 Mediates Neuropeptide-Dependent Plasticity in the Adult Brain.

The Journal of neuroscience : the official journal of the Society for Neuroscience| PubMed ID: 29305536

2018
Loss of Capicua alters early T cell development and predisposes mice to T cell lymphoblastic leukemia/lymphoma.

Proceedings of the National Academy of Sciences of the United States of America| PubMed ID: 29382756

2018
2018
2018
2018
2018
2018
2018
2018
2018
2018
2018
A Druggable Genome Screen Identifies Modifiers of α-Synuclein Levels via a Tiered Cross-Species Validation Approach.

The Journal of neuroscience : the official journal of the Society for Neuroscience| PubMed ID: 30249792

2018
2018
2018
2018
2019
2019
2019
2019
2019