international-expert-consensus-recommendations-for-neonatal

International Expert Consensus and Recommendations for Neonatal Pneumothorax Ultrasound Diagnosis and Ultrasound-guided Thoracentesis Procedure

Pneumothorax (PTX) represents accumulation of the air in the pleural space. A large or tension pneumothorax can collapse the lung and cause hemodynamic ...

Puerta del Mar University Hospital

Preterm small-for-gestational-age (SGA) infants are at risk for a high mortality rate and impaired cognitive development. Only a few studies have focused on amplitude-integrated EEG (aEEG) in preterm SGA infants. They have been shown to have a slower rate of brain maturation, but these findings have not consistently been related to neurodevelopmental outcomes. The aim of our study was to evaluate early aEEG monitoring in SGA compared with adequate-for-gestational-age preterms.

Amplitude-Integrated EEG and Brain Sparing in Preterm Small-for-Gestational-Age Infants.

We describe our experience with helmet-delivered continuous positive airway pressure in five preterm newborns. We analyzed oxygen requirement, arterial oxygen saturation, respiratory rate, medium arterial pressure, heart rate, apneic spells and patient's comfort. The patients' vital signs or pain scale were not different before and after treatment.

Feasibility of Helmet-delivered Continous Positive Airway Pressure in Very Low Birthweight Infants.

Our objective was to determine if broad spectrum antibiotics (BSA) are associated with multi-resistant bacterial (MRB) infections in neonatal patients. We conducted a case-control study with two groups of patients: those with and without a MRB infection. We included 43 cases and 43 controls. MRB strains were: 21 S. maltophila (49%), 11 ESBL-producing Enterobacteriae (25%), 8 P. aeruginosa (19%) and 3 MRSA (7%). Odds ratio (OR) for MRB after seven days of carbapenems was 4.25 (95% confidence interval (CI) 1.4-17.4) and OR for MRB after seven days of third generation cephalosporin was 8 (95% CI 1.1-34.9). BSA longer than seven days, increases MRB infections 22.5 times in patients with bronchopulmonary dysplasia (BPD). Our data show a clear association between the use of BSA and the development of MRB infections, especially in BPD. Although we cannot state this is a causal relationship, we can recommend avoiding prolonged treatment with these antibiotics in preterm babies at risk of BPD.

Article	Year
Amplitude-Integrated EEG and Brain Sparing in Preterm Small-for-Gestational-Age Infants. Journal of clinical neurophysiology : official publication of the American Electroencephalographic Society\| PubMed ID: 28873072	2017
Feasibility of Helmet-delivered Continous Positive Airway Pressure in Very Low Birthweight Infants. Indian pediatrics\| PubMed ID: 29503275	2018
Broad spectrum antibiotics in newborns increase multi-drug resistant infections. Journal of chemotherapy (Florence, Italy)\| PubMed ID: 30676292	2019

Almudena Alonso-Ojembarrena

Biography

JoVE Journal Publications

Other Publications