use-percutaneous-ventricular-assist-deviceleft-atrium-to-femoral

Use of a Percutaneous Ventricular Assist Device/Left Atrium to Femoral Artery Bypass System for Cardiogenic Shock

The left atrial to femoral artery bypass (LAFAB) system is a mechanical circulatory support (MCS) device used in cardiogenic shock (CS) that bypasses the ...

Virginia Heart/Inova Heart and Vascular Institute

War on Shock.

After Action Reviews.

Leveraging the Power of Marginal Gains to Improve Outcomes in Interventional Cardiology.

The Art of the Possible.

SCAI position statement on optimal percutaneous coronary interventional therapy for complex coronary artery disease.

Known Knowns, Known Unknowns, and Unknown Unknowns.

Cardiac safety research consortium "shock II" think tank report: Advancing practical approaches to generating evidence for the treatment of cardiogenic shock.

Association, causation, and correlation.

Percutaneous ventricular assist devices (pVAD) are frequently utilized in high-risk percutaneous coronary intervention (HR-PCI) to provide hemodynamic support in patients with complex cardiovascular disease and/or multiple comorbidities who are poor candidates for surgical revascularization. Using the National Inpatient Sample we identified pVAD-assisted PCI (excluding intra-aortic balloon pump) in patients without cardiogenic shock from January 2008 to December 2018. We evaluated the trends in patient and procedural characteristics, and complication rates across the 11-year study period. A total of 26,661 pVAD-PCI was performed. From 2008 to 2018 there has was a 27-fold increase in the number of pVAD-PCIs performed annually. There has also been an increase in the proportion of procedures performed in small to medium sized hospitals. The use of atherectomy, image-guided PCI, FFR/iFR, drug-eluting stents, and multi-vessel intervention has significantly increased. Patients undergoing pVAD-PCI had a higher burden of comorbidities, without a significant difference in mortality over time. There were decreased rates of acute stroke and blood transfusions over time, while vascular complications and acute kidney injury (AKI) requiring dialysis remained mostly unchanged. In conclusion, the use of pVAD for HR-PCI has increased significantly, along with adjunctive PCI techniques such as atherectomy, intravascular imaging, and physiologic lesion assessment. With increasing use of this device, there appeared to be lower rates of peri-procedural stroke, and blood transfusions. Despite a higher burden of comorbidities, adjusted mortality remained stable over time.

Trends in the Outcomes of High-risk Percutaneous Ventricular Assist Device-assisted Percutaneous Coronary Intervention, 2008-2018.

Article	Year
War on Shock. The Journal of invasive cardiology\| PubMed ID: 28045675	2017
After Action Reviews. The Journal of invasive cardiology\| PubMed ID: 31671068	2019
Leveraging the Power of Marginal Gains to Improve Outcomes in Interventional Cardiology. JAMA cardiology\| PubMed ID: 31693061	2020
The Art of the Possible. Cardiovascular revascularization medicine : including molecular interventions\| PubMed ID: 31952918	2020
SCAI position statement on optimal percutaneous coronary interventional therapy for complex coronary artery disease. Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions\| PubMed ID: 32406991	2020
Known Knowns, Known Unknowns, and Unknown Unknowns. Cardiovascular revascularization medicine : including molecular interventions\| PubMed ID: 32988744	2020
Cardiac safety research consortium "shock II" think tank report: Advancing practical approaches to generating evidence for the treatment of cardiogenic shock. American heart journal\| PubMed ID: 33011148	2020
Association, causation, and correlation. Cardiovascular revascularization medicine : including molecular interventions\| PubMed ID: 34303623	2021
Trends in the Outcomes of High-risk Percutaneous Ventricular Assist Device-assisted Percutaneous Coronary Intervention, 2008-2018. The American journal of cardiology\| PubMed ID: 34344515	2021

Alexander Truesdell

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