Flora Meilleur

Department of Molecular and Structural Biochemistry, North Carolina State University

Affiliated withNorth Carolina State University Oak Ridge National Laboratory

Research Area

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JoVE Journal Publications

ArticleTotal : 2	Year
Publication title Cited by 8	2020
Publication title	2023

Other Publications

Article	Year
Expression, purification, assay, and crystal structure of perdeuterated human arginase I. Archives of biochemistry and biophysics\| PubMed ID: 17562323	2007
Deuterium labeling for neutron structure-function-dynamics analysis. Methods in molecular biology (Clifton, N.J.)\| PubMed ID: 19488706	2009
The structure of Sindbis virus produced from vertebrate and invertebrate hosts as determined by small-angle neutron scattering. Journal of virology\| PubMed ID: 20219936	2010
Crystallization and preliminary X-ray diffraction analysis of red clover necrotic mosaic virus. Acta crystallographica. Section F, Structural biology and crystallization communications\| PubMed ID: 21045294	2010
Conformational changes in Sindbis virus induced by decreased pH are revealed by small-angle neutron scattering. Journal of virology\| PubMed ID: 22156534	2012
Open conformation of ezrin bound to phosphatidylinositol 4,5-bisphosphate and to F-actin revealed by neutron scattering. The Journal of biological chemistry\| PubMed ID: 22927432	2012
New insight into the structure of RNA in red clover necrotic mosaic virus and the role of divalent cations revealed by small-angle neutron scattering. Archives of virology\| PubMed ID: 23483344	2013
Refinement of macromolecular structures against neutron data with Journal of applied crystallography\| PubMed ID: 24587788	2014
Crystallization and preliminary X-ray diffraction analysis of Hypocrea jecorina Cel7A in two new crystal forms. Acta crystallographica. Section F, Structural biology communications\| PubMed ID: 24915091	2014
Production and characterization of recombinant perdeuterated cholesterol oxidase. Analytical biochemistry\| PubMed ID: 26073659	2015
Neutron Crystal Structure of RAS GTPase Puts in Question the Protonation State of the GTP γ-Phosphate. The Journal of biological chemistry\| PubMed ID: 26515069	2015
Neutron protein crystallography: A complementary tool for locating hydrogens in proteins. Archives of biochemistry and biophysics\| PubMed ID: 26592456	2016
Crystal structures of wild-type Trichoderma reesei Cel7A catalytic domain in open and closed states. FEBS letters\| PubMed ID: 27943301	2016
Oxygen Activation at the Active Site of a Fungal Lytic Polysaccharide Monooxygenase. Angewandte Chemie (International ed. in English)\| PubMed ID: 28004877	2017
An extended N-H bond, driven by a conserved second-order interaction, orients the flavin N5 orbital in cholesterol oxidase. Scientific reports\| PubMed ID: 28098177	2017
Crystallization of a fungal lytic polysaccharide monooxygenase expressed from glycoengineered Pichia pastoris for X-ray and neutron diffraction. Acta crystallographica. Section F, Structural biology communications\| PubMed ID: 28177316	2017
Structural studies of Neurospora crassa LPMO9D and redox partner CDHIIA using neutron crystallography and small-angle scattering. Carbohydrate research\| PubMed ID: 28291519	2017
Neutron structure of the T26H mutant of T4 phage lysozyme provides insight into the catalytic activity of the mutant enzyme and how it differs from that of wild type. Protein science : a publication of the Protein Society\| PubMed ID: 28707339	2017
Neutron crystallographic studies of T4 lysozyme at cryogenic temperature. Protein science : a publication of the Protein Society\| PubMed ID: 28707382	2017
Structural investigation of cellobiose dehydrogenase IIA: Insights from small angle scattering into intra- and intermolecular electron transfer mechanisms. Biochimica et biophysica acta. General subjects\| PubMed ID: 29374564	2018
Modulating Enzyme Activity by Altering Protein Dynamics with Solvent. Biochemistry\| PubMed ID: 29901984	2018
IMAGINE: neutrons reveal enzyme chemistry. Acta crystallographica. Section D, Structural biology\| PubMed ID: 30082513	2018
Titration of ionizable groups in proteins using multiple neutron data sets from a single crystal: application to the small GTPase Ras. Acta crystallographica. Section F, Structural biology communications\| PubMed ID: 30713162	2019
Neutron and X-ray analysis of the Fenna-Matthews-Olson photosynthetic antenna complex from Prosthecochloris aestuarii. Acta crystallographica. Section F, Structural biology communications\| PubMed ID: 30839291	2019
Dynamic nuclear polarization enhanced neutron crystallography: Amplifying hydrogen in biological crystals. Methods in enzymology\| PubMed ID: 32093831	2020
IMAGINE: The neutron protein crystallography beamline at the high flux isotope reactor. Methods in enzymology\| PubMed ID: 32093843	2020
Preliminary results of neutron and X-ray diffraction data collection on a lytic polysaccharide monooxygenase under reduced and acidic conditions. Acta crystallographica. Section F, Structural biology communications\| PubMed ID: 33830078	2021
Metalloprotein catalysis: structural and mechanistic insights into oxidoreductases from neutron protein crystallography. Acta crystallographica. Section D, Structural biology\| PubMed ID: 34605429	2021
The mechanisms of catalysis and ligand binding for the SARS-CoV-2 NSP3 macrodomain from neutron and X-ray diffraction at room temperature. bioRxiv : the preprint server for biology\| PubMed ID: 35169801	2022
The P132H mutation in the main protease of Omicron SARS-CoV-2 decreases thermal stability without compromising catalysis or small-molecule drug inhibition. Cell research\| PubMed ID: 35292745	2022
The mechanisms of catalysis and ligand binding for the SARS-CoV-2 NSP3 macrodomain from neutron and x-ray diffraction at room temperature. Science advances\| PubMed ID: 35622909	2022
Changes in active-site geometry on X-ray photoreduction of a lytic polysaccharide monooxygenase active-site copper and saccharide binding. IUCrJ\| PubMed ID: 36071795	2022
Complementarity of neutron, XFEL and synchrotron crystallography for defining the structures of metalloenzymes at room temperature. IUCrJ\| PubMed ID: 36071813	2022
Mapping H in the Nanoscale (AC)-Ag Fluorophore. The journal of physical chemistry letters\| PubMed ID: 36453924	2022
Capture of activated dioxygen intermediates at the copper-active site of a lytic polysaccharide monooxygenase. Chemical science\| PubMed ID: 36507176	2022
Joint X-ray/neutron structure of Lentinus similis AA9_A at room temperature. Acta crystallographica. Section F, Structural biology communications\| PubMed ID: 36598350	2023