Frank Maldarelli

The virology Core at the HIV Drug Resistance Program, NCI-Frederick

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title Cited by 10	2011

Other Publications

Article	Year
HIV-1 Fitness and Replication Capacity: What Are They and Can They Help in Patient Management? Current infectious disease reports\| PubMed ID: 12525294	2003
Innate immunity in human immunodeficiency virus infection: effect of viremia on natural killer cell function. The Journal of infectious diseases\| PubMed ID: 12660917	2003
New real-time reverse transcriptase-initiated PCR assay with single-copy sensitivity for human immunodeficiency virus type 1 RNA in plasma. Journal of clinical microbiology\| PubMed ID: 14532178	2003
Nonrandom HIV-1 infection and double infection via direct and cell-mediated pathways. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 14707263	2004
Changes in hepatitis C viral response after initiation of highly active antiretroviral therapy and control of HIV viremia in chronically co-infected individuals. HIV clinical trials\| PubMed ID: 15002084	2004
A proof-of-concept study of short-cycle intermittent antiretroviral therapy with a once-daily regimen of didanosine, lamivudine, and efavirenz for the treatment of chronic HIV infection. The Journal of infectious diseases\| PubMed ID: 15143462	2004
Prion Diseases: Update on Mad Cow Disease, Variant Creutzfeldt-Jakob Disease, and the Transmissible Spongiform Encephalopathies. Current infectious disease reports\| PubMed ID: 15265460	2004
Multiple, linked human immunodeficiency virus type 1 drug resistance mutations in treatment-experienced patients are missed by standard genotype analysis. Journal of clinical microbiology\| PubMed ID: 15635002	2005
Mechanism for nucleoside analog-mediated abrogation of HIV-1 replication: balance between RNase H activity and nucleotide excision. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 15684061	2005
Mechanisms of nonrandom human immunodeficiency virus type 1 infection and double infection: preference in virus entry is important but is not the sole factor. Journal of virology\| PubMed ID: 15767415	2005
Pravastatin does not have a consistent antiviral effect in chronically HIV-infected individuals on antiretroviral therapy. AIDS (London, England)\| PubMed ID: 15958846	2005
Tenofovir disoproxil fumarate and an optimized background regimen of antiretroviral agents as salvage therapy for pediatric HIV infection. Pediatrics\| PubMed ID: 16291735	2005
Selection and persistence of non-nucleoside reverse transcriptase inhibitor-resistant HIV-1 in patients starting and stopping non-nucleoside therapy. AIDS (London, England)\| PubMed ID: 16514300	2006
Consistent effects of TSG101 genetic variability on multiple outcomes of exposure to human immunodeficiency virus type 1. Journal of virology\| PubMed ID: 16809281	2006
Tenofovir disoproxil fumarate and an optimized background regimen of antiretroviral agents as salvage therapy: impact on bone mineral density in HIV-infected children. Pediatrics\| PubMed ID: 16923923	2006
Mutations in the connection domain of HIV-1 reverse transcriptase increase 3'-azido-3'-deoxythymidine resistance. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 17179211	2007
Enfuvirtide antiviral activity despite rebound viremia and resistance mutations: fitness tampering or a case of persistent braking on entering? The Journal of infectious diseases\| PubMed ID: 17205468	2007
ART suppresses plasma HIV-1 RNA to a stable set point predicted by pretherapy viremia. PLoS pathogens\| PubMed ID: 17411338	2007
Suppression of viremia and evolution of human immunodeficiency virus type 1 drug resistance in a macaque model for antiretroviral therapy. Journal of virology\| PubMed ID: 17855539	2007
Frequent polymorphism at drug resistance sites in HIV-1 protease and reverse transcriptase. AIDS (London, England)\| PubMed ID: 18301062	2008
Low-level viremia persists for at least 7 years in patients on suppressive antiretroviral therapy. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 18332425	2008
Variation in the major surface glycoprotein genes in Pneumocystis jirovecii. The Journal of infectious diseases\| PubMed ID: 18627244	2008
Efavirenz induces CYP2B6-mediated hydroxylation of bupropion in healthy subjects. Journal of acquired immune deficiency syndromes (1999)\| PubMed ID: 18989234	2008
Iatrogenic Cushing syndrome after epidural triamcinolone injections in an HIV type 1-infected patient receiving therapy with ritonavir-lopinavir. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America\| PubMed ID: 18991509	2008
Lytic granule loading of CD8+ T cells is required for HIV-infected cell elimination associated with immune control. Immunity\| PubMed ID: 19062316	2008
Inferiority of IL-2 alone versus IL-2 with HAART in maintaining CD4 T cell counts during HAART interruption: a randomized controlled trial. AIDS (London, England)\| PubMed ID: 19098490	2009
Regimen simplification to atazanavir-ritonavir alone as maintenance antiretroviral therapy: final 48-week clinical and virologic outcomes. The Journal of infectious diseases\| PubMed ID: 19191590	2009
Evaluation of the pathogenesis of decreasing CD4(+) T cell counts in human immunodeficiency virus type 1-infected patients receiving successfully suppressive antiretroviral therapy. The Journal of infectious diseases\| PubMed ID: 19432547	2009
Subtype-specific differences in the human immunodeficiency virus type 1 reverse transcriptase connection subdomain of CRF01_AE are associated with higher levels of resistance to 3'-azido-3'-... Journal of virology\| PubMed ID: 19553318	2009
RT-SHIV subpopulation dynamics in infected macaques during anti-HIV therapy. Retrovirology\| PubMed ID: 19889213	2009
Optimization of allele-specific PCR using patient-specific HIV consensus sequences for primer design. Journal of virological methods\| PubMed ID: 19948190	2010
Comparison of standard PCR/cloning to single genome sequencing for analysis of HIV-1 populations. Journal of virological methods\| PubMed ID: 20451557	2010
Patterns of Human Immunodeficiency Virus type 1 recombination ex vivo provide evidence for coadaptation of distant sites, resulting in purifying selection for intersubtype recombinants durin... Journal of virology\| PubMed ID: 20504919	2010
HIV-1 continues to replicate and evolve in patients with natural control of HIV infection. Journal of virology\| PubMed ID: 20926564	2010
Current status of xenotropic murine leukemia virus-related retrovirus in chronic fatigue syndrome and prostate cancer: reach for a scorecard, not a prescription pad. The Journal of infectious diseases\| PubMed ID: 20936981	2010
XMRV: a new virus in prostate cancer? Cancer research\| PubMed ID: 20966126	2010
Characterization of the meiosis-specific recombinase Dmc1 of pneumocystis. The Journal of infectious diseases\| PubMed ID: 21050123	2010
Genetic diversity of simian immunodeficiency virus encoding HIV-1 reverse transcriptase persists in macaques despite antiretroviral therapy. Journal of virology\| PubMed ID: 21084490	2011
Targeting viral reservoirs: ability of antiretroviral therapy to stop viral replication. Current opinion in HIV and AIDS\| PubMed ID: 21228755	2011
CD4 and CD8 T cell immune activation during chronic HIV infection: roles of homeostasis, HIV, type I IFN, and IL-7. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 21257970	2011
High dose atorvastatin decreases cellular markers of immune activation without affecting HIV-1 RNA levels: results of a double-blind randomized placebo controlled clinical trial. The Journal of infectious diseases\| PubMed ID: 21325137	2011
Estimate of effective recombination rate and average selection coefficient for HIV in chronic infection. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 21436045	2011
Transmitted raltegravir resistance in an HIV-1 CRF_AG-infected patient. Antiviral therapy\| PubMed ID: 21447876	2011
Majority of CD4+ T cells from peripheral blood of HIV-1-infected individuals contain only one HIV DNA molecule. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 21690402	2011
Genotypic resistance at viral rebound among patients who received lopinavir/ritonavir-based or efavirenz-based first antiretroviral therapy in South Africa. Journal of acquired immune deficiency syndromes (1999)\| PubMed ID: 21694608	2011
Clinical management of HIV drug resistance. Viruses\| PubMed ID: 21994737	2011
Short-course raltegravir intensification does not increase 2 long terminal repeat episomal HIV-1 DNA in patients on effective antiretroviral therapy. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America\| PubMed ID: 22016501	2012
Short-course Combivir after single-dose nevirapine reduces but does not eliminate the emergence of nevirapine resistance in women. Antiviral therapy\| PubMed ID: 22293443	2011