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Alexander Thielen

Max Planck Institute for Informatics

Affiliated withMax Planck Institute for Informatics

Research Area

Immunology and Infection

Biography

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title Cited by 16	2011

Other Publications

Article	Year
Bioinformatics prediction of HIV coreceptor usage. Nature biotechnology\| PubMed ID: 18066037	2007
V3 loop sequence space analysis suggests different evolutionary patterns of CCR5- and CXCR4-tropic HIV. PloS one\| PubMed ID: 19816596	2009
Decreased HIV diversity after allogeneic stem cell transplantation of an HIV-1 infected patient: a case report. Virology journal\| PubMed ID: 20210988	2010
Improved detection of CXCR4-using HIV by V3 genotyping: application of population-based and "deep" sequencing to plasma RNA and proviral DNA. Journal of acquired immune deficiency syndromes (1999)\| PubMed ID: 20512044	2010
Population-based V3 genotypic tropism assay: a retrospective analysis using screening samples from the A4001029 and MOTIVATE studies. AIDS (London, England)\| PubMed ID: 20736814	2010
Improved prediction of HIVâ€1 coreceptor usage with sequence information from the second hypervariable loop of gp120. The Journal of infectious diseases\| PubMed ID: 20874088	2010
Dynamic escape of pre-existing raltegravir-resistant HIV-1 from raltegravir selection pressure. Antiviral research\| PubMed ID: 20883724	2010
In-depth analysis of G-to-A hypermutation rate in HIV-1 env DNA induced by endogenous APOBEC3 proteins using massively parallel sequencing. Journal of virological methods\| PubMed ID: 21111003	2011
Deep sequencing to infer HIV-1 co-receptor usage: application to three clinical trials of maraviroc in treatment-experienced patients. The Journal of infectious diseases\| PubMed ID: 21288824	2011
Mutations in gp41 are correlated with coreceptor tropism but do not improve prediction methods substantially. Antiviral therapy\| PubMed ID: 21555814	2011
Genotypic tropism testing by massively parallel sequencing: qualitative and quantitative analysis. BMC medical informatics and decision making\| PubMed ID: 21569501	2011
APOBEC3G/F as one possible driving force for co-receptor switch of the human immunodeficiency virus-1. Medical microbiology and immunology\| PubMed ID: 21573951	2012
Added value of deep sequencing relative to population sequencing in heavily pre-treated HIV-1-infected subjects. PloS one\| PubMed ID: 21602929	2011
High concordance between the position-specific scoring matrix and geno2pheno algorithms for genotypic interpretation of HIV-1 tropism: V3 length as the major cause of disagreement. Journal of clinical microbiology\| PubMed ID: 21734029	2011
HIV-1 mutational pathways under multidrug therapy. AIDS research and therapy\| PubMed ID: 21794106	2011
Deep V3 sequencing for HIV type 1 tropism in treatment-naive patients: a reanalysis of the MERIT trial of maraviroc. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America\| PubMed ID: 21890778	2011
HIV-GRADE: A Publicly Available, Rules-Based Drug Resistance Interpretation Algorithm Integrating Bioinformatic Knowledge. Intervirology\| PubMed ID: 22286877	2012
Geno2pheno[454]: A Web Server for the Prediction of HIV-1 Coreceptor Usage from Next-Generation Sequencing Data. Intervirology\| PubMed ID: 22286879	2012