Andrii Domanskyi

Andrii Domanskyi

Institute of Biotechnology, University of Helsinki

Affiliated withUniversity of Helsinki

Research Area

Biography

Dr. Andrii Domanskyi is a Principal Investigator and a research group leader at the Institute of Biotechnology, University of Helsinki. He received his undergraduate with honors degree from Moscow Institute of Physics and Technology, and a PhD from the University of Helsinki, Finland.

Dr. Domanskyi main research interest is finding novel neuroprotective strategies combining neurotrophic factors, drugs and non-coding RNAs targeting specific pro-survival cellular pathways. His interest in molecular neuroscience started during post-doctoral work in Prof. Günther Schütz’s lab at the German Cancer Research Institute (DKFZ) in Heidelberg, where he moved after receiving PhD from the Faculty of Medicine, University of Helsinki. As a post-doctoral scientist at DKFZ Heidelberg, he used in vivo tissue-specific inducible transgenic mouse models to study pro-survival pathways in adult dopaminergic neurons.

In 2014 Dr. Domanskyi returned to Finland as a senior post-doctoral scientist in a Business Finland-funded 3iRegeneration project to study neural stem cells, transcription factors, and neurotrophic factors in models of Parkinson’s disease. During his training at Optogenetics and Transgenic Technology Core facility at the National Institute on Drug Abuse (NIDA), USA, he gained expertise in modern tools for somatic transgenesis and in vivo gene editing (CRISPR-Cas9), and development of reporter systems for drug discovery.

In 2015 Dr. Domanskyi received the Academy of Finland Research Fellowship and established a research group at the Institute of Biotechnology, University of Helsinki.

JoVE Journal Publications

ArticleTotal : 1
Year
Studying Pre-formed Fibril Induced α-Synuclein Accumulation in Primary Embryonic Mouse Midbrain Dopamine Neurons
Publication title

Cited by 15

2020

Other Publications

Article
Year
Biochemical characterization of androgen receptor-interacting protein 4.

The Biochemical journal| PubMed ID: 16212558

2006
Expression and localization of androgen receptor-interacting protein-4 in the testis.

American journal of physiology. Endocrinology and metabolism| PubMed ID: 17003240

2007
2007
2015
2017
2017
2017
Dicer and microRNAs protect adult dopamine neurons.

Cell death & disease| PubMed ID: 28542144

2017
2017
MANF Promotes Differentiation and Migration of Neural Progenitor Cells with Potential Neural Regenerative Effects in Stroke.

Molecular therapy : the journal of the American Society of Gene Therapy| PubMed ID: 29050872

2018
2017
2017
2018
2019
2019
2019
2020
Interplay between MicroRNAs and Oxidative Stress in Neurodegenerative Diseases.

International journal of molecular sciences| PubMed ID: 31801298

2019
2020
2020