Liying Yan

Center for Reproductive Medicine, Peking University Third Hospital

Affiliated withPeking University Third Hospital National Clinical Research Center for Obstetrics and Gynecology Key Laboratory of Assisted Reproduction, Ministry of Education

Research Area

Medicine

Biography

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title Cited by 6	2021

Other Publications

Article	Year
Poor intracytoplasmic sperm injection outcome in infertile males with azoospermia factor c microdeletions. Fertility and sterility\| PubMed ID: 33745721	2021
Association of TRB3 Q84R polymorphism with polycystic ovary syndrome in Chinese women. Reproductive biology and endocrinology : RB&E\| PubMed ID: 21492415	2011
In vitro maturation of cumulus-partially enclosed immature human oocytes by priming with gonadotropin. Fertility and sterility\| PubMed ID: 21762899	2011
Effects of combined epidermal growth factor, brain-derived neurotrophic factor and insulin-like growth factor-1 on human oocyte maturation and early fertilized and cloned embryo development. Human reproduction (Oxford, England)\| PubMed ID: 22532606	2012
Successful reprogramming of differentiated cells by somatic cell nuclear transfer, using in vitro-matured oocytes with a modified activation method. Journal of tissue engineering and regenerative medicine\| PubMed ID: 22589148	2013
Prenatal diagnosis and postnatal followup of partial trisomy 13q and partial monosomy 10p: a case report and review of the literature. Case reports in genetics\| PubMed ID: 23133763	2012
Excessive intrauterine fluid cause aberrant implantation and pregnancy outcome in mice. PloS one\| PubMed ID: 24194934	2013
Whole-genome analysis of 5-hydroxymethylcytosine and 5-methylcytosine at base resolution in the human brain. Genome biology\| PubMed ID: 24594098	2014
Advances in preimplantation genetic diagnosis/screening. Science China. Life sciences\| PubMed ID: 24907939	2014
The DNA methylation landscape of human early embryos. Nature\| PubMed ID: 25079557	2014
Validation of multiple annealing and looping-based amplification cycle sequencing for 24-chromosome aneuploidy screening of cleavage-stage embryos. Fertility and sterility\| PubMed ID: 25241375	2014
Mesenchymal Stem Cells Enhance Angiogenesis and Follicle Survival in Human Cryopreserved Ovarian Cortex Transplantation. Cell transplantation\| PubMed ID: 25353724	2015
Effect of vitrification at the germinal vesicle stage on the global methylation status in mouse oocytes subsequently matured in vitro. Chinese medical journal\| PubMed ID: 25430442	2014
Identification of a human subcortical maternal complex. Molecular human reproduction\| PubMed ID: 25542835	2015
Mesenchymal Stem Cells Facilitate In Vitro Development of Human Preantral Follicle. Reproductive sciences (Thousand Oaks, Calif.)\| PubMed ID: 25854744	2015
High-fat diets exaggerate endocrine and metabolic phenotypes in a rat model of DHEA-induced PCOS. Reproduction (Cambridge, England)\| PubMed ID: 26814210	2016
Human single follicle growth in vitro from cryopreserved ovarian tissue after slow freezing or vitrification. Human reproduction (Oxford, England)\| PubMed ID: 26851603	2016
Validation of a next-generation sequencing-based protocol for 24-chromosome aneuploidy screening of blastocysts. Fertility and sterility\| PubMed ID: 26902859	2016
Fractalkine restores the decreased expression of StAR and progesterone in granulosa cells from patients with polycystic ovary syndrome. Scientific reports\| PubMed ID: 27386819	2016
Clinical applications of MARSALA for preimplantation genetic diagnosis of spinal muscular atrophy. Journal of genetics and genomics = Yi chuan xue bao\| PubMed ID: 27599922	2016
Re-analysis of aneuploidy blastocysts with an inner cell mass and different regional trophectoderm cells. Journal of assisted reproduction and genetics\| PubMed ID: 28188593	2017
Testosterone Represses Estrogen Signaling by Upregulating miR-22: A Mechanism for Imbalanced Steroid Hormone Production in Preeclampsia. Hypertension (Dallas, Tex. : 1979)\| PubMed ID: 28193709	2017
Mesenchymal stem cell-derived angiogenin promotes primodial follicle survival and angiogenesis in transplanted human ovarian tissue. Reproductive biology and endocrinology : RB&E\| PubMed ID: 28274269	2017
[Advance in the methods of preimplantation genetic diagnosis for single gene diseases]. Zhonghua yi xue yi chuan xue za zhi = Zhonghua yixue yichuanxue zazhi = Chinese journal of medical genetics\| PubMed ID: 28604975	2017
Single-cell DNA methylome sequencing of human preimplantation embryos. Nature genetics\| PubMed ID: 29255258	2018
Activation of hedgehog signaling and its association with cisplatin resistance in ovarian epithelial tumors. Oncology letters\| PubMed ID: 29552194	2018
Tracing the temporal-spatial transcriptome landscapes of the human fetal digestive tract using single-cell RNA-sequencing. Nature cell biology\| PubMed ID: 29802404	2018
Transcriptome analysis of PCOS arrested 2-cell embryos. Cell cycle (Georgetown, Tex.)\| PubMed ID: 29912628	2018
Publisher Correction: Tracing the temporal-spatial transcriptome landscapes of the human fetal digestive tract using single-cell RNA-sequencing. Nature cell biology\| PubMed ID: 30038257	2018
Endometrial miR-543 Is Downregulated During the Implantation Window in Women With Endometriosis-Related Infertility. Reproductive sciences (Thousand Oaks, Calif.)\| PubMed ID: 30231774	2019
Identifying normal embryos from reciprocal translocation carriers by whole chromosome haplotyping. Journal of genetics and genomics = Yi chuan xue bao\| PubMed ID: 30287172	2018
The present and future of whole-exome sequencing in studying and treating human reproductive disorders. Journal of genetics and genomics = Yi chuan xue bao\| PubMed ID: 30391409	2018
Transcriptome Landscape of Human Folliculogenesis Reveals Oocyte and Granulosa Cell Interactions. Molecular cell\| PubMed ID: 30472193	2018
Single-cell multiomics sequencing and analyses of human colorectal cancer. Science (New York, N.Y.)\| PubMed ID: 30498128	2018
Risk of miscarriage in women with endometriosis undergoing IVF fresh cycles: a retrospective cohort study. Reproductive biology and endocrinology : RB&E\| PubMed ID: 30755216	2019
Epigenetic Regulation and Risk Factors During the Development of Human Gametes and Early Embryos. Annual review of genomics and human genetics\| PubMed ID: 30917080	2019
Genetic testing and PGD for unexplained recurrent fetal malformations with MAGEL2 gene mutation. Science China. Life sciences\| PubMed ID: 31152388	2019
Genetic analysis and preimplantation genetic diagnosis of Chinese Marfan syndrome patients. Journal of genetics and genomics = Yi chuan xue bao\| PubMed ID: 31279624	2019
Trio-whole-exome sequencing and preimplantation genetic diagnosis for unexplained recurrent fetal malformations. Human mutation\| PubMed ID: 31680349	2020
scHaplotyper: haplotype construction and visualization for genetic diagnosis using single cell DNA sequencing data. BMC bioinformatics\| PubMed ID: 32007105	2020
A novel homozygous mutation of phospholipase C zeta leading to defective human oocyte activation and fertilization failure. Human reproduction (Oxford, England)\| PubMed ID: 32142120	2020
Bioinspired l-Proline Oligomers for the Cryopreservation of Oocytes Controlling Ice Growth. ACS applied materials & interfaces\| PubMed ID: 32227894	2020
Novel PGD strategy based on single sperm linkage analysis for carriers of single gene pathogenic variant and chromosome reciprocal translocation. Journal of assisted reproduction and genetics\| PubMed ID: 32350783	2020
Single-cell transcriptome analysis of the novel coronavirus (SARS-CoV-2) associated gene ACE2 expression in normal and non-obstructive azoospermia (NOA) human male testes. Science China. Life sciences\| PubMed ID: 32361911	2020
A strategy using SNP linkage analysis for monogenic diseases PGD combined with HLA typing. Clinical genetics\| PubMed ID: 32378203	2020
Effect of serum 25-hydroxyvitamin D levels on sperm quality and assisted reproductive technology outcomes for men of infertile Chinese couples. Andrology\| PubMed ID: 32412142	2020
Effects of oocyte vitrification on the behaviors and physiological indexes of aged first filial generation mice. Cryobiology\| PubMed ID: 32598946	2020
A novel pathogenic mutation in FBN2 associated with congenital contractural arachnodactyly for preimplantation genetic diagnosis. Journal of genetics and genomics = Yi chuan xue bao\| PubMed ID: 32747207	2020
SARS-CoV-2 Entry Factors: and Are Expressed in Peri-Implantation Embryos and the Maternal-Fetal Interface. Engineering (Beijing, China)\| PubMed ID: 32837754	2020
Effects of vitrification and cryostorage duration on single-cell RNA-Seq profiling of vitrified-thawed human metaphase II oocytes. Frontiers of medicine\| PubMed ID: 32876878	2021
Dissecting the epigenomic dynamics of human fetal germ cell development at single-cell resolution. Cell research\| PubMed ID: 32884136	2021
Integrated multi-omics reveal epigenomic disturbance of assisted reproductive technologies in human offspring. EBioMedicine\| PubMed ID: 33099088	2020
The methylome of a human polar body reflects that of its sibling oocyte and its aberrance may indicate poor embryo development. Human reproduction (Oxford, England)\| PubMed ID: 33313772	2021
Epigenetic consequences of hormonal interactions between opposite-sex twin fetuses. Clinical and translational medicine\| PubMed ID: 33377650	2020
Single-cell multiomics sequencing reveals the functional regulatory landscape of early embryos. Nature communications\| PubMed ID: 33623021	2021
Clinical application of an NGS-based method in the preimplantation genetic testing for Duchenne muscular dystrophy. Journal of assisted reproduction and genetics\| PubMed ID: 33719023	2021
Age-related changes in human conventional semen parameters and sperm chromatin structure assay-defined sperm DNA/chromatin integrity. Reproductive biomedicine online\| PubMed ID: 33785305	2021
A comprehensive PGT-M strategy for ADPKD patients with de novo PKD1 mutations using affected embryo or gametes as proband. Journal of assisted reproduction and genetics\| PubMed ID: 33939064	2021