M. Angela Cenci

Basal Ganglia Pathophysiology Unit, Lund University

Research Area

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title Cited by 9	2020

Other Publications

Article	Year
cAMP response element-binding protein is required for dopamine-dependent gene expression in the intact but not the dopamine-denervated striatum. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 11739600	2001
Pharmacological validation of behavioural measures of akinesia and dyskinesia in a rat model of Parkinson's disease. The European journal of neuroscience\| PubMed ID: 11860512	2002
L-DOPA-induced dyskinesia in the intrastriatal 6-hydroxydopamine model of parkinson's disease: relation to motor and cellular parameters of nigrostriatal function. Neurobiology of disease\| PubMed ID: 12127155	2002
Graft placement and uneven pattern of reinnervation in the striatum is important for development of graft-induced dyskinesia. Neurobiology of disease\| PubMed ID: 16256359	2006
Dyskinesias and dopamine cell replacement in Parkinson's disease: a clinical perspective. Brain research bulletin\| PubMed ID: 16324999	2005
Post- versus presynaptic plasticity in L-DOPA-induced dyskinesia. Journal of neurochemistry\| PubMed ID: 16942598	2006
Endothelial proliferation and increased blood-brain barrier permeability in the basal ganglia in a rat model of 3,4-dihydroxyphenyl-L-alanine-induced dyskinesia. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 16971529	2006
The "motor complication syndrome" in rats with 6-OHDA lesions treated chronically with L-DOPA: relation to dose and route of administration. Behavioural brain research\| PubMed ID: 17157933	2007
Antagonism of metabotropic glutamate receptor type 5 attenuates l-DOPA-induced dyskinesia and its molecular and neurochemical correlates in a rat model of Parkinson's disease. Journal of neurochemistry\| PubMed ID: 17359492	2007
Dopamine dysregulation of movement control in L-DOPA-induced dyskinesia. Trends in neurosciences\| PubMed ID: 17400300	2007
Spatiotemporal pattern of striatal ERK1/2 phosphorylation in a rat model of L-DOPA-induced dyskinesia and the role of dopamine D1 receptors. Biological psychiatry\| PubMed ID: 17662258	2007
L-DOPA-induced dyskinesia: cellular mechanisms and approaches to treatment. Parkinsonism & related disorders\| PubMed ID: 18267248	2007
Ratings of L-DOPA-induced dyskinesia in the unilateral 6-OHDA lesion model of Parkinson's disease in rats and mice. Current protocols in neuroscience\| PubMed ID: 18428668	2007
Pharmacological modulation of glutamate transmission in a rat model of L-DOPA-induced dyskinesia: effects on motor behavior and striatal nuclear signaling. The Journal of pharmacology and experimental therapeutics\| PubMed ID: 19357321	2009
Differential involvement of D1 and D2 dopamine receptors in L-DOPA-induced angiogenic activity in a rat model of Parkinson's disease. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology\| PubMed ID: 19606087	2009
L-DOPA-induced dopamine efflux in the striatum and the substantia nigra in a rat model of Parkinson's disease: temporal and quantitative relationship to the expression of dyskinesia. Journal of neurochemistry\| PubMed ID: 20050978	2010
Plastic effects of L-DOPA treatment in the basal ganglia and their relevance to the development of dyskinesia. Parkinsonism & related disorders\| PubMed ID: 20083009	2009
Rodent models of treatment-induced motor complications in Parkinson's disease. Parkinsonism & related disorders\| PubMed ID: 20123549	2009
A mGluR5 antagonist under clinical development improves L-DOPA-induced dyskinesia in parkinsonian rats and monkeys. Neurobiology of disease\| PubMed ID: 20452425	2010
Maladaptive striatal plasticity in L-DOPA-induced dyskinesia. Progress in brain research\| PubMed ID: 20696322	2010
Maladaptive plasticity of serotonin axon terminals in levodopa-induced dyskinesia. Annals of neurology\| PubMed ID: 20882603	2010
Inhibition of Ras-guanine nucleotide-releasing factor 1 (Ras-GRF1) signaling in the striatum reverts motor symptoms associated with L-dopa-induced dyskinesia. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 21115823	2010
Impact of the lesion procedure on the profiles of motor impairment and molecular responsiveness to L-DOPA in the 6-hydroxydopamine mouse model of Parkinson's disease. Neurobiology of disease\| PubMed ID: 21310234	2011
Vascular endothelial growth factor is upregulated by L-dopa in the parkinsonian brain: implications for the development of dyskinesia. Brain : a journal of neurology\| PubMed ID: 21771855	2011
Current options and future possibilities for the treatment of dyskinesia and motor fluctuations in Parkinson's disease. CNS & neurological disorders drug targets\| PubMed ID: 21838677	2011
Impact of L-DOPA treatment on regional cerebral blood flow and metabolism in the basal ganglia in a rat model of Parkinson's disease. NeuroImage\| PubMed ID: 22406356	2012
Levodopa-induced dyskinesia is strongly associated with resonant cortical oscillations. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 23175810	2012
A model of GDNF gene therapy in mice with 6-Hydroxydopamine lesions: time course of Neurorestorative effects and ERK1/2 activation. Journal of Parkinson's disease\| PubMed ID: 23938263	2012
Bad news for neuroprotective therapies in PD? Journal of Parkinson's disease\| PubMed ID: 24018335	2013
Modulating mGluR5 and 5-HT1A/1B receptors to treat l-DOPA-induced dyskinesia: effects of combined treatment and possible mechanisms of action. Experimental neurology\| PubMed ID: 24029003	2013
Region-specific restoration of striatal synaptic plasticity by dopamine grafts in experimental parkinsonism. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 24170862	2013
Investigating the molecular mechanisms of L-DOPA-induced dyskinesia in the mouse. Parkinsonism & related disorders\| PubMed ID: 24262181	2014
Molecular adaptations of striatal spiny projection neurons during levodopa-induced dyskinesia. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 24599591	2014
Glutamatergic pathways as a target for the treatment of dyskinesias in Parkinson's disease. Biochemical Society transactions\| PubMed ID: 24646284	2014
Mechanisms of dopamine D1 receptor-mediated ERK1/2 activation in the parkinsonian striatum and their modulation by metabotropic glutamate receptor type 5. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 24672017	2014
Pharmacological stimulation of sigma-1 receptors has neurorestorative effects in experimental parkinsonism. Brain : a journal of neurology\| PubMed ID: 24755275	2014
A Genetic Mouse Model of Parkinson's Disease Shows Involuntary Movements and Increased Postsynaptic Sensitivity to Apomorphine. Molecular neurobiology\| PubMed ID: 25307288	2015
Cell type-specific plasticity of striatal projection neurons in parkinsonism and L-DOPA-induced dyskinesia. Nature communications\| PubMed ID: 25360704	2014
Presynaptic Mechanisms of l-DOPA-Induced Dyskinesia: The Findings, the Debate, and the Therapeutic Implications. Frontiers in neurology\| PubMed ID: 25566170	2014
Activity of serotonin 5-HT(1A) receptor 'biased agonists' in rat models of Parkinson's disease and L-DOPA-induced dyskinesia. Neuropharmacology\| PubMed ID: 25645393	2015
Pharmacological stimulation of metabotropic glutamate receptor type 4 in a rat model of Parkinson's disease and L-DOPA-induced dyskinesia: Comparison between a positive allosteric modulator ... Neuropharmacology\| PubMed ID: 25749357	2015
Zooming in on the small: the plasticity of striatal dendritic spines in L-DOPA-induced dyskinesia. Movement disorders : official journal of the Movement Disorder Society\| PubMed ID: 25759263	2015
Rodent models of impulsive-compulsive behaviors in Parkinson's disease: How far have we reached? Neurobiology of disease\| PubMed ID: 26325219	2015
Increased CSF biomarkers of angiogenesis in Parkinson disease. Neurology\| PubMed ID: 26511451	2015
M4 Muscarinic Receptor Signaling Ameliorates Striatal Plasticity Deficits in Models of L-DOPA-Induced Dyskinesia. Neuron\| PubMed ID: 26590347	2015
On the Effect of Eltoprazine in Dyskinetic Hemiparkinsonian Rats. Movement disorders : official journal of the Movement Disorder Society\| PubMed ID: 26749366	2016
Gene therapy blockade of dorsal striatal p11 improves motor function and dyskinesia in parkinsonian mice. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 26787858	2016
Dramatic differences in susceptibility to l-DOPA-induced dyskinesia between mice that are aged before or after a nigrostriatal dopamine lesion. Neurobiology of disease\| PubMed ID: 27312773	2016
Dissociation of metabolic and hemodynamic levodopa responses in the 6-hydroxydopamine rat model. Neurobiology of disease\| PubMed ID: 27544483	2016
Validation of an improved scale for rating l-DOPA-induced dyskinesia in the mouse and effects of specific dopamine receptor antagonists. Neurobiology of disease\| PubMed ID: 27597526	2016
Differential effects of gaseous versus injectable anesthetics on changes in regional cerebral blood flow and metabolism induced by l-DOPA in a rat model of Parkinson's disease. Experimental neurology\| PubMed ID: 28284817	2017
Neuroprotection and neurorestoration as experimental therapeutics for Parkinson's disease. Experimental neurology\| PubMed ID: 28988910	2017
CK2 Oppositely Modulates l-DOPA-Induced Dyskinesia via Striatal Projection Neurons Expressing D1 or D2 Receptors. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 29097596	2017
Translating scientific advances into disease-modifying therapies for Parkinson's Disease. Experimental neurology\| PubMed ID: 29145992	2017
Levodopa-induced abnormal involuntary movements correlate with altered permeability of the blood-brain-barrier in the basal ganglia. Scientific reports\| PubMed ID: 29167476	2017
Animal models of l-dopa-induced dyskinesia in Parkinson's disease. Movement disorders : official journal of the Movement Disorder Society\| PubMed ID: 29488257	2018
mGlu receptors in the treatment of Parkinson's disease and L-DOPA-induced dyskinesia. Current opinion in pharmacology\| PubMed ID: 29625424	2018
On the neuronal circuitry mediating L-DOPA-induced dyskinesia. Journal of neural transmission (Vienna, Austria : 1996)\| PubMed ID: 29704061	2018
Striatonigral neurons divide into two distinct morphological-physiological phenotypes after chronic L-DOPA treatment in parkinsonian rats. Scientific reports\| PubMed ID: 29968767	2018
Significance and Translational Value of High-Frequency Cortico-Basal Ganglia Oscillations in Parkinson's Disease. Journal of Parkinson's disease\| PubMed ID: 30594935	2019
Pridopidine Induces Functional Neurorestoration Via the Sigma-1 Receptor in a Mouse Model of Parkinson's Disease. Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics\| PubMed ID: 30756361	2019
Seeding of protein aggregation causes cognitive impairment in rat model of cortical synucleinopathy. Movement disorders : official journal of the Movement Disorder Society\| PubMed ID: 31449702	2019
Dyskinesia matters. Movement disorders : official journal of the Movement Disorder Society\| PubMed ID: 31872501	2020
D1-mGlu5 heteromers mediate noncanonical dopamine signaling in Parkinson's disease. The Journal of clinical investigation\| PubMed ID: 32039920	2020
The role of glia in Parkinson's disease: Emerging concepts and therapeutic applications. Progress in brain research\| PubMed ID: 32247363	2020
Animal models for preclinical Parkinson's research: An update and critical appraisal. Progress in brain research\| PubMed ID: 32247366	2020
Preface: The evolving scenario of Parkinson's research. Progress in brain research\| PubMed ID: 32247377	2020
Reply to: Letter to Editor by Chaudhuri, Jenner, Antonini. Movement disorders : official journal of the Movement Disorder Society\| PubMed ID: 32415716	2020