Ylva Hellsten

Section of Integrative Physiology, University of Copenhagen

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title Cited by 15	2021

Other Publications

Article	Year
The effect of muscle contraction on the regulation of adenosine formation in rat skeletal muscle cells. The Journal of physiology\| PubMed ID: 10420012	1999
Glycogen-dependent effects of 5-aminoimidazole-4-carboxamide (AICA)-riboside on AMP-activated protein kinase and glycogen synthase activities in rat skeletal muscle. Diabetes\| PubMed ID: 11812734	2002
Regulation of 5'AMP-activated protein kinase activity and substrate utilization in exercising human skeletal muscle. American journal of physiology. Endocrinology and metabolism\| PubMed ID: 12488245	2003
Cytochrome P450 2C9 plays an important role in the regulation of exercise-induced skeletal muscle blood flow and oxygen uptake in humans. The Journal of physiology\| PubMed ID: 12509498	2003
Exercise but not prostanoids enhance levels of vascular endothelial growth factor and other proliferative agents in human skeletal muscle interstitium. The Journal of physiology\| PubMed ID: 12754306	2003
Intense interval training enhances human skeletal muscle oxygen uptake in the initial phase of dynamic exercise at high but not at low intensities. The Journal of physiology\| PubMed ID: 15235098	2004
Effects of alpha-AMPK knockout on exercise-induced gene activation in mouse skeletal muscle. FASEB journal : official publication of the Federation of American Societies for Experimental Biology\| PubMed ID: 15878932	2005
Caffeine-induced Ca(2+) release increases AMPK-dependent glucose uptake in rodent soleus muscle. American journal of physiology. Endocrinology and metabolism\| PubMed ID: 17405829	2007
Calcium signalling in the regulation of PGC-1alpha, PDK4 and HKII mRNA expression. Biological chemistry\| PubMed ID: 17516843	2007
Antioxidant supplementation enhances the exercise-induced increase in mitochondrial uncoupling protein 3 and endothelial nitric oxide synthase mRNA content in human skeletal muscle. Free radical biology & medicine\| PubMed ID: 17602951	2007
Absence of humoral mediated 5'AMP-activated protein kinase activation in human skeletal muscle and adipose tissue during exercise. The Journal of physiology\| PubMed ID: 17962330	2007
PGC-1alpha is not mandatory for exercise- and training-induced adaptive gene responses in mouse skeletal muscle. American journal of physiology. Endocrinology and metabolism\| PubMed ID: 18073319	2008
Passive leg movement enhances interstitial VEGF protein, endothelial cell proliferation, and eNOS mRNA content in human skeletal muscle. American journal of physiology. Regulatory, integrative and comparative physiology\| PubMed ID: 18094062	2008
Reduced volume but increased training intensity elevates muscle Na+-K+ pump alpha1-subunit and NHE1 expression as well as short-term work capacity in humans. American journal of physiology. Regulatory, integrative and comparative physiology\| PubMed ID: 18094063	2008
Four weeks of speed endurance training reduces energy expenditure during exercise and maintains muscle oxidative capacity despite a reduction in training volume. Journal of applied physiology (Bethesda, Md. : 1985)\| PubMed ID: 18845781	2009
Partial neuromuscular blockade in humans enhances muscle blood flow during exercise independently of muscle oxygen uptake and acetylcholine receptor blockade. American journal of physiology. Regulatory, integrative and comparative physiology\| PubMed ID: 19193948	2009
PGC-1alpha mediates exercise-induced skeletal muscle VEGF expression in mice. American journal of physiology. Endocrinology and metabolism\| PubMed ID: 19401459	2009
Attenuated purinergic receptor function in patients with type 2 diabetes. Diabetes\| PubMed ID: 19808895	2010
Exercise training normalizes skeletal muscle vascular endothelial growth factor levels in patients with essential hypertension. Journal of hypertension\| PubMed ID: 20179634	2010
Contraction-induced secretion of VEGF from skeletal muscle cells is mediated by adenosine. American journal of physiology. Heart and circulatory physiology\| PubMed ID: 20543089	2010
Anaerobic energy expenditure and mechanical efficiency during exhaustive leg press exercise. PloS one\| PubMed ID: 20976067	2010
Interstitial and plasma adenosine stimulate nitric oxide and prostacyclin formation in human skeletal muscle. Hypertension (Dallas, Tex. : 1979)\| PubMed ID: 21041702	2010
Exercise training alters the balance between vasoactive compounds in skeletal muscle of individuals with essential hypertension. Hypertension (Dallas, Tex. : 1979)\| PubMed ID: 21896936	2011
Role of nitric oxide and prostanoids in the regulation of leg blood flow and blood pressure in humans with essential hypertension: effect of high-intensity aerobic training. The Journal of physiology\| PubMed ID: 22271868	2012
Skeletal muscle PGC-1α is required for maintaining an acute LPS-induced TNFα response. PloS one\| PubMed ID: 22384185	2012
Opposing effects of nitric oxide and prostaglandin inhibition on muscle mitochondrial Vo(2) during exercise. American journal of physiology. Regulatory, integrative and comparative physiology\| PubMed ID: 22552792	2012
Energy metabolism during repeated sets of leg press exercise leading to failure or not. PloS one\| PubMed ID: 22808209	2012
Lifelong physical activity prevents an age-related reduction in arterial and skeletal muscle nitric oxide bioavailability in humans. The Journal of physiology\| PubMed ID: 22890714	2012
Impaired formation of vasodilators in peripheral tissue in essential hypertension is normalized by exercise training: role of adenosine and prostacyclin. Journal of hypertension\| PubMed ID: 22902871	2012
Subcellular localization and mechanism of secretion of vascular endothelial growth factor in human skeletal muscle. FASEB journal : official publication of the Federation of American Societies for Experimental Biology\| PubMed ID: 23709615	2013
Leg oxygen uptake in the initial phase of intense exercise is slowed by a marked reduction in oxygen delivery. American journal of physiology. Regulatory, integrative and comparative physiology\| PubMed ID: 23720134	2013
Effect of extraluminal ATP application on vascular tone and blood flow in skeletal muscle: implications for exercise hyperemia. American journal of physiology. Regulatory, integrative and comparative physiology\| PubMed ID: 23761642	2013
Effect of nitric oxide synthase inhibition on the exchange of glucose and fatty acids in human skeletal muscle. Nutrition & metabolism\| PubMed ID: 23773265	2013
Effect of lifelong resveratrol supplementation and exercise training on skeletal muscle oxidative capacity in aging mice; impact of PGC-1α. Experimental gerontology\| PubMed ID: 23994519	2013
Exercise-induced capillary growth in human skeletal muscle and the dynamics of VEGF. Microcirculation (New York, N.Y. : 1994)\| PubMed ID: 24450403	2014
Biomarkers of vascular function in premenopausal and recent postmenopausal women of similar age: effect of exercise training. American journal of physiology. Regulatory, integrative and comparative physiology\| PubMed ID: 24477543	2014
Roles of sedentary aging and lifelong physical activity in exchange of glutathione across exercising human skeletal muscle. Free radical biology & medicine\| PubMed ID: 24858720	2014
Exercise training modulates functional sympatholysis and α-adrenergic vasoconstrictor responsiveness in hypertensive and normotensive individuals. The Journal of physiology\| PubMed ID: 24860173	2014
Infusion of ATP increases leg oxygen delivery but not oxygen uptake in the initial phase of intense knee-extensor exercise in humans. Experimental physiology\| PubMed ID: 25085840	2014
Resveratrol modulates the angiogenic response to exercise training in skeletal muscles of aged men. American journal of physiology. Heart and circulatory physiology\| PubMed ID: 25128170	2014
Increased skeletal muscle capillarization enhances insulin sensitivity. American journal of physiology. Endocrinology and metabolism\| PubMed ID: 25352432	2014
Capillary growth in human skeletal muscle: physiological factors and the balance between pro-angiogenic and angiostatic factors. Biochemical Society transactions\| PubMed ID: 25399579	2014
10-20-30 training increases performance and lowers blood pressure and VEGF in runners. Scandinavian journal of medicine & science in sports\| PubMed ID: 25439558	2015
Bengt Saltin (1935-2014). The Journal of physiology\| PubMed ID: 25448186	2014
Effects of Exercise Training on Regulation of Skeletal Muscle Glucose Metabolism in Elderly Men. The journals of gerontology. Series A, Biological sciences and medical sciences\| PubMed ID: 25991826	2015
Reduced blood flow to contracting skeletal muscle in ageing humans: is it all an effect of sand through the hourglass? The Journal of physiology\| PubMed ID: 26095873	2016
What turns off the angiogenic switch in skeletal muscle? Experimental physiology\| PubMed ID: 26130184	2015
Potentiation of cGMP signaling increases oxygen delivery and oxidative metabolism in contracting skeletal muscle of older but not young humans. Physiological reports\| PubMed ID: 26272735	2015
Effect of PDE5 inhibition on the modulation of sympathetic α-adrenergic vasoconstriction in contracting skeletal muscle of young and older recreationally active humans. American journal of physiology. Heart and circulatory physiology\| PubMed ID: 26432842	2015
Advances and challenges in skeletal muscle angiogenesis. American journal of physiology. Heart and circulatory physiology\| PubMed ID: 26608338	2016
Cardiovascular Adaptations to Exercise Training. Comprehensive Physiology\| PubMed ID: 26756625	2015
Vasoactive enzymes and blood flow responses to passive and active exercise in peripheral arterial disease. Atherosclerosis\| PubMed ID: 26771386	2016
Capillary ultrastructure and mitochondrial volume density in skeletal muscle in relation to reduced exercise capacity of patients with intermittent claudication. American journal of physiology. Regulatory, integrative and comparative physiology\| PubMed ID: 27009051	2016
Limitations of skeletal muscle oxygen supply in ageing. The Journal of physiology\| PubMed ID: 27079630	2016
Effects of exercise training and resveratrol on vascular health in aging. Free radical biology & medicine\| PubMed ID: 27085843	2016
Early Postmenopausal Phase Is Associated With Reduced Prostacyclin-Induced Vasodilation That Is Reversed by Exercise Training: The Copenhagen Women Study. Hypertension (Dallas, Tex. : 1979)\| PubMed ID: 27550922	2016
Effect of endurance versus resistance training on quadriceps muscle dysfunction in COPD: a pilot study. International journal of chronic obstructive pulmonary disease\| PubMed ID: 27822028	2016
Adaptations with Intermittent Exercise Training in Post- and Premenopausal Women. Medicine and science in sports and exercise\| PubMed ID: 27992397	2017
Effects of high-intensity training on cardiovascular risk factors in premenopausal and postmenopausal women. American journal of obstetrics and gynecology\| PubMed ID: 28024987	2017
Leg vascular and skeletal muscle mitochondrial adaptations to aerobic high-intensity exercise training are enhanced in the early postmenopausal phase. The Journal of physiology\| PubMed ID: 28231611	2017
The effect of nitric oxide synthase inhibition with and without inhibition of prostaglandins on blood flow in different human skeletal muscles. European journal of applied physiology\| PubMed ID: 28432421	2017
Endothelial mechanotransduction proteins and vascular function are altered by dietary sucrose supplementation in healthy young male subjects. The Journal of physiology\| PubMed ID: 28620941	2017
Cardiac Adaptations to High-Intensity Aerobic Training in Premenopausal and Recent Postmenopausal Women: The Copenhagen Women Study. Journal of the American Heart Association\| PubMed ID: 28862950	2017
Impact of β-adrenergic signaling in PGC-1α-mediated adaptations in mouse skeletal muscle. American journal of physiology. Endocrinology and metabolism\| PubMed ID: 28874356	2018
Effects of menopause and high-intensity training on insulin sensitivity and muscle metabolism. Menopause (New York, N.Y.)\| PubMed ID: 28953212	2018
Exercise training improves blood flow to contracting skeletal muscle of older men via enhanced cGMP signaling. Journal of applied physiology (Bethesda, Md. : 1985)\| PubMed ID: 28982945	2018
Probenecid Inhibits α-Adrenergic Receptor-Mediated Vasoconstriction in the Human Leg Vasculature. Hypertension (Dallas, Tex. : 1979)\| PubMed ID: 29084879	2018
Optimizing hyaluronidase dose and plasmid DNA delivery greatly improves gene electrotransfer efficiency in rat skeletal muscle. Biochemistry and biophysics reports\| PubMed ID: 29124223	2015
Effects of aging and exercise training on leg hemodynamics and oxidative metabolism in the transition from rest to steady-state exercise: role of cGMP signaling. American journal of physiology. Regulatory, integrative and comparative physiology\| PubMed ID: 29668326	2018
Methods for the determination of skeletal muscle blood flow: development, strengths and limitations. European journal of applied physiology\| PubMed ID: 29756164	2018
High-intensity interval, but not endurance, training induces muscle fiber type-specific subsarcolemmal lipid droplet size reduction in type 2 diabetic patients. American journal of physiology. Endocrinology and metabolism\| PubMed ID: 30016151	2018
Leg blood flow and skeletal muscle microvascular perfusion responses to submaximal exercise in peripheral arterial disease. American journal of physiology. Heart and circulatory physiology\| PubMed ID: 30095999	2018
The effect of tyramine infusion and exercise on blood flow, coagulation and clot microstructure in healthy individuals. Thrombosis research\| PubMed ID: 30098458	2018
Effect of menopause and exercise training on plasma apolipoprotein M and sphingosine-1-phosphate. Journal of applied physiology (Bethesda, Md. : 1985)\| PubMed ID: 30433864	2019
The effect of two exercise modalities on skeletal muscle capillary ultrastructure in individuals with type 2 diabetes. Scandinavian journal of medicine & science in sports\| PubMed ID: 30480353	2019
Reduced skeletal-muscle perfusion and impaired ATP release during hypoxia and exercise in individuals with type 2 diabetes. Diabetologia\| PubMed ID: 30607464	2019
The Endothelial Mechanotransduction Protein Platelet Endothelial Cell Adhesion Molecule-1 Is Influenced by Aging and Exercise Training in Human Skeletal Muscle. Frontiers in physiology\| PubMed ID: 30618819	2018
Copenhagen Consensus statement 2019: physical activity and ageing. British journal of sports medicine\| PubMed ID: 30792257	2019
Cardiac perfusion and function after high-intensity exercise training in late premenopausal and recent postmenopausal women: an MRI study. Journal of applied physiology (Bethesda, Md. : 1985)\| PubMed ID: 30870082	2019
Regulatory Mechanisms of Estrogen on Vascular Ageing. Oxidative medicine and cellular longevity\| PubMed ID: 31182992	2019
Muscle-strain injury exudate favors acute tissue healing and prolonged connective tissue formation in humans. FASEB journal : official publication of the Federation of American Societies for Experimental Biology\| PubMed ID: 31211922	2019
On the horizon of aging and physical activity research. Applied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme\| PubMed ID: 31314999	2020
Oestrogen, exercise and vascular function. The Journal of physiology\| PubMed ID: 31571227	2019
Hyperinsulinemia does not cause de novo capillary recruitment in rat skeletal muscle. Microcirculation (New York, N.Y. : 1994)\| PubMed ID: 31605649	2020
Lifelong Physical Activity Determines Vascular Function in Late Postmenopausal Women. Medicine and science in sports and exercise\| PubMed ID: 31609299	2020
Seven-day remote ischaemic preconditioning improves endothelial function in patients with type 2 diabetes mellitus: a randomised pilot study. European journal of endocrinology\| PubMed ID: 31614332	2019
Insulin-induced membrane permeability to glucose in human muscles at rest and following exercise. The Journal of physiology\| PubMed ID: 31696935	2020
Early sarcomere and metabolic defects in a zebrafish cardiac arrhythmia model. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 31704768	2019
Assessment of resistance vessel function in human skeletal muscle: guidelines for experimental design, Doppler ultrasound, and pharmacology. American journal of physiology. Heart and circulatory physiology\| PubMed ID: 31886718	2020
The impact of acute remote ischaemic preconditioning on cerebrovascular function. European journal of applied physiology\| PubMed ID: 31932877	2020
Early time course of change in angiogenic proteins in human skeletal muscle and vascular cells with endurance training. Scandinavian journal of medicine & science in sports\| PubMed ID: 32246511	2020
Effect of aerobic exercise training on asthma in adults: a systematic review and meta-analysis. The European respiratory journal\| PubMed ID: 32350100	2020
Microvascular Function Is Impaired after Short-Term Immobilization in Healthy Men. Medicine and science in sports and exercise\| PubMed ID: 32496738	2020
Inducible deletion of skeletal muscle AMPKα reveals that AMPK is required for nucleotide balance but dispensable for muscle glucose uptake and fat oxidation during exercise. Molecular metabolism\| PubMed ID: 32504885	2020
Ischemic Preconditioning Improves Microvascular Endothelial Function in Remote Vasculature by Enhanced Prostacyclin Production. Journal of the American Heart Association\| PubMed ID: 32750305	2020
Assessment of diabetic foot ulcers based on pictorial material: an interobserver study. Journal of wound care\| PubMed ID: 33175625	2020
Commentaries on Point:Counterpoint: Investigators should/should not control for menstrual cycle phase when performing studies of vascular control. Journal of applied physiology (Bethesda, Md. : 1985)\| PubMed ID: 33197376	2020
Effects of High-Intensity Exercise Training on Adipose Tissue Mass, Glucose Uptake and Protein Content in Pre- and Post-menopausal Women. Frontiers in sports and active living\| PubMed ID: 33345051	2020
Does Exercise Influence the Susceptibility to Arterial Thrombosis? An Integrative Perspective. Frontiers in physiology\| PubMed ID: 33708141	2021
The Impact of Lower Limb Immobilization and Rehabilitation on Angiogenic Proteins and Capillarization in Skeletal Muscle. Medicine and science in sports and exercise\| PubMed ID: 33787530	2021
A High Activity Level Is Required for Augmented Muscle Capillarization in Older Women. Medicine and science in sports and exercise\| PubMed ID: 33844669	2021
Histamine H and H receptors are essential transducers of the integrative exercise training response in humans. Science advances\| PubMed ID: 33853781	2021
Effect of aerobic exercise training on asthma control in postmenopausal women (the ATOM-study): protocol for an outcome assessor, randomised controlled trial. BMJ open\| PubMed ID: 33888532	2021
AXIN1 knockout does not alter AMPK/mTORC1 regulation and glucose metabolism in mouse skeletal muscle. The Journal of physiology\| PubMed ID: 33913171	2021