Christopher C. Ebmeier

Department of Molecular, University of Colorado

Research Area

Biography

Chris Ebmeier received a BS in Biochemistry from the University of Nebraska-Lincoln. He spent several years in the Biotech industry developing manufacturing processes and analytical methods for therapeutic recombinant human hormone peptides. He next pursued graduate work in the lab of Dylan Taatjes at the University of Colorado Boulder receiving a PhD in Biochemistry. His graduate studies involved developing and applying proteomics technologies to investigate the mechanisms of regulated gene expression. Chris is currently working in the lab of William Old in the MCD Biology department at the University of Colorado Boulder, where he advances and promotes proteomics technologies for a wide array of projects.

JoVE Journal Publications

ArticleTotal : 1	Year
Publication title Cited by 9	2019

Other Publications

Article	Year
CDK8 is a positive regulator of transcriptional elongation within the serum response network. Nature structural & molecular biology\| PubMed ID: 20098423	2010
Activator-Mediator binding regulates Mediator-cofactor interactions. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 20534441	2010
Mediator and cohesin connect gene expression and chromatin architecture. Nature\| PubMed ID: 20720539	2010
Molecular architecture of the human Mediator-RNA polymerase II-TFIIF assembly. PLoS biology\| PubMed ID: 21468301	2011
FUS binds the CTD of RNA polymerase II and regulates its phosphorylation at Ser2. Genes & development\| PubMed ID: 23249733	2012
The Mediator complex and transcription regulation. Critical reviews in biochemistry and molecular biology\| PubMed ID: 24088064	2013
TRIM28 regulates RNA polymerase II promoter-proximal pausing and pause release. Nature structural & molecular biology\| PubMed ID: 25173174	2014
Licensing of yeast centrosome duplication requires phosphoregulation of sfi1. PLoS genetics\| PubMed ID: 25340401	2014
Architecture of the Human and Yeast General Transcription and DNA Repair Factor TFIIH. Molecular cell\| PubMed ID: 26340423	2015
Mediator kinase inhibition further activates super-enhancer-associated genes in AML. Nature\| PubMed ID: 26416749	2015
Identification of Mediator Kinase Substrates in Human Cells using Cortistatin A and Quantitative Phosphoproteomics. Cell reports\| PubMed ID: 27050516	2016
A Synonymous Mutation Upstream of the Gene Encoding a Weak-Link Enzyme Causes an Ultrasensitive Response in Growth Rate. Journal of bacteriology\| PubMed ID: 27501982	2016
Human TFIIH Kinase CDK7 Regulates Transcription-Associated Chromatin Modifications. Cell reports\| PubMed ID: 28768201	2017
Specificity of Phosphorylation Responses to Mitogen Activated Protein (MAP) Kinase Pathway Inhibitors in Melanoma Cells. Molecular & cellular proteomics : MCP\| PubMed ID: 29255136	2018
Synonymous mutations make dramatic contributions to fitness when growth is limited by a weak-link enzyme. PLoS genetics\| PubMed ID: 30148850	2018
A Novel Class of ER Membrane Proteins Regulates ER-Associated Endosome Fission. Cell\| PubMed ID: 30220460	2018
The nuclear interactome of DYRK1A reveals a functional role in DNA damage repair. Scientific reports\| PubMed ID: 31024071	2019
Hidden resources in the genome restore PLP synthesis and robust growth after deletion of the essential gene . Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 31712440	2019