Xi Lei

Department of Pharmacology, University of Saskatchewan

Affiliated withUniversity of Saskatchewan

Research Area

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title Cited by 21	2011

Other Publications

Article	Year
Evidence that NOS2 acts as a trigger and mediator of late preconditioning induced by acute systemic hypoxia. American journal of physiology. Heart and circulatory physiology\| PubMed ID: 12063268	2002
Exercise does not protect the female heart: an unconvincing conclusion? Circulation research\| PubMed ID: 12169655	2002
Sildenafil induces delayed preconditioning through inducible nitric oxide synthase-dependent pathway in mouse heart. Circulation research\| PubMed ID: 12637371	2003
Sildenafil-induced cardioprotection in rabbits. Cardiovascular research\| PubMed ID: 14659816	2003
Cardioprotection with phosphodiesterase-5 inhibition--a novel preconditioning strategy. Journal of molecular and cellular cardiology\| PubMed ID: 14871543	2004
Opening of Ca2+-activated K+ channels triggers early and delayed preconditioning against I/R injury independent of NOS in mice. American journal of physiology. Heart and circulatory physiology\| PubMed ID: 15217801	2004
Cobalt chloride induces delayed cardiac preconditioning in mice through selective activation of HIF-1alpha and AP-1 and iNOS signaling. American journal of physiology. Heart and circulatory physiology\| PubMed ID: 15284066	2004
Phosphodiesterase-5 inhibitor sildenafil preconditions adult cardiac myocytes against necrosis and apoptosis. Essential role of nitric oxide signaling. The Journal of biological chemistry\| PubMed ID: 15668244	2005
Pharmacological preconditioning with sildenafil: Basic mechanisms and clinical implications. Vascular pharmacology\| PubMed ID: 15922255	2005
Silencing heat shock factor 1 by small interfering RNA abrogates heat shock-induced cardioprotection against ischemia-reperfusion injury in mice. Journal of molecular and cellular cardiology\| PubMed ID: 16125197	2005
Genetic deletion of fas receptors or Fas ligands does not reduce infarct size after acute global ischemia-reperfusion in isolated mouse heart. Cell biochemistry and biophysics\| PubMed ID: 16456239	2006
Hypercholesterolemia enhances tolerance to lethal systemic hypoxia in middle-aged mice: possible role of VEGF downregulation in brain. Molecular and cellular biochemistry\| PubMed ID: 16718361	2006
[Dynamic changes of morphological parameters of tobacco root in field]. Ying yong sheng tai xue bao = The journal of applied ecology / Zhongguo sheng tai xue xue hui, Zhongguo ke xue yuan Shenyang ying yong sheng tai yan jiu suo zhu ban\| PubMed ID: 16724726	2006
Rapamycin confers preconditioning-like protection against ischemia-reperfusion injury in isolated mouse heart and cardiomyocytes. Journal of molecular and cellular cardiology\| PubMed ID: 16769083	2006
eNOS phosphorylation: a pivotal molecular switch in vasodilation and cardioprotection? Journal of molecular and cellular cardiology\| PubMed ID: 17174975	2007
Effects of salicylic acid on post-ischaemic ventricular function and purine efflux in isolated mouse hearts. Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals\| PubMed ID: 17852081	2007
Essential role of mitochondrial Ca2+-activated and ATP-sensitive K+ channels in sildenafil-induced late cardioprotection. Journal of molecular and cellular cardiology\| PubMed ID: 18021798	2008
Protein kinase G-dependent cardioprotective mechanism of phosphodiesterase-5 inhibition involves phosphorylation of ERK and GSK3beta. The Journal of biological chemistry\| PubMed ID: 18723505	2008
The current strategy of repair of tetralogy of Fallot in children and adults. Cardiology in the young\| PubMed ID: 18812012	2008
Loss of myocardial ischemic postconditioning in adenosine A1 and bradykinin B2 receptors gene knockout mice. Circulation\| PubMed ID: 18824766	2008
Commentaries on viewpoint: effect of altitude on leptin, does it go up or down? Journal of applied physiology (Bethesda, Md. : 1985)\| PubMed ID: 19031619	2008
Pivotal effects of phosphodiesterase inhibitors on myocyte contractility and viability in normal and ischemic hearts. Acta pharmacologica Sinica\| PubMed ID: 19060915	2009
ERK phosphorylation mediates sildenafil-induced myocardial protection against ischemia-reperfusion injury in mice. American journal of physiology. Heart and circulatory physiology\| PubMed ID: 19286961	2009
Investigation of voltammetric enzyme-linked immunoassay system based on N-heterocyclic substrate of 2,3-diaminopyridine. Talanta\| PubMed ID: 19362207	2009
The protective effects of ambroxol on radiation lung injury and influence on production of transforming growth factor beta1 and tumor necrosis factor alpha. Medical oncology (Northwood, London, England)\| PubMed ID: 19636975	2010
Investigation on solvation and protonation of meso-tetrakis(p-sulfonatophenyl)porphyrin in imidazolium-based ionic liquids by spectroscopic methods. Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy\| PubMed ID: 19648056	2009
Design of one-to-one recognition triple Au nanoparticles DNA probe and its application in the electrochemical DNA biosensor. Chemical communications (Cambridge, England)\| PubMed ID: 19904360	2009
A rapid and simple chemiluminescence method for screening levels of inosine and hypoxanthine in non-traumatic chest pain patients. Luminescence : the journal of biological and chemical luminescence\| PubMed ID: 20017127	2011
Long-acting phosphodiesterase-5 inhibitor tadalafil attenuates doxorubicin-induced cardiomyopathy without interfering with chemotherapeutic effect. The Journal of pharmacology and experimental therapeutics\| PubMed ID: 20543097	2010
Hypoxia inducible factor 1 (HIF-1) and cardioprotection. Acta pharmacologica Sinica\| PubMed ID: 20711226	2010
Identification of protein targets underlying dietary nitrate-induced protection against doxorubicin cardiotoxicity. Journal of cellular and molecular medicine\| PubMed ID: 21251210	2011
Photoacoustic imaging based on MEMS mirror scanning. Biomedical optics express\| PubMed ID: 21258548	2010
Early changes in morphology and intraocular pressure by size of clear corneal incision. Cornea\| PubMed ID: 21282997	2011
Dietary nitrate supplementation protects against Doxorubicin-induced cardiomyopathy by improving mitochondrial function. Journal of the American College of Cardiology\| PubMed ID: 21596234	2011
CXCL12 G801A polymorphism and breast cancer risk: a meta-analysis. Molecular biology reports\| PubMed ID: 21643956	2012
Type 2 diabetic Obese db/db mice are refractory to myocardial ischemic postconditioning In Vivo: potential role for Hsp20, F(1) -ATPase Î´, and Echs1. Journal of cellular and molecular medicine\| PubMed ID: 21722304	2011
Integrated diffuse optical tomography and photoacoustic tomography: phantom validations. Biomedical optics express\| PubMed ID: 21833371	2011
Dysregulated atrial gene expression of osteoprotegerin/receptor activator of nuclear factor-ÎºB (RANK)/RANK ligand axis in the development and progression of atrial fibrillation. Circulation journal : official journal of the Japanese Circulation Society\| PubMed ID: 22001292	2011
Emerging new uses of phosphodiesterase-5 inhibitors in cardiovascular diseases. Experimental and clinical cardiology\| PubMed ID: 22131856	2011
Quantitative assessment of the effect of MTHFR polymorphisms on the risk of lung carcinoma. Molecular biology reports\| PubMed ID: 22215214	2012
Chronic treatment with long acting phosphodiesterase-5 inhibitor tadalafil alters proteomic changes associated with cytoskeletal rearrangement and redox regulation in Type 2 diabetic hearts. Basic research in cardiology\| PubMed ID: 22311732	2012