Rosalind A. Segal

Department of Pediatric Oncology, Dana Farber Cancer Institute

Affiliated withDana Farber Cancer Institute Harvard Medical School Dana-Farber Cancer Institute

Research Area

Biography

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JoVE Journal Publications

ArticleTotal : 2	Year
Publication title Cited by 20	2008
Publication title Cited by 29	2015

Other Publications

Article	Year
Brain-derived neurotrophic factor modulates cerebellar plasticity and synaptic ultrastructure. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 11850459	2002
Location, location, location: a spatial view of neurotrophin signal transduction. Trends in neurosciences\| PubMed ID: 11852149	2002
BDNF stimulates migration of cerebellar granule cells. Development (Cambridge, England)\| PubMed ID: 11880352	2002
小脑蛋白多糖在开发过程中调节声波刺猬的反应。 Development (Cambridge, England)\| PubMed ID: 11959830	2002
Retrograde neurotrophin signaling: Trk-ing along the axon. Current opinion in neurobiology\| PubMed ID: 12049932	2002
Medulloblastomas and primitive neuroectodermal tumors rarely contain polyomavirus DNA sequences. Neuro-oncology\| PubMed ID: 12084346	2002
High-resolution imaging demonstrates dynein-based vesicular transport of activated Trk receptors. Journal of neurobiology\| PubMed ID: 12150505	2002
Regional expression of p75NTR contributes to neurotrophin regulation of cerebellar patterning. Molecular and cellular neurosciences\| PubMed ID: 12595234	2003
Selectivity in neurotrophin signaling: theme and variations. Annual review of neuroscience\| PubMed ID: 12598680	2003
Growth, survival and migration: the Trk to cancer. Cancer treatment and research\| PubMed ID: 12613191	2003
Medulloblastoma tumorigenesis diverges from cerebellar granule cell differentiation in patched heterozygous mice. Developmental biology\| PubMed ID: 14568546	2003
A small-molecule antagonist of CXCR4 inhibits intracranial growth of primary brain tumors. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 14595012	2003
Dynein motors transport activated Trks to promote survival of target-dependent neurons. Nature neuroscience\| PubMed ID: 15122257	2004
Subtracting the Math: prominin-positive cerebellar stem cells in white matter. Nature neuroscience\| PubMed ID: 15917830	2005
Migration from a mitogenic niche promotes cell-cycle exit. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 16280582	2005
CXCR4 inhibition synergizes with cytotoxic chemotherapy in gliomas. Clinical cancer research : an official journal of the American Association for Cancer Research\| PubMed ID: 17121897	2006
Polarized signaling endosomes coordinate BDNF-induced chemotaxis of cerebellar precursors. Neuron\| PubMed ID: 17610817	2007
A neuron-specific cytoplasmic dynein isoform preferentially transports TrkB signaling endosomes. The Journal of cell biology\| PubMed ID: 18559670	2008
Action in the axon: generation and transport of signaling endosomes. Current opinion in neurobiology\| PubMed ID: 18778772	2008
Proteoglycan interactions with Sonic Hedgehog specify mitogenic responses. Nature neuroscience\| PubMed ID: 19287388	2009
A retrograde neuronal survival response: target-derived neurotrophins regulate MEF2D and bcl-w. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 19458239	2009
Anterograde transport of TrkB in axons is mediated by direct interaction with Slp1 and Rab27. Developmental cell\| PubMed ID: 19460344	2009
Live or let die: CCM2 provides the link. Neuron\| PubMed ID: 19755097	2009
The longer U(T)R, the further you go. Nature neuroscience\| PubMed ID: 20177416	2010
Sensory neuropathy attributable to loss of Bcl-w. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 21289171	2011
Neuromuscular junction defects in mice with mutation of dynein heavy chain 1. PloS one\| PubMed ID: 21346813	2011
Numb links extracellular cues to intracellular polarity machinery to promote chemotaxis. Developmental cell\| PubMed ID: 21571219	2011
From synapse to nucleus and back again--communication over distance within neurons. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 22072654	2011
Target-derived neurotrophins coordinate transcription and transport of bclw to prevent axonal degeneration. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 23516285	2013
Heparan sulfate proteoglycans containing a glypican 5 core and 2-O-sulfo-iduronic acid function as Sonic Hedgehog co-receptors to promote proliferation. The Journal of biological chemistry\| PubMed ID: 23867465	2013
Coordinate activation of Shh and PI3K signaling in PTEN-deficient glioblastoma: new therapeutic opportunities. Nature medicine\| PubMed ID: 24076665	2013
New progenitors NESTIN(g) in the EGL. Nature neuroscience\| PubMed ID: 24270268	2013
Neuronal signaling through endocytosis. Cold Spring Harbor perspectives in biology\| PubMed ID: 24492712	2014
Pediatric low-grade gliomas: how modern biology reshapes the clinical field. Biochimica et biophysica acta\| PubMed ID: 24589977	2014
Shh-proteoglycan interactions regulate maturation of olfactory glomerular circuitry. Developmental neurobiology\| PubMed ID: 24913191	2014
Preserve and protect: maintaining axons within functional circuits. Trends in neurosciences\| PubMed ID: 25167775	2014
The Eya1 phosphatase promotes Shh signaling during hindbrain development and oncogenesis. Developmental cell\| PubMed ID: 25816987	2015
RAS/MAPK Activation Drives Resistance to Smo Inhibition, Metastasis, and Tumor Evolution in Shh Pathway-Dependent Tumors. Cancer research\| PubMed ID: 26130651	2015
How neuronal activity regulates glioma cell proliferation. Neuro-oncology\| PubMed ID: 26359210	2015
A Polyamine Twist on Hedgehog Signaling. Developmental cell\| PubMed ID: 26460938	2015
Prolyl Isomerase Pin1 Regulates Axon Guidance by Stabilizing CRMP2A Selectively in Distal Axons. Cell reports\| PubMed ID: 26489457	2015