in-situ-monitoring-transiently-formed-molecular-chaperone-assemblies

In Situ Monitoring of Transiently Formed Molecular Chaperone Assemblies in Bacteria, Yeast, and Human Cells

J-domain proteins (JDPs) form the largest and the most diverse co-chaperone family in eukaryotic cells. Recent findings show that specific members of the ...

University of Colombo

Accurate anatomical landmarks to locate the thoracodorsal nerve are important in axillary clearance surgery.

An improved technical trick for identification of the thoracodorsal nerve during axillary clearance surgery: a cadaveric dissection study.

The marginal mandibular branch of the facial nerve is vulnerable to iatrogenic injuries during surgeries involving the submandibular region. This leads to significant post-operative morbidity. Studies assessing accurate anatomical landmarks of the marginal mandibular branch are sparse in South Asian countries. Present study was conducted to assess the relationship between the marginal mandibular branch and the inferior border of the body of mandible.

Preserving the marginal mandibular branch of the facial nerve during submandibular region surgery: a cadaveric safety study.

To identify the different perceptions on informed surgical consent in a group of Sri Lankan patients.

Are predominantly western standards and expectations of informed consent in surgery applicable to all? A qualitative study in a tertiary care hospital in Sri Lanka.

The purpose of this study was to identify surface anatomy of digital nerves in relation to the pigmented border of digits. Three-hundred and sixty digital nerves in 36 preserved adult cadaveric hands were dissected under magnification. The digital nerves were constantly located anterior to the pigmented border. The median curvilinear distance along the skin from the pigmented border to the digital nerves of the index, middle, ring and little fingers was 1.4 mm. In the thumb, this distance was 2.4 and 3.7 mm on the radial and ulnar sides, respectively. The digital nerve was located 2.4 mm deep to the skin in all fingers. The median angle to the nerve from the skin at the pigmented border was 30°. These dimensions differed in the thumb compared with the rest of the fingers. We conclude that the pigmented border of digits is a reliable anatomical landmark to locate digital nerves.

Pigmented border as a new surface landmark for digital nerve blocks: a cross sectional anatomical study.

: A primary objective in stroke rehabilitation is to restore functional balance, in order to reduce falls. : To identify the efficacy and safety of wobble board exercises when combined with conventional physiotherapy, in improving balance in hemiplegic patients following ischemic strokes. : A block-randomized, controlled, observer blinded, superiority trial was conducted on ambulatory hemiplegic patients following ischemic strokes of middle cerebral artery territory. Subjects in the control group received a conventional physiotherapy regime. Subjects in the intervention group received training on a wobble board combined with conventional physiotherapy. Main Outcome measures were the improvement of Four-Square Step Test (FSST) and the Berg Balance Scale (BBS), both of which assess functional balance at the end of 6 weeks. : Thirty patients were randomly assigned for intervention (n = 15) and control (n = 15) groups. One patient dropped out from the study, leaving 29 eligible for the analysis. Intervention and control groups were comparable in sociodemographic characteristics and pre-test scores of balance. A repeated-measures MANOVA showed a significant difference in improvement of balance between the two study groups after 6 weeks [F(1,28) = 32.6, = .000; Wilk's lambda = .46]. The improvement of mean score of balance in interventional group was greater than in the control group [BBS:9.5 (intervention group),5.5 (control group); FSST:3.9 (intervention group),1.7 (control group)]. There were no injuries in both groups. : Wobble board exercises, when combined with the conventional physiotherapy, are safe and effective in restoring functional balance in patients with hemiplegia following ischemic strokes.

Article	Year
An improved technical trick for identification of the thoracodorsal nerve during axillary clearance surgery: a cadaveric dissection study. Patient safety in surgery\| PubMed ID: 29983745	2018
Preserving the marginal mandibular branch of the facial nerve during submandibular region surgery: a cadaveric safety study. Patient safety in surgery\| PubMed ID: 30159033	2018
Are predominantly western standards and expectations of informed consent in surgery applicable to all? A qualitative study in a tertiary care hospital in Sri Lanka. BMJ open\| PubMed ID: 30813111	2019
Pigmented border as a new surface landmark for digital nerve blocks: a cross sectional anatomical study. The Journal of hand surgery, European volume\| PubMed ID: 31042104	2019
Improving balance with wobble board exercises in stroke patients: single-blind, randomized clinical trial. Topics in stroke rehabilitation\| PubMed ID: 31348727	2019

Yasith Mathangasinghe

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