Mikko Airavaara

Neuroscience Center, University of Helsinki

Research Area

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title Cited by 15	2020

Other Publications

Article	Year
Increased extracellular dopamine concentrations and FosB/DeltaFosB expression in striatal brain areas of heterozygous GDNF knockout mice. The European journal of neuroscience\| PubMed ID: 15525275	2004
In heterozygous GDNF knockout mice the response of striatal dopaminergic system to acute morphine is altered. Synapse (New York, N.Y.)\| PubMed ID: 16437537	2006
Effects of repeated morphine on locomotion, place preference and dopamine in heterozygous glial cell line-derived neurotrophic factor knockout mice. Genes, brain, and behavior\| PubMed ID: 16879618	2007
Constitutive Ret activity in knock-in multiple endocrine neoplasia type B mice induces profound elevation of brain dopamine concentration via enhanced synthesis and increases the number of T... The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 17475787	2007
Characterization of the striatal dopaminergic neurotransmission in MEN2B mice with elevated cerebral tissue dopamine. Journal of neurochemistry\| PubMed ID: 18248620	2008
Chronic nicotine modifies the effects of morphine on extracellular striatal dopamine and ventral tegmental GABA. Journal of neurochemistry\| PubMed ID: 18786163	2008
WITHDRAWN: Neurorestoration. Parkinsonism & related disorders\| PubMed ID: 21924941	2011
CDNF protects the nigrostriatal dopamine system and promotes recovery after MPTP treatment in mice. Cell transplantation\| PubMed ID: 21943517	2012
Neurorestoration. Parkinsonism & related disorders\| PubMed ID: 22166416	2012
Mesencephalic astrocyte-derived neurotrophic factor (MANF) secretion and cell surface binding are modulated by KDEL receptors. The Journal of biological chemistry\| PubMed ID: 23255601	2013
Local administration of AAV-BDNF to subventricular zone induces functional recovery in stroke rats. PloS one\| PubMed ID: 24312581	2013
Short-term preoperative dietary restriction is neuroprotective in a rat focal stroke model. PloS one\| PubMed ID: 24705386	2014
AAV-mediated targeting of gene expression to the peri-infarct region in rat cortical stroke model. Journal of neuroscience methods\| PubMed ID: 25152446	2014
Prospects of Neurotrophic Factors for Parkinson's Disease: Comparison of Protein and Gene Therapy. Human gene therapy\| PubMed ID: 26176331	2015
Therapeutic potential of the endoplasmic reticulum located and secreted CDNF/MANF family of neurotrophic factors in Parkinson's disease. FEBS letters\| PubMed ID: 26450777	2015
Characterization of a new low-dose 6-hydroxydopamine model of Parkinson's disease in rat. Journal of neuroscience research\| PubMed ID: 26762168	2016
Oral hypoglycaemic effect of GLP-1 and DPP4 inhibitor based nanocomposites in a diabetic animal model. Journal of controlled release : official journal of the Controlled Release Society\| PubMed ID: 27091697	2016
Update of neurotrophic factors in neurobiology of addiction and future directions. Neurobiology of disease\| PubMed ID: 27189755	2017
Role of microglia in ischemic focal stroke and recovery: focus on Toll-like receptors. Progress in neuro-psychopharmacology & biological psychiatry\| PubMed ID: 27389423	2017
Developing therapeutically more efficient Neurturin variants for treatment of Parkinson's disease. Neurobiology of disease\| PubMed ID: 27425888	2016
Accumbal μ-Opioid Receptors Modulate Ethanol Intake in Alcohol-Preferring Alko Alcohol Rats. Alcoholism, clinical and experimental research\| PubMed ID: 27508965	2016
AAV Vector-Mediated Gene Delivery to Substantia Nigra Dopamine Neurons: Implications for Gene Therapy and Disease Models. Genes\| PubMed ID: 28208742	2017
Intrastriatally Infused Exogenous CDNF Is Endocytosed and Retrogradely Transported to Substantia Nigra. eNeuro\| PubMed ID: 28275710	2017
Nigral injection of a proteasomal inhibitor, lactacystin, induces widespread glial cell activation and shows various phenotypes of Parkinson's disease in young and adult mouse. Experimental brain research\| PubMed ID: 28439627	2017
9-cis retinoic acid induces neurorepair in stroke brain. Scientific reports\| PubMed ID: 28674431	2017
Multifunctional Nanotube-Mucoadhesive Poly(methyl vinyl ether-co-maleic acid)@Hydroxypropyl Methylcellulose Acetate Succinate Composite for Site-Specific Oral Drug Delivery. Advanced healthcare materials\| PubMed ID: 28714596	2017
MANF Promotes Differentiation and Migration of Neural Progenitor Cells with Potential Neural Regenerative Effects in Stroke. Molecular therapy : the journal of the American Society of Gene Therapy\| PubMed ID: 29050872	2018
MANF Is Essential for Neurite Extension and Neuronal Migration in the Developing Cortex. eNeuro\| PubMed ID: 29082311	2017
Development and plasticity of meningeal lymphatic vessels. The Journal of experimental medicine\| PubMed ID: 29141865	2017
Combination of CDNF and Deep Brain Stimulation Decreases Neurological Deficits in Late-stage Model Parkinson's Disease. Neuroscience\| PubMed ID: 29408408	2018
Differential Spinal and Supraspinal Activation of Glia in a Rat Model of Morphine Tolerance. Neuroscience\| PubMed ID: 29421434	2018
The κ-opioid receptor antagonist JDTic decreases ethanol intake in alcohol-preferring AA rats. Psychopharmacology\| PubMed ID: 29492614	2018
Towards developing a model to study alcohol drinking and craving in female mice housed in automated cages. Behavioural brain research\| PubMed ID: 29572104	2018
Synthesis of 7β-hydroxy-8-ketone opioid derivatives with antagonist activity at mu- and delta-opioid receptors. European journal of medicinal chemistry\| PubMed ID: 29649744	2018
Post-stroke Intranasal (+)-Naloxone Delivery Reduces Microglial Activation and Improves Behavioral Recovery from Ischemic Injury. eNeuro\| PubMed ID: 29766045	2018
Poststroke delivery of MANF promotes functional recovery in rats. Science advances\| PubMed ID: 29806020	2018
Pre-α-pro-GDNF and Pre-β-pro-GDNF Isoforms Are Neuroprotective in the 6-hydroxydopamine Rat Model of Parkinson's Disease. Frontiers in neurology\| PubMed ID: 29973907	2018
Implementation of deep neural networks to count dopamine neurons in substantia nigra. The European journal of neuroscience\| PubMed ID: 30144349	2018
Downregulation of tyrosine hydroxylase phenotype after AAV injection above substantia nigra: Caution in experimental models of Parkinson's disease. Journal of neuroscience research\| PubMed ID: 30548446	2019
Neuron-Specific Genome Modification in the Adult Rat Brain Using CRISPR-Cas9 Transgenic Rats. Neuron\| PubMed ID: 30792150	2019
Secondary Pathology of the Thalamus after Focal Cortical Stroke in Rats is not Associated with Thermal or Mechanical Hypersensitivity and is Not Alleviated by Intra-Thalamic Post-Stroke Deli... Cell transplantation\| PubMed ID: 31037983	2019
Neuroprotective and reparative effects of endoplasmic reticulum luminal proteins - mesencephalic astrocyte-derived neurotrophic factor and cerebral dopamine neurotrophic factor. Croatian medical journal\| PubMed ID: 31044581	2019
Effects of Neurotrophic Factors in Glial Cells in the Central Nervous System: Expression and Properties in Neurodegeneration and Injury. Frontiers in physiology\| PubMed ID: 31105589	2019
Cerebral Dopamine Neurotrophic Factor Diffuses Around the Brainstem and Does Not Undergo Anterograde Transport After Injection to the Substantia Nigra. Frontiers in neuroscience\| PubMed ID: 31244598	2019
Neuronal Activation Stimulates Cytomegalovirus Promoter-Driven Transgene Expression. Molecular therapy. Methods & clinical development\| PubMed ID: 31380464	2019
Engineered antibody-functionalized porous silicon nanoparticles for therapeutic targeting of pro-survival pathway in endogenous neuroblasts after stroke. Biomaterials\| PubMed ID: 31670035	2020
Cerebral dopamine neurotrophic factor-deficiency leads to degeneration of enteric neurons and altered brain dopamine neuronal function in mice. Neurobiology of disease\| PubMed ID: 31783118	2020
MANF Ablation Causes Prolonged Activation of the UPR without Neurodegeneration in the Mouse Midbrain Dopamine System. eNeuro\| PubMed ID: 32005751	2020
Back and to the Future: From Neurotoxin-Induced to Human Parkinson's Disease Models. Current protocols in neuroscience\| PubMed ID: 32049438	2020
Molecular profile of the rat peri-infarct region four days after stroke: Study with MANF. Experimental neurology\| PubMed ID: 32229226	2020
Mitoxantrone, pixantrone and mitoxantrone (2-hydroxyethyl)piperazine are toll-like receptor 4 antagonists, inhibit NF-κB activation, and decrease TNF-alpha secretion in primary microglia. European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences\| PubMed ID: 32730846	2020