visualization-low-level-gamma-radiation-sources-using-low-cost-high

Visualization of Low-Level Gamma Radiation Sources Using a Low-Cost, High-Sensitivity, Omnidirectional Compton Camera

We present experimental protocols for visualizing various low-level gamma radiation sources in the ambient environment. Experiments were conducted by ...

Kitasato University

Kitasato university

This work was aimed at quantification of lactate concentration using proton MR spectroscopy (MRS). We carried out a basic study to clarify the characteristics of signal change and T2 relaxation time of lactate that occur by J coupling in point resolved spectroscopy (PRESS) sequence.

Effect of J coupling and T2 Relaxation in Assessing of Methyl Lactate Signal using PRESS Sequence MR Spectroscopy.

We proposed a new technique for the fast acquisition heavy ion CT (HICT) system based on the measurement of residual range distribution using an intensifying screen and charge coupled device camera. The previously used fast acquisition HICT system had poor electron density resolution. In the new technique, the range shifter thickness is varied over the required dynamic range in the spill of the heavy ion beam at each projection angle and the residual range distribution is determined by a series of acquisition data. We examined the image quality using the contrast noise ratio and the noise power spectrum, and estimated the electron density resolution, using a low-contrast phantom for measurement of electron density resolution. The image quality of the new technique was superior to that of the previous fast acquisition HICT system. Furthermore, the relative electron density resolution was 0.011, which represented an improvement of about 12-fold. Therefore we showed that the new technique was potentially useful in clinical use of HICT, including treatment and quality assurance of heavy ion therapy.

[Study of fast acquisition technique for heavy ion CT system based on the measurement of residual range distribution].

The transportation accuracy of sealed radioisotope sources influences the therapeutic effect of high-dose-rate (HDR) brachytherapy. We have developed a pinhole imaging system for tracking an Ir-192 radiation source during HDR brachytherapy treatment. Our system consists of a dual-pinhole collimator, a scintillator, and a charge-coupled device (CCD) camera. We acquired stereo-shifted images to infer the source position in three dimensions using a dual pinhole collimator with 1.0 mm diameter pinholes. The CCD camera captured consecutive images of scintillation light that corresponds to the source positions every 2 s. The system automatically tracks scintillation light points using template-matching technique and measured the source positions therefrom. By integrating a series of CCD images, we could infer the source dwell time from the pixel values in the integrated image. We investigated the tracking accuracy of our system in monitoring simulated brachytherapy as it would be performed for cervical cancer by using water as a stand-in for human tissue. Ir-192 pellet was moved through a water tank using tandem and ovoid applicators. The CCD camera captured clear images of the scintillation light produced by the underwater Ir-192 source in conditions equivalent to common clinical situations. The differences between the measured and the reference 3D source positions and dwell times were 1.5  ±  0.7 mm and 0.8  ±  0.4 s, respectively. This system has the potential to track in vivo Ir-192 source in real time and may prove a useful tool for quality assurance during HDR brachytherapy treatments in clinical settings.

Article	Year
Effect of J coupling and T2 Relaxation in Assessing of Methyl Lactate Signal using PRESS Sequence MR Spectroscopy. Igaku butsuri : Nihon Igaku Butsuri Gakkai kikanshi = Japanese journal of medical physics : an official journal of Japan Society of Medical Physics\| PubMed ID: 16135894	2005
[Study of fast acquisition technique for heavy ion CT system based on the measurement of residual range distribution]. Igaku butsuri : Nihon Igaku Butsuri Gakkai kikanshi = Japanese journal of medical physics : an official journal of Japan Society of Medical Physics\| PubMed ID: 24592673	2012
Automated source tracking with a pinhole imaging system during high-dose-rate brachytherapy treatment. Physics in medicine and biology\| PubMed ID: 29923497	2018

Hiroshi Muraishi

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