Chi Li

Department of Pharmacology and Toxicology, University of Louisville

Research Area

Biography

Chia-Wei Liou is a Ph.D. student in the Institute of Basic Medical Sciences, College of Medicine, National Cheng Kung University in Taiwan. He received his Master degree in the Department of Physiology, College of Medicine, National Cheng Kung University (NCKU).

Chia-Wei focus on the effects of high-dietary sugar on renal function and using Drosophila as an experimental model. After he joined Dr. Wei-Li Wu's lab in NCKU, he started to be trained with the techniques in neuroscience and received the knowledge of neuroscience and gut-brain axis. His thesis during Ph.D. program is to study the effects of gut metabolites in the brain to regulate emotional behaviors in mice.

JoVE Journal Publications

ArticleTotal : 2	Year
Publication title Cited by 12	2021
Publication title	2025

Other Publications

Article	Year
Apoptosis regulation by Bcl-x(L) modulation of mammalian inositol 1,4,5-trisphosphate receptor channel isoform gating. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 17636122	2007
The Bax carboxy-terminal hydrophobic helix does not determine organelle-specific targeting but is essential for maintaining Bax in an inactive state and for stable mitochondrial membrane ins... Apoptosis : an international journal on programmed cell death\| PubMed ID: 19809877	2010
Actinomycin D synergistically enhances the efficacy of the BH3 mimetic ABT-737 by downregulating Mcl-1 expression. Cancer biology & therapy\| PubMed ID: 20818182	2010
ER stress modulates cellular metabolism. The Biochemical journal\| PubMed ID: 21241252	2011
Distinct roles of mitochondria- and ER-localized Bcl-xL in apoptosis resistance and Ca2+ homeostasis. Molecular biology of the cell\| PubMed ID: 22573883	2012
Haem oxygenase-1 overexpression alters intracellular iron distribution. The Biochemical journal\| PubMed ID: 22989377	2013
Titanium dioxide (TiO2) nanoparticles preferentially induce cell death in transformed cells in a Bak/Bax-independent fashion. PloS one\| PubMed ID: 23185639	2012
An interaction between Bcl-xL and the voltage-dependent anion channel (VDAC) promotes mitochondrial Ca2+ uptake. The Journal of biological chemistry\| PubMed ID: 23720737	2013
Noxa couples lysosomal membrane permeabilization and apoptosis during oxidative stress. Free radical biology & medicine\| PubMed ID: 23770082	2013
Prediction of peptide drift time in ion mobility mass spectrometry from sequence-based features. BMC bioinformatics\| PubMed ID: 23815343	2013
Activation of the proapoptotic Bcl-2 protein Bax by a small molecule induces tumor cell apoptosis. Molecular and cellular biology\| PubMed ID: 24421393	2014
Pseudomonas aeruginosa homoserine lactone triggers apoptosis and Bak/Bax-independent release of mitochondrial cytochrome C in fibroblasts. Cellular microbiology\| PubMed ID: 24438098	2014
Paraoxonase 2 serves a proapopotic function in mouse and human cells in response to the Pseudomonas aeruginosa quorum-sensing molecule N-(3-Oxododecanoyl)-homoserine lactone. The Journal of biological chemistry\| PubMed ID: 25627690	2015
Proapoptotic activities of protein disulfide isomerase (PDI) and PDIA3 protein, a role of the Bcl-2 protein Bak. The Journal of biological chemistry\| PubMed ID: 25697356	2015
Structural transition in Bcl-xL and its potential association with mitochondrial calcium ion transport. Scientific reports\| PubMed ID: 26023881	2015
Increased Mitochondrial Activity in Anthrax-Induced Cell Death. Journal of cell death\| PubMed ID: 26124679	2009
How Heme Oxygenase-1 Prevents Heme-Induced Cell Death. PloS one\| PubMed ID: 26270345	2015
Dissecting the leukemogenic potency of BCLxl. Journal of leukemia (Los Angeles, Calif.)\| PubMed ID: 26636115	2014
N-(3-oxo-acyl) homoserine lactone inhibits tumor growth independent of Bcl-2 proteins. Oncotarget\| PubMed ID: 26758417	2016
Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition). Autophagy\| PubMed ID: 26799652	2016
N-(3-Oxo-acyl)-homoserine lactone induces apoptosis primarily through a mitochondrial pathway in fibroblasts. Cellular microbiology\| PubMed ID: 28876505	2018
Vaccination with induced pluripotent stem cells confers protection against cancer. Stem cell investigation\| PubMed ID: 30148156	2018
N-(3-oxo-acyl) homoserine lactone induced germ cell apoptosis and suppressed the over-activated RAS/MAPK tumorigenesis via mitochondrial-dependent ROS in C. elegans. Apoptosis : an international journal on programmed cell death\| PubMed ID: 30171376	2018
Exosomes from GM-CSF expressing embryonic stem cells are an effective prophylactic vaccine for cancer prevention. Oncoimmunology\| PubMed ID: 30723593	2019
Regulatory Role of Immune Cell-Derived Extracellular Vesicles in Cancer: The Message Is in the Envelope. Frontiers in immunology\| PubMed ID: 32765528	2020
Cancer Vaccines: Promising Therapeutics or an Unattainable Dream. Vaccines\| PubMed ID: 34207062	2021
PON2 mediates mitochondrial dysfunction in tracheal epithelial cells in response to a quorum sensing molecule N-(-3-oxododecanoyl)-l-homoserine lactone. The Biochemical journal\| PubMed ID: 36094147	2022
Exosome-based cancer vaccine for prevention of lung cancer. Stem cell investigation\| PubMed ID: 36742283	2023
Zeb1 facilitates corneal epithelial wound healing by maintaining corneal epithelial cell viability and mobility. Communications biology\| PubMed ID: 37081200	2023
Paraoxonase 2 (PON2) plays a limited role in murine lung tumorigenesis. Scientific reports\| PubMed ID: 37337025	2023
Monocytic MDSCs exhibit superior immune suppression via adenosine and depletion of adenosine improves efficacy of immunotherapy. Science advances\| PubMed ID: 37390211	2023
Short chain fatty acids inhibit corneal inflammatory responses to TLR ligands via the ocular G-protein coupled receptor 43. The ocular surface\| PubMed ID: 38224777	2024
The efficacy of an embryonic stem cell-based vaccine for lung cancer prevention depends on the undifferentiated state of the stem cells. Scientific reports\| PubMed ID: 39739089	2024
Biodistribution studies of Zr-Labeled stem cell-derived exosomes using PET imaging. Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine\| PubMed ID: 40532508	2025