Steven E. Guard

Steven E. Guard

Department of Molecular, University of Colorado

Affiliated withUniversity of Colorado

Research Area

Biography

Steven Guard is a Ph.D candidate in the Molecular, Cellular and Developmental Biology Department at the University of Colorado Boulder. He graduated from the University of Cincinnati in 2015 with a bachelor's degree in Chemical Engineering and a bachelor's degree in neurobiology.

His first research experience was in Dr. Nancy Ratner’s lab at Cincinnati Children’s Hospital studying the tumor suppressor gene Merlin. Soon after, he continued his research career as an ASPET SURF fellow in Dr. Zalfa Abdel-Malek’s lab at the University of Cincinnati studying melanoma susceptibility and senescence. As a graduate student in Dr. William Old's lab, he received training in mutliple omics technologies and explored several biological contexts in which they could be applied. Steven spent the beginning of his graduate studies investigating the interaction partners of the CMGC kinase, DYRK1A, and a novel role for this kinase in the regulation of DNA double strand break repair. Recently he has expanded his studies to uncovering novel drug mechanisms by leveraging an unbiased multiomics platform of the proteome, phosphoproteome, transcriptome, metabolome, and thermal proteome profiling.

JoVE Journal Publications

ArticleTotal : 1
Year
Label-Free Immunoprecipitation Mass Spectrometry Workflow for Large-scale Nuclear Interactome Profiling
Publication title

Cited by 9

2019

Other Publications

Article
Year
The nuclear interactome of DYRK1A reveals a functional role in DNA damage repair.

Scientific reports| PubMed ID: 31024071

2019