Torben Heick Jensen

Department of Molecular Biology and Genetics, Aarhus University

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title Cited by 10	2020

Other Publications

Article	Year
Interactions between mRNA export commitment, 3'-end quality control, and nuclear degradation. Molecular and cellular biology\| PubMed ID: 12417728	2002
Early formation of mRNP: license for export or quality control? Molecular cell\| PubMed ID: 12769839	2003
Localization of nuclear retained mRNAs in Saccharomyces cerevisiae. RNA (New York, N.Y.)\| PubMed ID: 12923254	2003
Modulation of transcription affects mRNP quality. Molecular cell\| PubMed ID: 15494310	2004
Dramatically improved RNA in situ hybridization signals using LNA-modified probes. RNA (New York, N.Y.)\| PubMed ID: 16177135	2005
The role of the Brr5/Ysh1 C-terminal domain and its homolog Syc1 in mRNA 3'-end processing in Saccharomyces cerevisiae. RNA (New York, N.Y.)\| PubMed ID: 16431986	2006
A novel plasmid-based microarray screen identifies suppressors of rrp6Delta in Saccharomyces cerevisiae. Molecular and cellular biology\| PubMed ID: 17101774	2007
Dissecting mechanisms of nuclear mRNA surveillance in THO/sub2 complex mutants. The EMBO journal\| PubMed ID: 17410208	2007
Nuclear mRNA surveillance in THO/sub2 mutants is triggered by inefficient polyadenylation. Molecular cell\| PubMed ID: 18614048	2008
The T body, a new cytoplasmic RNA granule in Saccharomyces cerevisiae. Molecular and cellular biology\| PubMed ID: 18678648	2008
Exonucleolysis is required for nuclear mRNA quality control in yeast THO mutants. RNA (New York, N.Y.)\| PubMed ID: 18824516	2008
RNA exosome depletion reveals transcription upstream of active human promoters. Science (New York, N.Y.)\| PubMed ID: 19056938	2008
Assembly of export-competent mRNP: it's all about being connected. Molecular cell\| PubMed ID: 19187754	2009
Assembly of an export-competent mRNP is needed for efficient release of the 3'-end processing complex after polyadenylation. Molecular and cellular biology\| PubMed ID: 19635808	2009
The yeast 5'-3' exonuclease Rat1p functions during transcription elongation by RNA polymerase II. Molecular cell\| PubMed ID: 20188675	2010
The human core exosome interacts with differentially localized processive RNases: hDIS3 and hDIS3L. The EMBO journal\| PubMed ID: 20531386	2010
Crosstalk between mRNA 3' end processing and transcription initiation. Molecular cell\| PubMed ID: 21070967	2010
Translation by remote control. Cell\| PubMed ID: 21074041	2010
A pause to splice. Molecular cell\| PubMed ID: 21095579	2010
The eukaryotic RNA exosome: same scaffold but variable catalytic subunits. RNA biology\| PubMed ID: 21289487	2011
T-body formation precedes virus-like particle maturation in S. cerevisiae. RNA biology\| PubMed ID: 21358276	2011
PROMoter uPstream Transcripts share characteristics with mRNAs and are produced upstream of all three major types of mammalian promoters. Nucleic acids research\| PubMed ID: 21596787	2011
RNA exosome. Preface. Advances in experimental medicine and biology\| PubMed ID: 21618869	2010
Interaction profiling identifies the human nuclear exosome targeting complex. Molecular cell\| PubMed ID: 21855801	2011
Implication of Ccr4-Not complex function in mRNA quality control in Saccharomyces cerevisiae. RNA (New York, N.Y.)\| PubMed ID: 21862638	2011
Nuclear quality control of RNA polymerase II transcripts. Wiley interdisciplinary reviews. RNA\| PubMed ID: 21956943	2010
Saccharomyces cerevisiae Ngl3p is an active 3'-5' exonuclease with a specificity towards poly-A RNA reminiscent of cellular deadenylases. Nucleic acids research\| PubMed ID: 21965533	2012
Improved methodology for the affinity isolation of human protein complexes expressed at near endogenous levels. BioTechniques\| PubMed ID: 22668517	2012
Rrp6p controls mRNA poly(A) tail length and its decoration with poly(A) binding proteins. Molecular cell\| PubMed ID: 22683267	2012
Nuclear retention prevents premature cytoplasmic appearance of mRNA. Molecular cell\| PubMed ID: 22921936	2012
Transcription-associated quality control of mRNP. Biochimica et biophysica acta\| PubMed ID: 22982197	2013
Promoter-proximal polyadenylation sites reduce transcription activity. Genes & development\| PubMed ID: 23028143	2012
MRN1 implicates chromatin remodeling complexes and architectural factors in mRNA maturation. PloS one\| PubMed ID: 23028530	2012
Making ends meet: coordination between RNA 3'-end processing and transcription initiation. Wiley interdisciplinary reviews. RNA\| PubMed ID: 23450686	2013
Exonuclease hDIS3L2 specifies an exosome-independent 3'-5' degradation pathway of human cytoplasmic mRNA. The EMBO journal\| PubMed ID: 23756462	2013
Polyadenylation site-induced decay of upstream transcripts enforces promoter directionality. Nature structural & molecular biology\| PubMed ID: 23851456	2013
Mutational analysis of the yeast RNA helicase Sub2p reveals conserved domains required for growth, mRNA export, and genomic stability. RNA (New York, N.Y.)\| PubMed ID: 23962665	2013
Dealing with pervasive transcription. Molecular cell\| PubMed ID: 24267449	2013
The human cap-binding complex is functionally connected to the nuclear RNA exosome. Nature structural & molecular biology\| PubMed ID: 24270879	2013
Rat1p maintains RNA polymerase II CTD phosphorylation balance. RNA (New York, N.Y.)\| PubMed ID: 24501251	2014
SnapShot: nuclear RNAPII transcript modification. Cell\| PubMed ID: 24855955	2014
Human nonsense-mediated RNA decay initiates widely by endonucleolysis and targets snoRNA host genes. Genes & development\| PubMed ID: 25403180	2014
The human nuclear exosome targeting complex is loaded onto newly synthesized RNA to direct early ribonucleolysis. Cell reports\| PubMed ID: 25578728	2015
Rapid, optimized interactomic screening. Nature methods\| PubMed ID: 25938370	2015
The Nuclear PolyA-Binding Protein Nab2p Is Essential for mRNA Production. Cell reports\| PubMed ID: 26119729	2015
Nonsense-mediated mRNA decay: an intricate machinery that shapes transcriptomes. Nature reviews. Molecular cell biology\| PubMed ID: 26397022	2015
Human Gene Promoters Are Intrinsically Bidirectional. Molecular cell\| PubMed ID: 26545074	2015
Relationships between PROMPT and gene expression. RNA biology\| PubMed ID: 26574648	2016
Biochemistry and Function of RNA Exosomes. The Enzymes\| PubMed ID: 27166438	2012
Purification and analysis of endogenous human RNA exosome complexes. RNA (New York, N.Y.)\| PubMed ID: 27402899	2016
Principles for RNA metabolism and alternative transcription initiation within closely spaced promoters. Nature genetics\| PubMed ID: 27455346	2016
A conserved virus-induced cytoplasmic TRAMP-like complex recruits the exosome to target viral RNA for degradation. Genes & development\| PubMed ID: 27474443	2016
Identification of a Nuclear Exosome Decay Pathway for Processed Transcripts. Molecular cell\| PubMed ID: 27871484	2016
Structure of the RBM7-ZCCHC8 core of the NEXT complex reveals connections to splicing factors. Nature communications\| PubMed ID: 27905398	2016
Lariat capping as a tool to manipulate the 5' end of individual yeast mRNA species in vivo. RNA (New York, N.Y.)\| PubMed ID: 28159804	2017
Nuclear Decay Factors Crack Up mRNA. Molecular cell\| PubMed ID: 28257696	2017
Mutually Exclusive CBC-Containing Complexes Contribute to RNA Fate. Cell reports\| PubMed ID: 28297668	2017
Targeting the nuclear RNA exosome: Poly(A) binding proteins enter the stage. RNA biology\| PubMed ID: 28421898	2017
Characterising -regulatory variation in the transcriptome of histologically normal and tumour-derived pancreatic tissues. Gut\| PubMed ID: 28634199	2018
Polo-like kinase 2 modulates α-synuclein protein levels by regulating its mRNA production. Neurobiology of disease\| PubMed ID: 28648742	2017
ARS2 is a general suppressor of pervasive transcription. Nucleic acids research\| PubMed ID: 28973446	2017
Characterizing ZC3H18, a Multi-domain Protein at the Interface of RNA Production and Destruction Decisions. Cell reports\| PubMed ID: 29298432	2018
Transcription start site analysis reveals widespread divergent transcription in D. melanogaster and core promoter-encoded enhancer activities. Nucleic acids research\| PubMed ID: 29659982	2018
Controlling nuclear RNA levels. Nature reviews. Genetics\| PubMed ID: 29748575	2018
The RNA Exosome Adaptor ZFC3H1 Functionally Competes with Nuclear Export Activity to Retain Target Transcripts. Cell reports\| PubMed ID: 29768216	2018
Diminished nuclear RNA decay upon infection upregulates antibacterial noncoding RNAs. The EMBO journal\| PubMed ID: 29880601	2018
A Nuclear Export Block Triggers the Decay of Newly Synthesized Polyadenylated RNA. Cell reports\| PubMed ID: 30157437	2018
Simultaneous Measurement of Transcriptional and Post-transcriptional Parameters by 3' End RNA-Seq. Cell reports\| PubMed ID: 30157438	2018
The RNA exosome contributes to gene expression regulation during stem cell differentiation. Nucleic acids research\| PubMed ID: 30212902	2018
Box C/D snoRNP Autoregulation by a cis-Acting snoRNA in the NOP56 Pre-mRNA. Molecular cell\| PubMed ID: 30220559	2018
The multitasking polyA tail: nuclear RNA maturation, degradation and export. Philosophical transactions of the Royal Society of London. Series B, Biological sciences\| PubMed ID: 30397105	2018
Escaping nuclear decay: the significance of mRNA export for gene expression. Current genetics\| PubMed ID: 30515529	2019
Preparation of RNA 3' End Sequencing Libraries of Total and 4-thiouracil Labeled RNA for Simultaneous Measurement of Transcription, RNA Synthesis and Decay in . Bio-protocol\| PubMed ID: 30931349	2019
The MTR4 helicase recruits nuclear adaptors of the human RNA exosome using distinct arch-interacting motifs. Nature communications\| PubMed ID: 31358741	2019
The long noncoding RNA is seemingly dispensable for normal tissue homeostasis and cancer cell growth. RNA (New York, N.Y.)\| PubMed ID: 31551298	2019
Nuclear sorting of RNA. Wiley interdisciplinary reviews. RNA\| PubMed ID: 31713323	2020
A Functional Link between Nuclear RNA Decay and Transcriptional Control Mediated by the Polycomb Repressive Complex 2. Cell reports\| PubMed ID: 31722198	2019
Global Identification of Human Exosome Substrates Using RNA Interference and RNA Sequencing. Methods in molecular biology (Clifton, N.J.)\| PubMed ID: 31768975	2020
The Nuclear RNA Exosome and Its Cofactors. Advances in experimental medicine and biology\| PubMed ID: 31811632	2019
The human ZC3H3 and RBM26/27 proteins are critical for PAXT-mediated nuclear RNA decay. Nucleic acids research\| PubMed ID: 31950173	2020
A Two-Layered Targeting Mechanism Underlies Nuclear RNA Sorting by the Human Exosome. Cell reports\| PubMed ID: 32075771	2020