Irfan Saadi

Irfan Saadi

Department of Anatomy and Cell Biology, University of Kansas Medical Center

Affiliated withUniversity of Kansas Medical Center

Research Area

Biography

Dr. Irfan Saadi has always been interested in understanding the etiology of congenital malformations. He received his B.Sc. (Hon.) and M.Sc. degrees in Biology from McGill University in Montreal, Canada, where he began his research career in Dr. Rima Rozen’s laboratory working on genotype-phenotype correlation in patients with congenital renal disease. He then earned his Ph.D. in Genetics from the University of Iowa in Dr. Andrew Russo’s laboratory studying the molecular consequences of disease-causing mutations in Axenfeld-Rieger syndrome, which primarily affects craniofacial and ocular development. His postdoctoral training at Harvard was in developmental genetic analyses of palate and tooth development with Dr. Richard Maas, a preeminent scholar of craniofacial morphogenesis. Dr. Saadi joined the Department of Anatomy and Cell Biology at the University of Kansas Medical Center in 2011 as an Assistant Professor. He is currently an Associate Professor with Tenure. His research is focused on understanding the molecular mechanisms underlying the dynamics of embryonic morphogenesis and how changes in these dynamics can lead to congenital anomalies of the craniofacial region.

JoVE Journal Publications

ArticleTotal : 1
Year
Isolation and Time-Lapse Imaging of Primary Mouse Embryonic Palatal Mesenchyme Cells to Analyze Collective Movement Attributes
Publication title

Cited by 3

2021

Other Publications

Article
Year
Msx1 and Tbx2 antagonistically regulate Bmp4 expression during the bud-to-cap stage transition in tooth development.

Development (Cambridge, England)| PubMed ID: 23720046

2013
2013
Confirmation and further delineation of the 3q26.33-3q27.2 microdeletion syndrome.

European journal of medical genetics| PubMed ID: 24462885

2014
2015
THPO-MPL pathway and bone marrow failure.

Hematology/oncology and stem cell therapy| PubMed ID: 25482588

2015
2016
2018
2019
2019
2020
SPECC1L regulates palate development downstream of IRF6.

Human molecular genetics| PubMed ID: 31943082

2020
2021