Howard Crawford

Department of Molecular and Cellular Physiology, University of Michigan

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title Cited by 15	2019

Other Publications

Article	Year
ADAM10 is essential for Notch2-dependent marginal zone B cell development and CD23 cleavage in vivo. The Journal of experimental medicine\| PubMed ID: 20156974	2010
Constitutive α- and β-secretase cleavages of the amyloid precursor protein are partially coupled in neurons, but not in frequently used cell lines. Neurobiology of disease\| PubMed ID: 22940630	2013
Distinct TCR signaling pathways drive proliferation and cytokine production in T cells. Nature immunology\| PubMed ID: 23377202	2013
Identification and manipulation of biliary metaplasia in pancreatic tumors. Gastroenterology\| PubMed ID: 23999170	2014
ADAM10 regulates Notch function in intestinal stem cells of mice. Gastroenterology\| PubMed ID: 25038433	2014
Somatostatin receptor subtype 2 as pancreatic tumorigenesis suppressor: identification of a new targetable signaling node. Gastroenterology\| PubMed ID: 25921374	2015
Oligodendrocyte Regeneration and CNS Remyelination Require TACE/ADAM17. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 26338334	2015
Ductal pancreatic cancer modeling and drug screening using human pluripotent stem cell- and patient-derived tumor organoids. Nature medicine\| PubMed ID: 26501191	2015
Ablation of sensory neurons in a genetic model of pancreatic ductal adenocarcinoma slows initiation and progression of cancer. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 26929329	2016
Mutant KRas-Induced Mitochondrial Oxidative Stress in Acinar Cells Upregulates EGFR Signaling to Drive Formation of Pancreatic Precancerous Lesions. Cell reports\| PubMed ID: 26947075	2016
NRF2 Promotes Tumor Maintenance by Modulating mRNA Translation in Pancreatic Cancer. Cell\| PubMed ID: 27477511	2016
PDX1 dynamically regulates pancreatic ductal adenocarcinoma initiation and maintenance. Genes & development\| PubMed ID: 28087712	2016
Mitogen-activated Protein Kinase Kinase Activity Maintains Acinar-to-Ductal Metaplasia and Is Required for Organ Regeneration in Pancreatitis. Cellular and molecular gastroenterology and hepatology\| PubMed ID: 28090569	2017
Epithelial-Myeloid cell crosstalk regulates acinar cell plasticity and pancreatic remodeling in mice. eLife\| PubMed ID: 28980940	2017
MYC regulates ductal-neuroendocrine lineage plasticity in pancreatic ductal adenocarcinoma associated with poor outcome and chemoresistance. Nature communications\| PubMed ID: 29170413	2017
HNF1A is a novel oncogene that regulates human pancreatic cancer stem cell properties. eLife\| PubMed ID: 30074477	2018
STAT3 is a master regulator of epithelial identity and KRAS-driven tumorigenesis. Genes & development\| PubMed ID: 30135074	2018
Epithelial-Stromal Interactions in Pancreatic Cancer. Annual review of physiology\| PubMed ID: 30418798	2019
Spatial and phenotypic immune profiling of metastatic colon cancer. JCI insight\| PubMed ID: 30429368	2018
The Loss of ATRX Increases Susceptibility to Pancreatic Injury and Oncogenic KRAS in Female But Not Male Mice. Cellular and molecular gastroenterology and hepatology\| PubMed ID: 30510993	2019
Signaling Networks That Control Cellular Plasticity in Pancreatic Tumorigenesis, Progression, and Metastasis. Gastroenterology\| PubMed ID: 30716326	2019
Macrophage-Released Pyrimidines Inhibit Gemcitabine Therapy in Pancreatic Cancer. Cell metabolism\| PubMed ID: 30827862	2019
ATDC is required for the initiation of KRAS-induced pancreatic tumorigenesis. Genes & development\| PubMed ID: 31048544	2019
Myeloid Cell-Derived HB-EGF Drives Tissue Recovery After Pancreatitis. Cellular and molecular gastroenterology and hepatology\| PubMed ID: 31125624	2019
Hiding in plain sight. Science (New York, N.Y.)\| PubMed ID: 31221844	2019