Rolf Kaiser

Institute of Virology, University of Cologne

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title Cited by 16	2011

Other Publications

Article	Year
Correlation between serotonin uptake in human blood platelets with the 44-bp polymorphism and the 17-bp variable number of tandem repeat of the serotonin transporter. American journal of medical genetics\| PubMed ID: 11920857	2002
Simultaneous determination of ondansetron and tropisetron in human plasma using HPLC with UV detection. Biomedical chromatography : BMC\| PubMed ID: 11920943	2002
Validity of PCR with emphasis on variable number of tandem repeat analysis. Clinical biochemistry\| PubMed ID: 11937078	2002
Efficacy and safety of abacavir plus efavirenz as a salvage regimen in HIV-infected individuals after 48 weeks. AIDS (London, England)\| PubMed ID: 11953478	2002
Diversity and complexity of HIV-1 drug resistance: a bioinformatics approach to predicting phenotype from genotype. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 12060770	2002
Patient-tailored antiemetic treatment with 5-hydroxytryptamine type 3 receptor antagonists according to cytochrome P-450 2D6 genotypes. Journal of clinical oncology : official journal of the American Society of Clinical Oncology\| PubMed ID: 12065557	2002
Risk of hepatitis C after immunoadsorption. Infection control and hospital epidemiology : the official journal of the Society of Hospital Epidemiologists of America\| PubMed ID: 12083240	2002
Frequency of the 17-bp variable number of tandem repeat polymorphism in Turkish schizophrenic patients. Schizophrenia research\| PubMed ID: 12363397	2002
Variations in the 5-hydroxytryptamine type 3B receptor gene as predictors of the efficacy of antiemetic treatment in cancer patients. Journal of clinical oncology : official journal of the American Society of Clinical Oncology\| PubMed ID: 12775740	2003
Geno2pheno: Estimating phenotypic drug resistance from HIV-1 genotypes. Nucleic acids research\| PubMed ID: 12824435	2003
Methods for optimizing antiviral combination therapies. Bioinformatics (Oxford, England)\| PubMed ID: 12855433	2003
Tenofovir resistance and resensitization. Antimicrobial agents and chemotherapy\| PubMed ID: 14576105	2003
Variations in the genes encoding the peroxisome proliferator-activated receptors alpha and gamma in psoriasis. Archives of dermatological research\| PubMed ID: 15083308	2004
Meta-analysis of the dopamine D3 receptor gene (DRD3) Ser9Gly variant and schizophrenia. Psychiatric genetics\| PubMed ID: 15091310	2004
Investigation of the association between 5-HT3A receptor gene polymorphisms and efficiency of antiemetic treatment with 5-HT3 receptor antagonists. Pharmacogenetics\| PubMed ID: 15115912	2004
Pharmacogenetics-based new therapeutic concepts. Drug metabolism reviews\| PubMed ID: 15554239	2004
Successful therapy of hepatitis B with tenofovir in HIV-infected patients failing previous adefovir and lamivudine treatment. AIDS (London, England)\| PubMed ID: 15577546	2004
Mtreemix: a software package for learning and using mixture models of mutagenetic trees. Bioinformatics (Oxford, England)\| PubMed ID: 15657098	2005
Estimating HIV evolutionary pathways and the genetic barrier to drug resistance. The Journal of infectious diseases\| PubMed ID: 15871130	2005
Antiemetic guidelines: are they being used? The lancet oncology\| PubMed ID: 16054573	2005
Comparison of GB virus C, HIV, and HCV infection markers in hemophiliacs exposed to non-inactivated or inactivated factor concentrates. Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology\| PubMed ID: 16087123	2005
Learning multiple evolutionary pathways from cross-sectional data. Journal of computational biology : a journal of computational molecular cell biology\| PubMed ID: 16108705	2005
Computational methods for the design of effective therapies against drug resistant HIV strains. Bioinformatics (Oxford, England)\| PubMed ID: 16144807	2005
Evolution of HIV resistance during treatment interruption in experienced patients and after restarting a new therapy. Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology\| PubMed ID: 16191482	2005
Basics of the virology of HIV-1 and its replication. Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology\| PubMed ID: 16198625	2005
Bioinformatics approach to predicting HIV drug resistance. Expert review of molecular diagnostics\| PubMed ID: 16512780	2006
Primary HIV drug resistance and efficacy of first-line antiretroviral therapy guided by resistance testing. Journal of acquired immune deficiency syndromes (1999)\| PubMed ID: 16652031	2006
Variations in the peroxisome proliferator-activated receptor-gamma gene and melanoma risk. Cancer letters\| PubMed ID: 16713673	2007
Detection of bocavirus DNA in nasopharyngeal aspirates of a child with bronchiolitis. The Journal of infection\| PubMed ID: 16968654	2007
Stable coreceptor usage of HIV in patients with ongoing treatment failure on HAART. Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology\| PubMed ID: 17005445	2006
Functional domains of the human immunodeficiency virus type 1 Nef protein are conserved among different clades in Cameroon. AIDS research and human retroviruses\| PubMed ID: 17067262	2006
Variations of the melanocortin-1 receptor and the glutathione-S transferase T1 and M1 genes in cutaneous malignant melanoma. Archives of dermatological research\| PubMed ID: 17072629	2007
Reactivation of an occult hepatitis B virus escape mutant in an anti-HBs positive, anti-HBc negative lymphoma patient. Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology\| PubMed ID: 17134939	2007
Severe pneumonia and human bocavirus in adult. Emerging infectious diseases\| PubMed ID: 17176591	2006
Compensatory mutations at the HIV cleavage sites p7/p1 and p1/p6-gag in therapy-naive and therapy-experienced patients. Antiviral therapy\| PubMed ID: 17302250	2006
A novel internally controlled real-time reverse transcription-PCR assay for HIV-1 RNA targeting the pol integrase genomic region. Journal of virological methods\| PubMed ID: 17321607	2007
Improved prediction of response to antiretroviral combination therapy using the genetic barrier to drug resistance. Antiviral therapy\| PubMed ID: 17503659	2007
Genetic polymorphisms in the amino acid transporters LAT1 and LAT2 in relation to the pharmacokinetics and side effects of melphalan. Pharmacogenetics and genomics\| PubMed ID: 17558306	2007
Frequent detection of cell-associated HIV-1 RNA in patients with plasma viral load <50 copies/ml. Journal of medical virology\| PubMed ID: 17705170	2007
Trends of prevalence of primary HIV drug resistance in Germany. The Journal of antimicrobial chemotherapy\| PubMed ID: 17715124	2007
Selective pressures of HLA genotypes and antiviral therapy on human immunodeficiency virus type 1 sequence mutation at a population level. Clinical and vaccine immunology : CVI\| PubMed ID: 17715334	2007
Fifteen years of env C2V3C3 evolution in six individuals infected clonally with human immunodeficiency virus type 1. Journal of medical virology\| PubMed ID: 17854039	2007
Predicting HIV coreceptor usage on the basis of genetic and clinical covariates. Antiviral therapy\| PubMed ID: 18018768	2007
Bioinformatics prediction of HIV coreceptor usage. Nature biotechnology\| PubMed ID: 18066037	2007
Functional characterization of a -100_-102delAAG deletion-insertion polymorphism in the promoter region of the HTR3B gene. Pharmacogenetics and genomics\| PubMed ID: 18300944	2008
Serotonin transporter gene and response to lithium augmentation in depression. Psychiatric genetics\| PubMed ID: 18349701	2008
Selecting anti-HIV therapies based on a variety of genomic and clinical factors. Bioinformatics (Oxford, England)\| PubMed ID: 18586740	2008
Comparison of classifier fusion methods for predicting response to anti HIV-1 therapy. PloS one\| PubMed ID: 18941628	2008
Genotypic antiretroviral resistance testing for human immunodeficiency virus type 1 integrase inhibitors by use of the TruGene sequencing system. Journal of clinical microbiology\| PubMed ID: 18945845	2008
Phase I dose escalation and pharmacokinetic study of BI 2536, a novel Polo-like kinase 1 inhibitor, in patients with advanced solid tumors. Journal of clinical oncology : official journal of the American Society of Clinical Oncology\| PubMed ID: 18955456	2008
Prevalence of C-terminal gag cleavage site mutations in HIV from therapy-naÃ¯ve patients. The Journal of infection\| PubMed ID: 19110315	2009
Predicting the response to combination antiretroviral therapy: retrospective validation of geno2pheno-THEO on a large clinical database. The Journal of infectious diseases\| PubMed ID: 19239365	2009
Prevalence of minor variants of HIV strains at reverse transcriptase position 103 in therapy-naÃ¯ve patients and their impact on the virological failure. Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology\| PubMed ID: 19375978	2009
Advantages of predicted phenotypes and statistical learning models in inferring virological response to antiretroviral therapy from HIV genotype. Antiviral therapy\| PubMed ID: 19430102	2009
Evolution of raltegravir resistance during therapy. The Journal of antimicrobial chemotherapy\| PubMed ID: 19447792	2009
Kinetic binding analysis of aptamers targeting HIV-1 proteins by a combination of a microbalance array and mass spectrometry (MAMS). Journal of proteome research\| PubMed ID: 19469583	2009
[Resistance screening]. MMW Fortschritte der Medizin\| PubMed ID: 19769083	2009
Seasonal influenza virus species in patient swab samples analyzed for the presence of the pandemic (H1N1) 2009 influenza virus. Journal of clinical microbiology\| PubMed ID: 19794039	2009
V3 loop sequence space analysis suggests different evolutionary patterns of CCR5- and CXCR4-tropic HIV. PloS one\| PubMed ID: 19816596	2009
When and how to use maraviroc in HIV-infected patients. AIDS (London, England)\| PubMed ID: 19834318	2009
High prevalence of bevirimat resistance mutations in protease inhibitor-resistant HIV isolates. AIDS (London, England)\| PubMed ID: 19926962	2010
Phase I study of the angiogenesis inhibitor BIBF 1120 in patients with advanced solid tumors. Clinical cancer research : an official journal of the American Association for Cancer Research\| PubMed ID: 20028771	2010
The evolution of protease mutation 76V is associated with protease mutation 46I and gag mutation 431V. AIDS (London, England)\| PubMed ID: 20139751	2010
Only slight impact of predicted replicative capacity for therapy response prediction. PloS one\| PubMed ID: 20140263	2010
Short communication: selection of thymidine analogue resistance mutational patterns in children infected from a common HIV type 1 subtype G source. AIDS research and human retroviruses\| PubMed ID: 20334563	2010
Evolution of protease inhibitor resistance in the gag and pol genes of HIV subtype G isolates. The Journal of antimicrobial chemotherapy\| PubMed ID: 20430786	2010
Phase I open-label study of continuous treatment with BIBF 1120, a triple angiokinase inhibitor, and pemetrexed in pretreated non-small cell lung cancer patients. Clinical cancer research : an official journal of the American Association for Cancer Research\| PubMed ID: 20460487	2010
Phase I safety, pharmacokinetic, and biomarker study of BIBF 1120, an oral triple tyrosine kinase inhibitor in patients with advanced solid tumors. Molecular cancer therapeutics\| PubMed ID: 20688946	2010
Analysis of immune selection as a potential cause for the presence of cleavage site mutation 431V in treatment-naive HIV type-1 isolates. Antiviral therapy\| PubMed ID: 20834103	2010
Prevalence and characteristics of hepatitis B and C virus infections in treatment-naÃ¯ve HIV-infected patients. Medical microbiology and immunology\| PubMed ID: 20853118	2011
Improved prediction of HIVâ€1 coreceptor usage with sequence information from the second hypervariable loop of gp120. The Journal of infectious diseases\| PubMed ID: 20874088	2010
Hepatitis B virus reverse transcriptase sequence variant database for sequence analysis and mutation discovery. Antiviral research\| PubMed ID: 20875460	2010
Characterisation of the epitope for a herpes simplex virus glycoprotein B-specific monoclonal antibody with high protective capacity. Medical microbiology and immunology\| PubMed ID: 20931340	2011
Prevalence of key resistance mutations K65R, K103N, and M184V as minority HIV-1 variants in chronically HIV-1 infected, treatment-naÃ¯ve patients. Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology\| PubMed ID: 21056001	2011
Antiretroviral therapy optimisation without genotype resistance testing: a perspective on treatment history based models. PloS one\| PubMed ID: 21060792	2010
Influence of major HIV-1 protease inhibitor resistance mutations on CTL recognition. Journal of acquired immune deficiency syndromes (1999)\| PubMed ID: 21107269	2011
Changes in the HIV-1 mutational profile before first-line HAART in the RESINA cohort. Journal of medical virology\| PubMed ID: 21181911	2011
Pharmacokinetics and metabolism of BIBF 1120 after oral dosing to healthy male volunteers. Xenobiotica; the fate of foreign compounds in biological systems\| PubMed ID: 21204634	2011
The L76V mutation in HIV-1 protease is potentially associated with hypersusceptibility to protease inhibitors Atazanavir and Saquinavir: is there a clinical advantage? AIDS research and therapy\| PubMed ID: 21314993	2011
Treatment of lung cancer patients and concomitant use of drugs interacting with cytochrome P450 isoenzymes. Lung cancer (Amsterdam, Netherlands)\| PubMed ID: 21382644	2011
HIV prevalence and route of transmission in Turkish immigrants living in North-Rhine Westphalia, Germany. Medical microbiology and immunology\| PubMed ID: 21461764	2011
The SnoB study: frequency of baseline raltegravir resistance mutations prevalence in different non-B subtypes. Medical microbiology and immunology\| PubMed ID: 21475993	2011
Genotypic tropism testing by massively parallel sequencing: qualitative and quantitative analysis. BMC medical informatics and decision making\| PubMed ID: 21569501	2011
APOBEC3G/F as one possible driving force for co-receptor switch of the human immunodeficiency virus-1. Medical microbiology and immunology\| PubMed ID: 21573951	2012
Detection of drug resistance mutations at low plasma HIV-1 RNA load in a European multicentre cohort study. The Journal of antimicrobial chemotherapy\| PubMed ID: 21624929	2011
Severe human bocavirus infection, Germany. Emerging infectious diseases\| PubMed ID: 22172367	2011
Mutational patterns in the frameshift-regulating site of HIV-1 selected by protease inhibitors. Medical microbiology and immunology\| PubMed ID: 22200908	2011
Endogenous or exogenous spreading of HIV-1 in Nordrhein-Westfalen, Germany, investigated by phylodynamic analysis of the RESINA Study cohort. Medical microbiology and immunology\| PubMed ID: 22262052	2012
HIV-GRADE: A Publicly Available, Rules-Based Drug Resistance Interpretation Algorithm Integrating Bioinformatic Knowledge. Intervirology\| PubMed ID: 22286877	2012
Predicting Response to Antiretroviral Treatment by Machine Learning: The EuResist Project. Intervirology\| PubMed ID: 22286881	2012
Risk Factors Associated with Older Age in Treatment-Naive HIV-Positive Patients. Intervirology\| PubMed ID: 22286885	2012
Epidemiology of Transmitted Drug Resistance in Chronically HIV-Infected Patients in Germany: The RESINA Study 2001-2009. Intervirology\| PubMed ID: 22286886	2012
Efficacy of Antiretroviral Therapy Switch in HIV-Infected Patients: A 10-Year Analysis of the EuResist Cohort. Intervirology\| PubMed ID: 22286887	2012
How Individual Can Personalized Antiretroviral Treatment Be? Deep Salvage in an HIV-1-Infected Patient. Intervirology\| PubMed ID: 22286888	2012