Chi-Keung Cheng

Blood Cancer Cytogenetics and Genomics Laboratory, The Chinese University of Hong Kong

Affiliated withThe Chinese University of Hong Kong

Research Area

Biography

Dr. Cheng received his undergraduate degree (first class honors) and M.Phil. from the University of Hong Kong, and a Ph.D. from the University of British Columbia, Canada. He is currently in charge of the Molecular Hematology services in the Prince of Wales Hospital, Hong Kong. Dr. Cheng is also an Adjunct Associate Professor of the Department of Anatomical & Cellular Pathology, The Chinese University of Hong Kong. His main research focuses on the identification and molecular characterization of novel genetic/epigenetic aberrations in acute myeloid leukemia, a lethal blood cancer in adults and children. His work has been published in Blood, Haematologica and Molecular Cancer.

JoVE Journal Publications

ArticleTotal : 1	Year
Publication title Cited by 3	2019

Other Publications

Article	Year
Transcriptional repression of the RUNX3/AML2 gene by the t(8;21) and inv(16) fusion proteins in acute myeloid leukemia. Blood\| PubMed ID: 18663147	2008
Secreted-frizzled related protein 1 is a transcriptional repression target of the t(8;21) fusion protein in acute myeloid leukemia. Blood\| PubMed ID: 22031861	2011
Platelet factor 4 induces cell apoptosis by inhibition of STAT3 via up-regulation of SOCS3 expression in multiple myeloma. Haematologica\| PubMed ID: 22929979	2013
A polymorphism in the 3'-untranslated region of the NPM1 gene causes illegitimate regulation by microRNA-337-5p and correlates with adverse outcome in acute myeloid leukemia. Haematologica\| PubMed ID: 23065518	2013
Draft genome sequence of Salmonella enterica serovar Typhimurium ST1660/06, a multidrug-resistant clinical strain isolated from a diarrheic patient. Journal of bacteriology\| PubMed ID: 23105062	2012
5'-Serial Analysis of Gene Expression studies reveal a transcriptomic switch during fruiting body development in Coprinopsis cinerea. BMC genomics\| PubMed ID: 23514374	2013
Minimal residual disease-based risk stratification in Chinese childhood acute lymphoblastic leukemia by flow cytometry and plasma DNA quantitative polymerase chain reaction. PloS one\| PubMed ID: 23936021	2013
Genome Sequences of Salmonella enterica Serotype Typhimurium Blood Clinical Isolate ST4848/06 and Stool Isolate ST1489/06. Genome announcements\| PubMed ID: 24136846	2013
Congenital sideroblastic anaemia with a novel frameshift mutation in SLC25A38. Journal of clinical pathology\| PubMed ID: 25512395	2015
Next generation genome sequencing reveals phylogenetic clades with different level of virulence among Salmonella Typhimurium clinical human isolates in Hong Kong. BMC genomics\| PubMed ID: 26370680	2015
Helicase-like transcription factor is a RUNX1 target whose downregulation promotes genomic instability and correlates with complex cytogenetic features in acute myeloid leukemia. Haematologica\| PubMed ID: 26802049	2016
FNDC3B is another novel partner fused to RARA in the t(3;17)(q26;q21) variant of acute promyelocytic leukemia. Blood\| PubMed ID: 28314734	2017
Distinctive regional-specific PROS1 mutation spectrum in Southern China. Journal of thrombosis and thrombolysis\| PubMed ID: 29748776	2018
Prevalence and Clinicopathologic Significance of BRAF V600E Mutation in Chinese Multiple Myeloma Patients. Clinical lymphoma, myeloma & leukemia\| PubMed ID: 29807803	2018
RUNX1 upregulation via disruption of long-range transcriptional control by a novel t(5;21)(q13;q22) translocation in acute myeloid leukemia. Molecular cancer\| PubMed ID: 30157851	2018
Discovery of microRNA-like RNAs during early fruiting body development in the model mushroom Coprinopsis cinerea. PloS one\| PubMed ID: 30231028	2018