Eric Jenkinson

MRC Center for Immune Regulation, University of Birmingham

Research Area

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JoVE Journal Publications

ArticleTotal : 2	Year
Publication title Cited by 22	2008
Publication title Cited by 8	2008

Other Publications

Article	Year
Induction of thymocyte positive selection does not convey immediate resistance to negative selection. Immunology\| PubMed ID: 11872091	2002
Entry into the thymic microenvironment triggers Notch activation in the earliest migrant T cell progenitors. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 12538689	2003
Microenvironmental regulation of Notch signalling in T cell development. Seminars in immunology\| PubMed ID: 12681945	2003
Con A activates an Akt/PKB dependent survival mechanism to modulate TCR induced cell death in double positive thymocytes. Molecular immunology\| PubMed ID: 12749908	2003
Cutting edge: a chemical genetic system for the analysis of kinases regulating T cell development. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 12847211	2003
Differential requirement for mesenchyme in the proliferation and maturation of thymic epithelial progenitors. The Journal of experimental medicine\| PubMed ID: 12860931	2003
Thymic epithelial cells provide WNT signals to developing thymocytes. European journal of immunology\| PubMed ID: 12884861	2003
Progression through key stages of haemopoiesis is dependent on distinct threshold levels of c-Myb. The EMBO journal\| PubMed ID: 12941699	2003
Modeling TCR signaling complex formation in positive selection. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 12960303	2003
A stroma-derived defect in NF-kappaB2-/- mice causes impaired lymph node development and lymphocyte recruitment. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 15294939	2004
T/B lineage choice occurs prior to intrathymic Notch signaling. Blood\| PubMed ID: 15845899	2005
OX40 ligand and CD30 ligand are expressed on adult but not neonatal CD4+CD3- inducer cells: evidence that IL-7 signals regulate CD30 ligand but not OX40 ligand expression. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 15905508	2005
Development of functional thymic epithelial cells occurs independently of lymphostromal interactions. Mechanisms of development\| PubMed ID: 16274965	2005
Establishment and functioning of intrathymic microenvironments. Immunological reviews\| PubMed ID: 16448531	2006
Clonal analysis reveals a common progenitor for thymic cortical and medullary epithelium. Nature\| PubMed ID: 16791197	2006
The thymus and T-cell commitment: the right niche for Notch? Nature reviews. Immunology\| PubMed ID: 16799474	2006
Overexpression of ICAT highlights a role for catenin-mediated canonical Wnt signalling in early T cell development. European journal of immunology\| PubMed ID: 16897815	2006
Neonatal and adult CD4+ CD3- cells share similar gene expression profile, and neonatal cells up-regulate OX40 ligand in response to TL1A (TNFSF15). Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 16920944	2006
PDGFRalpha-expressing mesenchyme regulates thymus growth and the availability of intrathymic niches. Blood\| PubMed ID: 17008543	2007
Function of CD4+CD3- cells in relation to B- and T-zone stroma in spleen. Blood\| PubMed ID: 17018858	2007
RANK signals from CD4(+)3(-) inducer cells regulate development of Aire-expressing epithelial cells in the thymic medulla. The Journal of experimental medicine\| PubMed ID: 17502664	2007
Lymphotoxin a-dependent and -independent signals regulate stromal organizer cell homeostasis during lymph node organogenesis. Blood\| PubMed ID: 17526859	2007
Chemokine receptor expression defines heterogeneity in the earliest thymic migrants. European journal of immunology\| PubMed ID: 17578846	2007
CD248/Endosialin is dynamically expressed on a subset of stromal cells during lymphoid tissue development, splenic remodeling and repair. FEBS letters\| PubMed ID: 17628549	2007
EphrinB1-EphB signaling regulates thymocyte-epithelium interactions involved in functional T cell development. European journal of immunology\| PubMed ID: 17668899	2007
Redefining epithelial progenitor potential in the developing thymus. European journal of immunology\| PubMed ID: 17694573	2007
Investigating central tolerance with reaggregate thymus organ cultures. Methods in molecular biology (Clifton, N.J.)\| PubMed ID: 17876094	2007
AIRE's CARD revealed, a new structure for central tolerance provokes transcriptional plasticity. The Journal of biological chemistry\| PubMed ID: 17974569	2008
Generating intrathymic microenvironments to establish T-cell tolerance. Nature reviews. Immunology\| PubMed ID: 17992179	2007
Role of CD30 in B/T segregation in the spleen. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 18025198	2007
Heterogeneity of lymphoid tissue inducer cell populations present in embryonic and adult mouse lymphoid tissues. Immunology\| PubMed ID: 18205791	2008
Sequential phases in the development of Aire-expressing medullary thymic epithelial cells involve distinct cellular input. European journal of immunology\| PubMed ID: 18350550	2008
TSCOT+ thymic epithelial cell-mediated sensitive CD4 tolerance by direct presentation. PLoS biology\| PubMed ID: 18684012	2008
An epithelial progenitor pool regulates thymus growth. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 18941199	2008
Bringing the thymus to the bench. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 19017928	2008
Transplantation of embryonic spleen tissue reveals a role for adult non-lymphoid cells in initiating lymphoid tissue organization. European journal of immunology\| PubMed ID: 19089813	2009
Checkpoints in the development of thymic cortical epithelial cells. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 19109143	2009
A roadmap for thymic epithelial cell development. European journal of immunology\| PubMed ID: 19582736	2009
Absence of thymus crosstalk in the fetus does not preclude hematopoietic induction of a functional thymus in the adult. European journal of immunology\| PubMed ID: 19662637	2009
Splenic stromal cells mediate IL-7 independent adult lymphoid tissue inducer cell survival. European journal of immunology\| PubMed ID: 19950181	2010
Wnt4 and LAP2alpha as pacemakers of thymic epithelial senescence. PloS one\| PubMed ID: 20502698	2010
Lymphotoxin signals from positively selected thymocytes regulate the terminal differentiation of medullary thymic epithelial cells. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 20861360	2010
Fetal thymus organ culture. CSH protocols\| PubMed ID: 21357146	2007
Clonal analysis reveals uniformity in the molecular profile and lineage potential of CCR9(+) and CCR9(-) thymus-settling progenitors. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 21421850	2011
Wnt-4 protects thymic epithelial cells against dexamethasone-induced senescence. Rejuvenation research\| PubMed ID: 21453014	2011
Multiple suppression pathways of canonical Wnt signalling control thymic epithelial senescence. Mechanisms of ageing and development\| PubMed ID: 21549744	2011
A novel method to allow non-invasive, longitudinal imaging of the murine immune system in vivo. Blood\| PubMed ID: 22271449	2012