Jack Wetzels

Radboud Institute for Health Sciences, Radboud university medical center

Affiliated withRadboud university medical center

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title	2020

Other Publications

Article	Year
Nurse practitioner care improves renal outcome in patients with CKD. Journal of the American Society of Nephrology : JASN\| PubMed ID: 24158983	2014
Long-term treatment with tenofovir: prevalence of kidney tubular dysfunction and its association with tenofovir plasma concentration. Antiviral therapy\| PubMed ID: 24584104	2014
Phospholipase A2 receptor antibodies in membranous nephropathy: unresolved issues. Journal of the American Society of Nephrology : JASN\| PubMed ID: 24610931	2014
Glucose specifically regulates TRPC6 expression in the podocyte in an AngII-dependent manner. The American journal of pathology\| PubMed ID: 24731445	2014
TRPC6 single nucleotide polymorphisms and progression of idiopathic membranous nephropathy. PloS one\| PubMed ID: 25019165	2014
Novel aspects of atypical haemolytic uraemic syndrome and the role of eculizumab. Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association\| PubMed ID: 25165180	2014
Permeability factors in idiopathic nephrotic syndrome: historical perspectives and lessons for the future. Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association\| PubMed ID: 25416821	2014
Urinary biomarkers after donor nephrectomy. Transplant international : official journal of the European Society for Organ Transplantation\| PubMed ID: 25581388	2015
Impact of fractional phosphate excretion on the relation of FGF23 with outcome in CKD patients. Journal of nephrology\| PubMed ID: 25700931	2015
Individualizing pharmacotherapy in patients with renal impairment: the validity of the Modification of Diet in Renal Disease formula in specific patient populations with a glomerular filtrat... PloS one\| PubMed ID: 25741695	2015
Kidney injury molecule-1 and neutrophil gelatinase-associated lipocalin as prognostic markers in idiopathic membranous nephropathy. Annals of clinical biochemistry\| PubMed ID: 25762211	2016
Serum anti-PLA2R antibodies can be initially absent in idiopathic membranous nephropathy: seroconversion after prolonged follow-up. Kidney international\| PubMed ID: 26024039	2015
Sensitive, reliable and easy-performed laboratory monitoring of eculizumab therapy in atypical hemolytic uremic syndrome. Clinical immunology (Orlando, Fla.)\| PubMed ID: 26111482	2015
Therapy: Maintenance of steroid-free remission in nephrotic syndrome. Nature reviews. Nephrology\| PubMed ID: 26195145	2015
Proximal tubular efflux transporters involved in renal excretion of p-cresyl sulfate and p-cresyl glucuronide: Implications for chronic kidney disease pathophysiology. Toxicology in vitro : an international journal published in association with BIBRA\| PubMed ID: 26216510	2015
Estimation of total kidney volume in autosomal dominant polycystic kidney disease. American journal of kidney diseases : the official journal of the National Kidney Foundation\| PubMed ID: 26235803	2015
Rituximab can induce remission of nephrotic syndrome in the absence of peripheral B-cells. Nephrology (Carlton, Vic.)\| PubMed ID: 26278122	2015
Increased expression of lysosome membrane protein 2 in glomeruli of patients with idiopathic membranous nephropathy. Proteomics\| PubMed ID: 26304790	2015
Hepatocyte Nuclear Factor 1β-Associated Kidney Disease: More than Renal Cysts and Diabetes. Journal of the American Society of Nephrology : JASN\| PubMed ID: 26319241	2016
Differential Expression of Specific Dermatan Sulfate Domains in Renal Pathology. PloS one\| PubMed ID: 26322947	2015
Prevalence of Apparent Therapy-Resistant Hypertension and Its Effect on Outcome in Patients With Chronic Kidney Disease. Hypertension (Dallas, Tex. : 1979)\| PubMed ID: 26351024	2015
Kidney Weight in Living and Postmortal Kidney Donation. Transplantation\| PubMed ID: 26469985	2016
Synthetic ACTH in High Risk Patients with Idiopathic Membranous Nephropathy: A Prospective, Open Label Cohort Study. PloS one\| PubMed ID: 26562836	2015
Acetazolamide Attenuates Lithium-Induced Nephrogenic Diabetes Insipidus. Journal of the American Society of Nephrology : JASN\| PubMed ID: 26574046	2016
Renal Handling of Circulating and Renal-Synthesized Hepcidin and Its Protective Effects against Hemoglobin-Mediated Kidney Injury. Journal of the American Society of Nephrology : JASN\| PubMed ID: 26825531	2016
Thiazide Responsiveness Testing in Patients With Renal Magnesium Wasting and Correlation With Genetic Analysis: A Diagnostic Test Study. American journal of kidney diseases : the official journal of the National Kidney Foundation\| PubMed ID: 26830254	2016
Central arteriovenous anastomosis and hypertension. Lancet (London, England)\| PubMed ID: 26843305	2015
1,25-Vitamin D3 Deficiency Induces Albuminuria. The American journal of pathology\| PubMed ID: 26851346	2016
Quality of chronic kidney disease management in primary care: a retrospective study. Scandinavian journal of primary health care\| PubMed ID: 26853071	2016
Abdominal aortic calcification in patients with CKD. Journal of nephrology\| PubMed ID: 27003153	2017
Should aspirin be used for primary prevention of thrombotic events in patients with membranous nephropathy? Kidney international\| PubMed ID: 27083274	2016
Kidney Dysfunction Increases Mortality and Incident Events after Young Stroke: The FUTURE Study. Cerebrovascular diseases (Basel, Switzerland)\| PubMed ID: 27173119	2016
Pharmacological treatment of primary membranous nephropathy in 2016. Expert review of clinical pharmacology\| PubMed ID: 27535699	2016
Drug therapy management in patients with renal impairment: how to use creatinine-based formulas in clinical practice. European journal of clinical pharmacology\| PubMed ID: 27568310	2016
Minimal change disease and idiopathic FSGS: manifestations of the same disease. Nature reviews. Nephrology\| PubMed ID: 27748392	2016
Hepatic Cyst Infection During Use of the Somatostatin Analog Lanreotide in Autosomal Dominant Polycystic Kidney Disease: An Interim Analysis of the Randomized Open-Label Multicenter DIPAK-1 ... Drug safety\| PubMed ID: 27995519	2017
Lifetime risk of renal replacement therapy in Europe: a population-based study using data from the ERA-EDTA Registry. Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association\| PubMed ID: 28031344	2017
Uremic Solutes in Chronic Kidney Disease and Their Role in Progression. PloS one\| PubMed ID: 28033375	2016
Copeptin, a surrogate marker for arginine vasopressin, is associated with disease severity and progression in IgA nephropathy patients. Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association\| PubMed ID: 28057871	2017
The Clinical Course of Minimal Change Nephrotic Syndrome With Onset in Adulthood or Late Adolescence: A Case Series. American journal of kidney diseases : the official journal of the National Kidney Foundation\| PubMed ID: 28089478	2017
Glomerular disease in 2016: New advances in the treatment of glomerular disease. Nature reviews. Nephrology\| PubMed ID: 28100906	2017
Web-based consultation between general practitioners and nephrologists: a cluster randomized controlled trial. Family practice\| PubMed ID: 28158576	2017
Adherence to chronic kidney disease guidelines in primary care patients is associated with comorbidity. Family practice\| PubMed ID: 28207923	2017
Development and Pretesting of a Questionnaire to Assess Patient Experiences and Satisfaction with Medications (PESaM Questionnaire). The patient\| PubMed ID: 28357591	2017
Cost-effectiveness of eculizumab treatment after kidney transplantation in patients with atypical haemolytic uraemic syndrome. Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association\| PubMed ID: 28391343	2017
Clinical Relevance of Differences in Glomerular Filtration Rate Estimations in Frail Older People by Creatinine- vs. Cystatin C-Based Formulae. Drugs & aging\| PubMed ID: 28405944	2017
Safety of Rituximab Compared with Steroids and Cyclophosphamide for Idiopathic Membranous Nephropathy. Journal of the American Society of Nephrology : JASN\| PubMed ID: 28487395	2017
Urinary Excretion of α-Microglobulin Does Not Predict Graft Loss in Stable Kidney Transplant Recipients. American journal of kidney diseases : the official journal of the National Kidney Foundation\| PubMed ID: 28501240	2017
Lithium-induced NDI: acetazolamide reduces polyuria but does not improve urine concentrating ability. American journal of physiology. Renal physiology\| PubMed ID: 28615247	2017
Use of the Furosemide Fludrocortisone Test to Clinically Assess Distal Tubular Acidification. American journal of kidney diseases : the official journal of the National Kidney Foundation\| PubMed ID: 28634085	2017
Disposition and clinical implications of protein-bound uremic toxins. Clinical science (London, England : 1979)\| PubMed ID: 28667064	2017
A Novel Hypokalemic-Alkalotic Salt-Losing Tubulopathy in Patients with Mutations. Journal of the American Society of Nephrology : JASN\| PubMed ID: 28674042	2017
Living Donor Kidney Transplantation in Atypical Hemolytic Uremic Syndrome: A Case Series. American journal of kidney diseases : the official journal of the National Kidney Foundation\| PubMed ID: 28821363	2017
The Association of Combined Total Kidney and Liver Volume with Pain and Gastrointestinal Symptoms in Patients with Later Stage Autosomal Dominant Polycystic Kidney Disease. American journal of nephrology\| PubMed ID: 28881341	2017
Renal physiology: Prostaglandins in thiazide-induced hyponatraemia: do they hold water? Nature reviews. Nephrology\| PubMed ID: 28944774	2017
Safety and effectiveness of restrictive eculizumab treatment in atypical haemolytic uremic syndrome. Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association\| PubMed ID: 29106598	2018
Reference values of renal tubular function tests are dependent on age and kidney function. Physiological reports\| PubMed ID: 29212860	2017
CD44 is required for the pathogenesis of experimental crescentic glomerulonephritis and collapsing focal segmental glomerulosclerosis. Kidney international\| PubMed ID: 29276101	2018
Interleukin-6 is essential for glomerular immunoglobulin A deposition and the development of renal pathology in Cd37-deficient mice. Kidney international\| PubMed ID: 29551516	2018
Immunological remission in PLA2R-antibody-associated membranous nephropathy: cyclophosphamide versus rituximab. Kidney international\| PubMed ID: 29571438	2018
Effects of sildenafil, metformin, and simvastatin on ADH-independent urine concentration in healthy volunteers. Physiological reports\| PubMed ID: 29611351	2018
General practitioners' perspectives on management of early-stage chronic kidney disease: a focus group study. BMC family practice\| PubMed ID: 29875016	2018
The Calcium-Dependent Protease Calpain-1 Links TRPC6 Activity to Podocyte Injury. Journal of the American Society of Nephrology : JASN\| PubMed ID: 29954830	2018
What Patients with Mild-to-Moderate Kidney Disease Know, Think, and Feel about Their Disease: An In-Depth Interview Study. Journal of the American Board of Family Medicine : JABFM\| PubMed ID: 29986983	2018
Benefit of Eculizumab Compared to Standard of Care Still Unproven in C3 Glomerulopathy. American journal of kidney diseases : the official journal of the National Kidney Foundation\| PubMed ID: 30236630	2018
Nephrotic Syndrome With Mutations in NPHS2: The Role of R229Q and Implications for Genetic Counseling. American journal of kidney diseases : the official journal of the National Kidney Foundation\| PubMed ID: 30241959	2019
The authors reply. Kidney international\| PubMed ID: 30243321	2018
Urine Acidification After Ammonium Chloride. American journal of kidney diseases : the official journal of the National Kidney Foundation\| PubMed ID: 30297083	2018
The Use of N-of-1 Trials to Individualize Treatment in Patients With Renal Magnesium Wasting. American journal of kidney diseases : the official journal of the National Kidney Foundation\| PubMed ID: 30318133	2019
Eculizumab in atypical hemolytic uremic syndrome: strategies toward restrictive use. Pediatric nephrology (Berlin, Germany)\| PubMed ID: 30402748	2019
Is there long-term value of pathology scoring in immunoglobulin A nephropathy? A validation study of the Oxford Classification for IgA Nephropathy (VALIGA) update. Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association\| PubMed ID: 30418652	2020
Effect of Lanreotide on Kidney Function in Patients With Autosomal Dominant Polycystic Kidney Disease: The DIPAK 1 Randomized Clinical Trial. JAMA\| PubMed ID: 30422235	2018
Antibodies Against M-Type Phospholipase Receptor and Prediction of Outcome in Membranous Nephropathy: We are Not There Yet. American journal of nephrology\| PubMed ID: 30472711	2018
Change in albuminuria and subsequent risk of end-stage kidney disease: an individual participant-level consortium meta-analysis of observational studies. The lancet. Diabetes & endocrinology\| PubMed ID: 30635225	2019
Correction to: Eculizumab in atypical hemolytic uremic syndrome: strategies toward restrictive use. Pediatric nephrology (Berlin, Germany)\| PubMed ID: 30645679	2019
Management and treatment of glomerular diseases (part 1): conclusions from a Kidney Disease: Improving Global Outcomes (KDIGO) Controversies Conference. Kidney international\| PubMed ID: 30665568	2019
Pharmacology, Pharmacokinetics and Pharmacodynamics of Eculizumab, and Possibilities for an Individualized Approach to Eculizumab. Clinical pharmacokinetics\| PubMed ID: 30758736	2019
Novel ELISA for thrombospondin type 1 domain-containing 7A autoantibodies in membranous nephropathy. Kidney international\| PubMed ID: 30784662	2019
Placental passage of eculizumab and complement blockade in a newborn. Kidney international\| PubMed ID: 30904074	2019
Lanreotide Reduces Liver Growth In Patients With Autosomal Dominant Polycystic Liver and Kidney Disease. Gastroenterology\| PubMed ID: 31022403	2019
The bias between different albumin assays may affect clinical decision-making. Kidney international\| PubMed ID: 31053386	2019
Predicting kidney failure from longitudinal kidney function trajectory: A comparison of models. PloS one\| PubMed ID: 31071186	2019
The authors reply. Kidney international\| PubMed ID: 31229039	2019
Genetic Identification of Two Novel Loci Associated with Steroid-Sensitive Nephrotic Syndrome. Journal of the American Society of Nephrology : JASN\| PubMed ID: 31263063	2019
Performance of GFR Slope as a Surrogate End Point for Kidney Disease Progression in Clinical Trials: A Statistical Simulation. Journal of the American Society of Nephrology : JASN\| PubMed ID: 31292198	2019
Evaluating Glomerular Filtration Rate Slope as a Surrogate End Point for ESKD in Clinical Trials: An Individual Participant Meta-Analysis of Observational Data. Journal of the American Society of Nephrology : JASN\| PubMed ID: 31292199	2019
Unraveling Hepcidin Plasma Protein Binding: Evidence from Peritoneal Equilibration Testing. Pharmaceuticals (Basel, Switzerland)\| PubMed ID: 31450766	2019
Complement inhibitors are not useful in secondary hemolytic uremic syndromes. Kidney international\| PubMed ID: 31543154	2019
The multifaceted role of iron in renal health and disease. Nature reviews. Nephrology\| PubMed ID: 31554933	2020
The anti-PLA2R antibody in membranous nephropathy: what we know and what remains a decade after its discovery. Kidney international\| PubMed ID: 31611068	2019
Five non-mitochondrial myopathy, encephalopathy, lactic acidosis and stroke-like episodes phenotype adult patients with m.3243A>G mutation after kidney transplantation: follow-up and review ... Clinical kidney journal\| PubMed ID: 31807297	2019
The zinc fingers and homeoboxes 2 protein ZHX2 and its interacting proteins regulate upstream pathways in podocyte diseases. Kidney international\| PubMed ID: 32059999	2020
The complement component C5 is not responsible for the alternative pathway activity in rabbit erythrocyte hemolytic assays during eculizumab treatment. Cellular & molecular immunology\| PubMed ID: 32210393	2020
The genetic architecture of membranous nephropathy and its potential to improve non-invasive diagnosis. Nature communications\| PubMed ID: 32231244	2020
Inhibition of mTOR delayed but could not prevent experimental collapsing focal segmental glomerulosclerosis. Scientific reports\| PubMed ID: 32444668	2020
Treatment-resistant nephrotic syndrome in dense deposit disease: complement-mediated glomerular capillary wall injury? Pediatric nephrology (Berlin, Germany)\| PubMed ID: 32447506	2020
Salt, but not protein intake, is associated with accelerated disease progression in autosomal dominant polycystic kidney disease. Kidney international\| PubMed ID: 32534051	2020
Proteomic Analysis Identifies Distinct Glomerular Extracellular Matrix in Collapsing Focal Segmental Glomerulosclerosis. Journal of the American Society of Nephrology : JASN\| PubMed ID: 32561683	2020
Conversion of Urine Protein-Creatinine Ratio or Urine Dipstick Protein to Urine Albumin-Creatinine Ratio for Use in Chronic Kidney Disease Screening and Prognosis: An Individual Participant-... Annals of internal medicine\| PubMed ID: 32658569	2020
Standardized reporting of monoclonal immunoglobulin-associated renal diseases: recommendations from a Mayo Clinic/Renal Pathology Society Working Group. Kidney international\| PubMed ID: 32709293	2020