Ken Mackie

Department of Psychological and Brain Sciences, Indiana University

Research Area

Biography

Ken Mackie has not added Biography.
If you are Ken Mackie and would like to personalize this page please email our Author Liaison for assistance.

JoVE Journal Publications

ArticleTotal : 1	Year
Publication title Cited by 20	2020

Other Publications

Article	Year
Identification of the sites of 2-arachidonoylglycerol synthesis and action imply retrograde endocannabinoid signaling at both GABAergic and glutamatergic synapses in the ventral tegmental ar... Neuropharmacology\| PubMed ID: 17655884	2008
CB2-receptor stimulation attenuates TNF-alpha-induced human endothelial cell activation, transendothelial migration of monocytes, and monocyte-endothelial adhesion. American journal of physiology. Heart and circulatory physiology\| PubMed ID: 17660390	2007
From active ingredients to the discovery of the targets: the cannabinoid receptors. Chemistry & biodiversity\| PubMed ID: 17712815	2007
Understanding cannabinoid psychoactivity with mouse genetic models. PLoS biology\| PubMed ID: 17927451	2007
Enzymatic machinery for endocannabinoid biosynthesis associated with calcium stores in glutamatergic axon terminals. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 18234884	2008
Regulation of CB1 cannabinoid receptor internalization by a promiscuous phosphorylation-dependent mechanism. Journal of neurochemistry\| PubMed ID: 18331587	2008
Signaling via CNS cannabinoid receptors. Molecular and cellular endocrinology\| PubMed ID: 18336996	2008
Cannabinoid receptors: where they are and what they do. Journal of neuroendocrinology\| PubMed ID: 18426493	2008
Cannabinoid CB2 receptors in the enteric nervous system modulate gastrointestinal contractility in lipopolysaccharide-treated rats. American journal of physiology. Gastrointestinal and liver physiology\| PubMed ID: 18483180	2008
Endocannabinoid signaling controls pyramidal cell specification and long-range axon patterning. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 18562289	2008
Wiring and firing neuronal networks: endocannabinoids take center stage. Current opinion in neurobiology\| PubMed ID: 18801434	2008
Building a new conceptual framework for receptor heteromers. Nature chemical biology\| PubMed ID: 19219011	2009
Molecular architecture of endocannabinoid signaling at nociceptive synapses mediating analgesia. The European journal of neuroscience\| PubMed ID: 19453631	2009
Cannabinoid CB1 receptor-dependent long-term depression in autaptic excitatory neurons. Journal of neurophysiology\| PubMed ID: 19494194	2009
Cannabinoid signaling in inhibitory autaptic hippocampal neurons. Neuroscience\| PubMed ID: 19501632	2009
Repeated homotypic stress elevates 2-arachidonoylglycerol levels and enhances short-term endocannabinoid signaling at inhibitory synapses in basolateral amygdala. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology\| PubMed ID: 19675536	2009
Get stoned in GABAergic synapses. Nature neuroscience\| PubMed ID: 19710646	2009
Monoacylglycerol lipase limits the duration of endocannabinoid-mediated depolarization-induced suppression of excitation in autaptic hippocampal neurons. Molecular pharmacology\| PubMed ID: 19767452	2009
The putative cannabinoid receptor GPR55 affects osteoclast function in vitro and bone mass in vivo. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 19805329	2009
Characterization of cannabinoid-1 receptors in the locus coeruleus: relationship with mu-opioid receptors. Brain research\| PubMed ID: 19931229	2010
Regulation of MAP kinase-directed mitogenic and protein kinase B-mediated signaling by cannabinoid receptor type 1 in skeletal muscle cells. Diabetes\| PubMed ID: 19933999	2010
CB1 cannabinoid receptors promote oxidative stress and cell death in murine models of doxorubicin-induced cardiomyopathy and in human cardiomyocytes. Cardiovascular research\| PubMed ID: 19942623	2010
Loss of cannabinoid CB1 receptor expression in the 6-hydroxydopamine-induced nigrostriatal terminal lesion model of Parkinson's disease in the rat. Brain research bulletin\| PubMed ID: 20097273	2010
JWH018, a common constituent of 'Spice' herbal blends, is a potent and efficacious cannabinoid CB receptor agonist. British journal of pharmacology\| PubMed ID: 20100276	2010
Differential effects of CB(1) neutral antagonists and inverse agonists on gastrointestinal motility in mice. Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society\| PubMed ID: 20180825	2010
Transcriptional regulation of cannabinoid receptor-1 expression in the liver by retinoic acid acting via retinoic acid receptor-gamma. The Journal of biological chemistry\| PubMed ID: 20410309	2010
Alterations in the hippocampal endocannabinoid system in diet-induced obese mice. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 20445053	2010
CB2: a cannabinoid receptor with an identity crisis. British journal of pharmacology\| PubMed ID: 20590558	2010
Dynamic changes of CB1-receptor expression in hippocampi of epileptic mice and humans. Epilepsia\| PubMed ID: 20618415	2010
Architecture of cannabinoid signaling in mouse retina. The Journal of comparative neurology\| PubMed ID: 20653038	2010
The serine hydrolase ABHD6 controls the accumulation and efficacy of 2-AG at cannabinoid receptors. Nature neuroscience\| PubMed ID: 20657592	2010
Endocannabinoid involvement in endometriosis. Pain\| PubMed ID: 20833475	2010
Laserspray ionization, a new method for protein analysis directly from tissue at atmospheric pressure with ultrahigh mass resolution and electron transfer dissociation. Molecular & cellular proteomics : MCP\| PubMed ID: 20855542	2011
Differential subcellular recruitment of monoacylglycerol lipase generates spatial specificity of 2-arachidonoyl glycerol signaling during axonal pathfinding. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 20962221	2010
WNT signaling in activated microglia is proinflammatory. Glia\| PubMed ID: 20967887	2011
Requirement of cannabinoid CB(1) receptors in cortical pyramidal neurons for appropriate development of corticothalamic and thalamocortical projections. The European journal of neuroscience\| PubMed ID: 21050275	2010
Presynaptic CB1 receptors regulate synaptic plasticity at cerebellar parallel fiber synapses. Journal of neurophysiology\| PubMed ID: 21084685	2011
Expression of G protein-coupled receptors and related proteins in HEK293, AtT20, BV2, and N18 cell lines as revealed by microarray analysis. BMC genomics\| PubMed ID: 21214938	2011
CP47,497-C8 and JWH073, commonly found in 'Spice' herbal blends, are potent and efficacious CB(1) cannabinoid receptor agonists. European journal of pharmacology\| PubMed ID: 21333643	2011
Imaging mass spectrometry in transmission geometry. Rapid communications in mass spectrometry : RCM\| PubMed ID: 21337644	2011
Molecular reorganization of endocannabinoid signalling in Alzheimer's disease. Brain : a journal of neurology\| PubMed ID: 21459826	2011
Δ9-Tetrahydrocannabinol (Δ9-THC) attenuates mouse sperm motility and male fecundity. British journal of pharmacology\| PubMed ID: 21615727	2012
The atypical cannabinoid O-1602 protects against experimental colitis and inhibits neutrophil recruitment. Inflammatory bowel diseases\| PubMed ID: 21744421	2011
Molecular model of cannabis sensitivity in developing neuronal circuits. Trends in pharmacological sciences\| PubMed ID: 21757242	2011
Recruitment of prefrontal cortical endocannabinoid signaling by glucocorticoids contributes to termination of the stress response. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 21775596	2011
Activation of orexin 1 receptors in the periaqueductal gray of male rats leads to antinociception via retrograde endocannabinoid (2-arachidonoylglycerol)-induced disinhibition. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 21994376	2011
The CB1 cannabinoid receptor C-terminus regulates receptor desensitization in autaptic hippocampal neurones. British journal of pharmacology\| PubMed ID: 22014214	2012
Differential signalling in human cannabinoid CB1 receptors and their splice variants in autaptic hippocampal neurones. British journal of pharmacology\| PubMed ID: 22014238	2012
Functional selectivity in CB(2) cannabinoid receptor signaling and regulation: implications for the therapeutic potential of CB(2) ligands. Molecular pharmacology\| PubMed ID: 22064678	2012
Quinpirole elicits differential in vivo changes in the pre- and postsynaptic distributions of dopamine D₂ receptors in mouse striatum: relation to cannabinoid-1 (CB₁) receptor targeting. Psychopharmacology\| PubMed ID: 22160162	2012
CB₂: therapeutic target-in-waiting. Progress in neuro-psychopharmacology & biological psychiatry\| PubMed ID: 22197668	2012
Plasticity of mouse enteric synapses mediated through endocannabinoid and purinergic signaling. Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society\| PubMed ID: 22235973	2012
Cannabinoid 1 receptor promotes cardiac dysfunction, oxidative stress, inflammation, and fibrosis in diabetic cardiomyopathy. Diabetes\| PubMed ID: 22315315	2012
Differential distribution of diacylglycerol lipase-alpha and N-acylphosphatidylethanolamine-specific phospholipase d immunoreactivity in the superficial spinal dorsal horn of rats. Glia\| PubMed ID: 22573306	2012
CB₂ cannabinoid receptors inhibit synaptic transmission when expressed in cultured autaptic neurons. Neuropharmacology\| PubMed ID: 22579668	2012
A Primary Cortical Input to Hippocampus Expresses a Pathway-Specific and Endocannabinoid-Dependent Form of Long-Term Potentiation. eNeuro\| PubMed ID: 27517090	2016
Presynaptic CB(1) cannabinoid receptors control frontocortical serotonin and glutamate release--species differences. Neurochemistry international\| PubMed ID: 22609378	2012
Characterisation of cannabinoid 1 receptor expression in the perikarya, and peripheral and spinal processes of primary sensory neurons. Brain structure & function\| PubMed ID: 22618437	2013
Activation of type 5 metabotropic glutamate receptors and diacylglycerol lipase-α initiates 2-arachidonoylglycerol formation and endocannabinoid-mediated analgesia. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 22787031	2012
Cannabinoid-1 receptors in the mouse ventral pallidum are targeted to axonal profiles expressing functionally opposed opioid peptides and contacting N-acylphosphatidylethanolamine-hydrolyzin... Neuroscience\| PubMed ID: 22863674	2012
Laserspray ionization imaging of multiply charged ions using a commercial vacuum MALDI ion source. Analytical chemistry\| PubMed ID: 23009673	2012
Uncoupling of the endocannabinoid signalling complex in a mouse model of fragile X syndrome. Nature communications\| PubMed ID: 23011134	2012
Brain CB₁ receptor expression following lipopolysaccharide-induced inflammation. Neuroscience\| PubMed ID: 23041513	2012
Endocannabinoid-mediated long-term depression of afferent excitatory synapses in hippocampal pyramidal cells and GABAergic interneurons. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 23055515	2012
Downregulation of cannabinoid receptor 1 from neuropeptide Y interneurons in the basal ganglia of patients with Huntington's disease and mouse models. The European journal of neuroscience\| PubMed ID: 23167744	2013
CaMKII regulates diacylglycerol lipase-α and striatal endocannabinoid signaling. Nature neuroscience\| PubMed ID: 23502535	2013
Cannabinoid receptors are widely expressed in goldfish: molecular cloning of a CB2-like receptor and evaluation of CB1 and CB2 mRNA expression profiles in different organs. Fish physiology and biochemistry\| PubMed ID: 23504102	2013
GPR55, a G-protein coupled receptor for lysophosphatidylinositol, plays a role in motor coordination. PloS one\| PubMed ID: 23565223	2013
Fmr1 deletion enhances and ultimately desensitizes CB(1) signaling in autaptic hippocampal neurons. Neurobiology of disease\| PubMed ID: 23578490	2013
A role for O-1602 and G protein-coupled receptor GPR55 in the control of colonic motility in mice. Neuropharmacology\| PubMed ID: 23603203	2013
Diacylglycerol lipaseα (DAGLα) and DAGLβ cooperatively regulate the production of 2-arachidonoyl glycerol in autaptic hippocampal neurons. Molecular pharmacology\| PubMed ID: 23748223	2013
Two novel mutations in ABHD12: expansion of the mutation spectrum in PHARC and assessment of their functional effects. Human mutation\| PubMed ID: 24027063	2013
CB1 cannabinoid receptors couple to focal adhesion kinase to control insulin release. The Journal of biological chemistry\| PubMed ID: 24089517	2013
Mastering tricyclic ring systems for desirable functional cannabinoid activity. European journal of medicinal chemistry\| PubMed ID: 24125850	2013
Impaired fear memory specificity associated with deficient endocannabinoid-dependent long-term plasticity. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology\| PubMed ID: 24457285	2014
Gβ₂ mimics activation kinetic slowing of CaV2.2 channels by noradrenaline in rat sympathetic neurons. Biochemical and biophysical research communications\| PubMed ID: 24513289	2014
The mismatch negativity: a translational probe of auditory processing in cannabis users. Biological psychiatry\| PubMed ID: 24560430	2014
Multiple mechanistically distinct modes of endocannabinoid mobilization at central amygdala glutamatergic synapses. Neuron\| PubMed ID: 24607231	2014
Mutation of putative GRK phosphorylation sites in the cannabinoid receptor 1 (CB1R) confers resistance to cannabinoid tolerance and hypersensitivity to cannabinoids in mice. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 24719095	2014
Chronic cannabinoid receptor 2 activation reverses paclitaxel neuropathy without tolerance or cannabinoid receptor 1-dependent withdrawal. Biological psychiatry\| PubMed ID: 24853387	2015
Transmission geometry laserspray ionization vacuum using an atmospheric pressure inlet. Analytical chemistry\| PubMed ID: 24896880	2014
Ligand-specific endocytic dwell times control functional selectivity of the cannabinoid receptor 1. Nature communications\| PubMed ID: 25081814	2014
CB2 Cannabinoid receptors as a therapeutic target-what does the future hold? Molecular pharmacology\| PubMed ID: 25106425	2014
Programming of neural cells by (endo)cannabinoids: from physiological rules to emerging therapies. Nature reviews. Neuroscience\| PubMed ID: 25409697	2014
Cannabinoid receptor 1 promotes hepatocellular carcinoma initiation and progression through multiple mechanisms. Hepatology (Baltimore, Md.)\| PubMed ID: 25580584	2015
Cannabinoid receptor-interacting protein 1a modulates CB1 receptor signaling and regulation. Molecular pharmacology\| PubMed ID: 25657338	2015
CB1 Knockout Mice Unveil Sustained CB2-Mediated Antiallodynic Effects of the Mixed CB1/CB2 Agonist CP55,940 in a Mouse Model of Paclitaxel-Induced Neuropathic Pain. Molecular pharmacology\| PubMed ID: 25904556	2015
Molecular-interaction and signaling profiles of AM3677, a novel covalent agonist selective for the cannabinoid 1 receptor. ACS chemical neuroscience\| PubMed ID: 25978068	2015
An animal model of female adolescent cannabinoid exposure elicits a long-lasting deficit in presynaptic long-term plasticity. Neuropharmacology\| PubMed ID: 25979486	2015
Cannabinoid-induced chemotaxis in bovine corneal epithelial cells. Investigative ophthalmology & visual science\| PubMed ID: 26024113	2015
Tolerance to the antinociceptive effects of chronic morphine requires c-Jun N-terminal kinase. Molecular pain\| PubMed ID: 26065412	2015
Adolescent cannabis exposure interacts with mutant DISC1 to produce impaired adult emotional memory. Neurobiology of disease\| PubMed ID: 26093170	2015
Ultrastructural evidence for synaptic contacts between cortical noradrenergic afferents and endocannabinoid-synthesizing post-synaptic neurons. Neuroscience\| PubMed ID: 26162236	2015
Aiming for allosterism: Evaluation of allosteric modulators of CB1 in a neuronal model. Pharmacological research\| PubMed ID: 26211948	2015
Drug detection and quantification directly from tissue using novel ionization methods for mass spectrometry. European journal of mass spectrometry (Chichester, England)\| PubMed ID: 26307700	2015
Distribution of the Endocannabinoid System in the Central Nervous System. Handbook of experimental pharmacology\| PubMed ID: 26408158	2015
An Introduction to the Endogenous Cannabinoid System. Biological psychiatry\| PubMed ID: 26698193	2016
Role of GPR55 during Axon Growth and Target Innervation. eNeuro\| PubMed ID: 26730399	2015
Stress induces analgesia via orexin 1 receptor-initiated endocannabinoid/CB1 signaling in the mouse periaqueductal gray. Neuropharmacology\| PubMed ID: 26907809	2016
Matrix-Assisted Ionization on a Portable Mass Spectrometer: Analysis Directly from Biological and Synthetic Materials. Analytical chemistry\| PubMed ID: 26938428	2016
Lipidomics profile of a NAPE-PLD KO mouse provides evidence of a broader role of this enzyme in lipid metabolism in the brain. Biochimica et biophysica acta\| PubMed ID: 26956082	2016
Cannabinoids Occlude the HIV-1 Tat-Induced Decrease in GABAergic Neurotransmission in Prefrontal Cortex Slices. Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology\| PubMed ID: 26993829	2016
Mechanisms of Biased β-Arrestin-Mediated Signaling Downstream from the Cannabinoid 1 Receptor. Molecular pharmacology\| PubMed ID: 27009233	2016
A broad-based study on hyphenating new ionization technologies with MS/MS for PTMs and tissue characterization. Proteomics\| PubMed ID: 27093917	2016
Broad impact of deleting endogenous cannabinoid hydrolyzing enzymes and the CB1 cannabinoid receptor on the endogenous cannabinoid-related lipidome in eight regions of the mouse brain. Pharmacological research\| PubMed ID: 27109320	2016
Where's my entourage? The curious case of 2-oleoylglycerol, 2-linolenoylglycerol, and 2-palmitoylglycerol. Pharmacological research\| PubMed ID: 27117667	2016
A pro-nociceptive phenotype unmasked in mice lacking fatty-acid amide hydrolase. Molecular pain\| PubMed ID: 27178246	2016
Functional Selectivity of CB2 Cannabinoid Receptor Ligands at a Canonical and Noncanonical Pathway. The Journal of pharmacology and experimental therapeutics\| PubMed ID: 27194477	2016
Hierarchical glucocorticoid-endocannabinoid interplay regulates the activation of the nucleus accumbens by insulin. Brain research bulletin\| PubMed ID: 27208730	2016
Western Blotting of the Endocannabinoid System. Methods in molecular biology (Clifton, N.J.)\| PubMed ID: 27245910	2016
Quantitation of Plasma Membrane (G Protein-Coupled) Receptor Trafficking in Cultured Cells. Methods in molecular biology (Clifton, N.J.)\| PubMed ID: 27245911	2016
Orexins contribute to restraint stress-induced cocaine relapse by endocannabinoid-mediated disinhibition of dopaminergic neurons. Nature communications\| PubMed ID: 27448020	2016
Mice Expressing a "Hyper-Sensitive" Form of the Cannabinoid Receptor 1 (CB1) Are Neither Obese Nor Diabetic. PloS one\| PubMed ID: 27501235	2016
Spatial Distribution of the Cannabinoid Type 1 and Capsaicin Receptors May Contribute to the Complexity of Their Crosstalk. Scientific reports\| PubMed ID: 27653550	2016
Novel indole-based compounds that differentiate alkylindole-sensitive receptors from cannabinoid receptors and microtubules: Characterization of their activity on glioma cell migration. Pharmacological research\| PubMed ID: 27832960	2017
Two Janus Cannabinoids That Are Both CB2 Agonists and CB1 Antagonists. The Journal of pharmacology and experimental therapeutics\| PubMed ID: 27927913	2017
Inflammation of peripheral tissues and injury to peripheral nerves induce differing effects in the expression of the calcium-sensitive N-arachydonoylethanolamine-synthesizing enzyme and rela... The Journal of comparative neurology\| PubMed ID: 27997038	2017
Endocannabinoid signalling modulates susceptibility to traumatic stress exposure. Nature communications\| PubMed ID: 28348378	2017
Cannabinoid CB1 receptor overactivity contributes to the pathogenesis of idiopathic pulmonary fibrosis. JCI insight\| PubMed ID: 28422760	2017
Mice expressing a "hyper-sensitive" form of the CB1 cannabinoid receptor (CB1) show modestly enhanced alcohol preference and consumption. PloS one\| PubMed ID: 28426670	2017
Inflammatory and Neuropathic Nociception is Preserved in GPR55 Knockout Mice. Scientific reports\| PubMed ID: 28428628	2017
Endocannabinoid signaling in hypothalamic circuits regulates arousal from general anesthesia in mice. The Journal of clinical investigation\| PubMed ID: 28463228	2017
Modulation of CB1 cannabinoid receptor by allosteric ligands: Pharmacology and therapeutic opportunities. Neuropharmacology\| PubMed ID: 28527758	2017
Cannabinoid CB Agonist GW405833 Suppresses Inflammatory and Neuropathic Pain through a CB Mechanism that is Independent of CB Receptors in Mice. The Journal of pharmacology and experimental therapeutics\| PubMed ID: 28592614	2017
A GPR119 Signaling System in the Murine Eye Regulates Intraocular Pressure in a Sex-Dependent Manner. Investigative ophthalmology & visual science\| PubMed ID: 28593245	2017
Discovery and characterization of two novel CB1 receptor splice variants with modified N-termini in mouse. Journal of neurochemistry\| PubMed ID: 28608535	2017
Positive Allosteric Modulation of Cannabinoid Receptor Type 1 Suppresses Pathological Pain Without Producing Tolerance or Dependence. Biological psychiatry\| PubMed ID: 28823711	2018
Chronic Adolescent Δ-Tetrahydrocannabinol Treatment of Male Mice Leads to Long-Term Cognitive and Behavioral Dysfunction, Which Are Prevented by Concurrent Cannabidiol Treatment. Cannabis and cannabinoid research\| PubMed ID: 29098186	2017
Cannabinoid-1 receptor deletion in podocytes mitigates both glomerular and tubular dysfunction in a mouse model of diabetic nephropathy. Diabetes, obesity & metabolism\| PubMed ID: 29106063	2018
Enantiomer-specific positive allosteric modulation of CB signaling in autaptic hippocampal neurons. Pharmacological research\| PubMed ID: 29158048	2018
Synthesis of Photoswitchable Δ-Tetrahydrocannabinol Derivatives Enables Optical Control of Cannabinoid Receptor 1 Signaling. Journal of the American Chemical Society\| PubMed ID: 29161035	2017
Slowly Signaling G Protein-Biased CB Cannabinoid Receptor Agonist LY2828360 Suppresses Neuropathic Pain with Sustained Efficacy and Attenuates Morphine Tolerance and Dependence. Molecular pharmacology\| PubMed ID: 29192123	2018
Endocannabinoid-Specific Impairment in Synaptic Plasticity in Striatum of Huntington's Disease Mouse Model. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 29192125	2018
GPR55 regulates intraepithelial lymphocyte migration dynamics and susceptibility to intestinal damage. Science immunology\| PubMed ID: 29222090	2017
Δ-Tetrahydrocannabinol changes the brain lipidome and transcriptome differentially in the adolescent and the adult. Biochimica et biophysica acta. Molecular and cell biology of lipids\| PubMed ID: 29408467	2018
Role of Striatal Direct Pathway 2-Arachidonoylglycerol Signaling in Sociability and Repetitive Behavior. Biological psychiatry\| PubMed ID: 29458998	2018
Short-Term Genetic Selection for Adolescent Locomotor Sensitivity to Delta9-Tetrahydrocannabinol (THC). Behavior genetics\| PubMed ID: 29550900	2018
Cannabidiol Inhibits Endocannabinoid Signaling in Autaptic Hippocampal Neurons. Molecular pharmacology\| PubMed ID: 29669714	2018
Controlled-Deactivation CB1 Receptor Ligands as a Novel Strategy to Lower Intraocular Pressure. Pharmaceuticals (Basel, Switzerland)\| PubMed ID: 29786643	2018
Analysis of Endocannabinoid System in Rat Testis During the First Spermatogenetic Wave. Frontiers in endocrinology\| PubMed ID: 29896156	2018
Synthetic peripherally-restricted cannabinoid suppresses chemotherapy-induced peripheral neuropathy pain symptoms by CB1 receptor activation. Neuropharmacology\| PubMed ID: 29981335	2018
Neuroprotective effects of fatty acid amide hydrolase catabolic enzyme inhibition in a HIV-1 Tat model of neuroAIDS. Neuropharmacology\| PubMed ID: 30114402	2018
( R)- N-(1-Methyl-2-hydroxyethyl)-13-( S)-methyl-arachidonamide (AMG315): A Novel Chiral Potent Endocannabinoid Ligand with Stability to Metabolizing Enzymes. Journal of medicinal chemistry\| PubMed ID: 30196704	2018
Sex-dependent effects of in utero cannabinoid exposure on cortical function. eLife\| PubMed ID: 30201092	2018
Median nerve stimulation induces analgesia via orexin-initiated endocannabinoid disinhibition in the periaqueductal gray. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 30348772	2018
Cannabinoid CB2 Agonist AM1710 Differentially Suppresses Distinct Pathological Pain States and Attenuates Morphine Tolerance and Withdrawal. Molecular pharmacology\| PubMed ID: 30504240	2019
Cannabidiol's Upregulation of -acyl Ethanolamines in the Central Nervous System Requires -acyl Phosphatidyl Ethanolamine-Specific Phospholipase D. Cannabis and cannabinoid research\| PubMed ID: 30515459	2018
Broad and Region-Specific Impacts of the Synthetic Cannabinoid CP 55,940 in Adolescent and Adult Female Mouse Brains. Frontiers in molecular neuroscience\| PubMed ID: 30542263	2018
GPR55 controls functional differentiation of self-renewing epithelial progenitors for salivation. JCI insight\| PubMed ID: 30830860	2019
Protective Effect of N-Arachidonoyl Glycine-GPR18 Signaling after Excitotoxical Lesion in Murine Organotypic Hippocampal Slice Cultures. International journal of molecular sciences\| PubMed ID: 30871175	2019
Evidence for a GPR18 Role in Chemotaxis, Proliferation, and the Course of Wound Closure in the Cornea. Cornea\| PubMed ID: 30969262	2019
Ultrastructural localization of cannabinoid CB1 and mGluR5 receptors in the prefrontal cortex and amygdala. The Journal of comparative neurology\| PubMed ID: 31008528	2019
Self-administration of edible Δ-tetrahydrocannabinol and associated behavioral effects in mice. Drug and alcohol dependence\| PubMed ID: 31029878	2019
Elevated Levels of Arachidonic Acid-Derived Lipids Including Prostaglandins and Endocannabinoids Are Present Throughout ABHD12 Knockout Brains: Novel Insights Into the Neurodegenerative Phen... Frontiers in molecular neuroscience\| PubMed ID: 31213981	2019
Cannabinoid receptor-mediated modulation of inhibitory inputs to mitral cells in the main olfactory bulb. Journal of neurophysiology\| PubMed ID: 31215302	2019
Chronic adolescent exposure to ∆9-tetrahydrocannabinol decreases NMDA current and extrasynaptic plasmalemmal density of NMDA GluN1 subunits in the prelimbic cortex of adult male mice. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology\| PubMed ID: 31323660	2020
Inhibitory Control Deficits Associated with Upregulation of CBR in the HIV-1 Tat Transgenic Mouse Model of Hand. Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology\| PubMed ID: 31372820	2019
Cannabinoid Exposure via Lactation in Rats Disrupts Perinatal Programming of the Gamma-Aminobutyric Acid Trajectory and Select Early-Life Behaviors. Biological psychiatry\| PubMed ID: 31653479	2020
Life-long epigenetic programming of cortical architecture by maternal 'Western' diet during pregnancy. Molecular psychiatry\| PubMed ID: 31735910	2020
Application of Fluorine- and Nitrogen-Walk Approaches: Defining the Structural and Functional Diversity of 2-Phenylindole Class of Cannabinoid 1 Receptor Positive Allosteric Modulators. Journal of medicinal chemistry\| PubMed ID: 31756109	2020
c-Jun N terminal kinase signaling pathways mediate cannabinoid tolerance in an agonist-specific manner. Neuropharmacology\| PubMed ID: 31758947	2020
Interference with the Cannabinoid Receptor CB1R Results in Miswiring of GnRH3 and AgRP1 Axons in Zebrafish Embryos. International journal of molecular sciences\| PubMed ID: 31881740	2019
Endocannabinoid Signaling Collapse Mediates Stress-Induced Amygdalo-Cortical Strengthening. Neuron\| PubMed ID: 31948734	2020
One-Stop Microfluidic Assembly of Human Brain Organoids To Model Prenatal Cannabis Exposure. Analytical chemistry\| PubMed ID: 32070103	2020
Endocannabinoid genetic variation enhances vulnerability to THC reward in adolescent female mice. Science advances\| PubMed ID: 32095523	2020
A Glial-Neuronal Circuit in the Median Eminence Regulates Thyrotropin-Releasing Hormone-Release via the Endocannabinoid System. iScience\| PubMed ID: 32143135	2020
Components of Endocannabinoid Signaling System are Expressed in the Perinatal Mouse Cerebellum and Required for its Normal Development. eNeuro\| PubMed ID: 32179579	2020