Diogo O. Souza

Graduate Program in Biochemistry, Universidade Federal do Rio Grande do Sul

Affiliated withUniversidade Federal do Rio Grande do Sul

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title	2021

Other Publications

Article	Year
Serum S100B levels in patients with lupus erythematosus: preliminary observation. Clinical and diagnostic laboratory immunology\| PubMed ID: 11777848	2002
Quinolinic acid stimulates synaptosomal glutamate release and inhibits glutamate uptake into astrocytes. Neurochemistry international\| PubMed ID: 11900857	2002
Utilization of energy nutrients by cerebellar slices. Neurochemical research\| PubMed ID: 11958517	2002
Intrahippocampal infusion of ebselen impairs retention of an inhibitory avoidance task in rats. European journal of pharmacology\| PubMed ID: 12231387	2002
The adenosine antagonist theophylline impairs p50 auditory sensory gating in normal subjects. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology\| PubMed ID: 12377399	2002
Effect of undernutrition on GMP-PNP binding and adenylate cyclase activity from rat brain. Cellular and molecular neurobiology\| PubMed ID: 12469877	2002
Methylmercury inhibits glutamate uptake by synaptic vesicles from rat brain. Neuroreport\| PubMed ID: 12657889	2003
Effects of undernutrition on glutamatergic parameters in rat brain. Neurochemical research\| PubMed ID: 12834257	2003
Neuroprotective effect of ebselen on rat hippocampal slices submitted to oxygen-glucose deprivation: correlation with immunocontent of inducible nitric oxide synthase. Neuroscience letters\| PubMed ID: 12850558	2003
Ebselen protects against methylmercury-induced inhibition of glutamate uptake by cortical slices from adult mice. Toxicology letters\| PubMed ID: 12927352	2003
Diphenyl diselenide protects rat hippocampal slices submitted to oxygen-glucose deprivation and diminishes inducible nitric oxide synthase immunocontent. Brain research\| PubMed ID: 12965245	2003
Effects of L-2-hydroxyglutaric acid on various parameters of the glutamatergic system in cerebral cortex of rats. Metabolic brain disease\| PubMed ID: 14567473	2003
In vitro effects of D-2-hydroxyglutaric acid on glutamate binding, uptake and release in cerebral cortex of rats. Journal of the neurological sciences\| PubMed ID: 14706223	2004
Increase in serum S100B protein level after a swimming race. Canadian journal of applied physiology = Revue canadienne de physiologie appliquee\| PubMed ID: 14710522	2003
Caffeine as a neuroprotective adenosine receptor antagonist. The Annals of pharmacotherapy\| PubMed ID: 14982979	2004
Effect of DHEA glutamate release from synaptosomes of rats at different ages. Neurochemical research\| PubMed ID: 15002728	2004
Anticonvulsant effect of GMP depends on its conversion to guanosine. Brain research\| PubMed ID: 15044076	2004
Characterization of imido [8-(3)H] guanosine 5'-triphosphate binding sites to rat brain membranes. Neurochemical research\| PubMed ID: 15098945	2004
Ontogenetic profile of glutamate uptake in brain structures slices from rats: sensitivity to guanosine. Mechanisms of ageing and development\| PubMed ID: 15246742	2004
High extracellular K+ levels stimulate acetate oxidation in brain slices from well and malnourished rats. Neurochemical research\| PubMed ID: 15260133	2004
Glutaric acid stimulates glutamate binding and astrocytic uptake and inhibits vesicular glutamate uptake in forebrain from young rats. Neurochemistry international\| PubMed ID: 15337307	2004
Biochemical brain markers and purinergic parameters in rat CSF after seizure induced by pentylenetetrazol. Brain research bulletin\| PubMed ID: 15464860	2004
The effects of ebselen on [3H]glutamate uptake by synaptic vesicles from rat brain. Brain research\| PubMed ID: 15494171	2004
Increased locomotor response to amphetamine, but not other psychostimulants, in adult mice submitted to a low-protein diet. Physiology & behavior\| PubMed ID: 15501499	2004
Changes in S100B cerebrospinal fluid levels of rats subjected to predator stress. Brain research\| PubMed ID: 15527746	2004
Gestational and postnatal malnutrition affects sensitivity of young rats to picrotoxin and quinolinic acid and uptake of GABA by cortical and hippocampal slices. Brain research. Developmental brain research\| PubMed ID: 15707671	2005
The ischemic rat heart releases S100B. Life sciences\| PubMed ID: 15921704	2005
Cinnarizine has an atypical antipsychotic profile in animal models of psychosis. Journal of psychopharmacology (Oxford, England)\| PubMed ID: 15982988	2005
Effects of glutamate transporter and receptor ligands on neuronal glutamate uptake. Neuroscience research\| PubMed ID: 16011854	2005
Serum S100B levels in patients with neural tube defects. Clinica chimica acta; international journal of clinical chemistry\| PubMed ID: 16143320	2006
Exercise affects glutamate receptors in postsynaptic densities from cortical mice brain. Brain research\| PubMed ID: 16298350	2005
Acute and chronic electroconvulsive shock in rats: effects on peripheral markers of neuronal injury and glial activity. Life sciences\| PubMed ID: 16413036	2006
Glutamate uptake is stimulated by extracellular S100B in hippocampal astrocytes. Cellular and molecular neurobiology\| PubMed ID: 16633903	2006
A simple webcam-based approach for the measurement of rodent locomotion and other behavioural parameters. Journal of neuroscience methods\| PubMed ID: 16701901	2006
Effect of 2-deoxy-D-glucose on aminoacids metabolism in rats' cerebral cortex slices. Neurochemical research\| PubMed ID: 16733818	2006
The sesquiterpenes polygodial and drimanial in vitro affect glutamatergic transport in rat brain. Neurochemical research\| PubMed ID: 16733820	2006
Beta-amyloid treatment sensitizes mice to amphetamine-induced locomotion but reduces response to caffeine. Neuro-degenerative diseases\| PubMed ID: 16908972	2004
Methylmercury induces oxidative injury, alterations in permeability and glutamine transport in cultured astrocytes. Brain research\| PubMed ID: 17182013	2007
Naturally occurring compounds affect glutamatergic neurotransmission in rat brain. Neurochemical research\| PubMed ID: 17577666	2007
Age and brain structural related effects of glutaric and 3-hydroxyglutaric acids on glutamate binding to plasma membranes during rat brain development. Cellular and molecular neurobiology\| PubMed ID: 17786551	2007
Proposal of a guanine-based purinergic system in the mammalian central nervous system. Pharmacology & therapeutics\| PubMed ID: 17884172	2007
Duration of environmental enrichment influences the magnitude and persistence of its behavioral effects on mice. Physiology & behavior\| PubMed ID: 17949760	2008
Evidence that glutaric acid reduces glutamate uptake by cerebral cortex of infant rats. Life sciences\| PubMed ID: 17963786	2007
Western style diet impairs entrance of blood-borne insulin-like growth factor-1 into the brain. Neuromolecular medicine\| PubMed ID: 17999206	2007
Prenatal methylmercury exposure hampers glutathione antioxidant system ontogenesis and causes long-lasting oxidative stress in the mouse brain. Toxicology and applied pharmacology\| PubMed ID: 18023834	2008
Profile of glutamate uptake and cellular viability in hippocampal slices exposed to oxygen and glucose deprivation: developmental aspects and protection by guanosine. Brain research\| PubMed ID: 18053975	2008
Effects of undernutrition on glutamatergic parameters in the cerebral cortex of young rats. Physiology & behavior\| PubMed ID: 18485424	2008
Morphological changes in hippocampal astrocytes induced by environmental enrichment in mice. Brain research\| PubMed ID: 19374889	2009
Gestational and postnatal low protein diet alters insulin sensitivity in female rats. Experimental biology and medicine (Maywood, N.J.)\| PubMed ID: 19934364	2009
Algorithms to predict cerebral malaria in murine models using the SHIRPA protocol. Malaria journal\| PubMed ID: 20334682	2010
Agrp neurons mediate Sirt1's action on the melanocortin system and energy balance: roles for Sirt1 in neuronal firing and synaptic plasticity. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 20810901	2010
Structure-activity relationship of flavonoids derived from medicinal plants in preventing methylmercury-induced mitochondrial dysfunction. Environmental toxicology and pharmacology\| PubMed ID: 21127717	2010
Enriched environment effects on behavior, memory and BDNF in low and high exploratory mice. Physiology & behavior\| PubMed ID: 21236277	2011
Differences in spatio-temporal behavior of zebrafish in the open tank paradigm after a short-period confinement into dark and bright environments. PloS one\| PubMed ID: 21559304	2011
37 years of scientific activity in a Biochemistry Department in Brazil: patterns of growth and factors leading to increased productivity. Anais da Academia Brasileira de Ciencias\| PubMed ID: 21739081	2011
Motor impairment induced by oral exposure to methylmercury in adult mice. Environmental toxicology and pharmacology\| PubMed ID: 21783473	2005
Evidence that hyperprolinemia alters glutamatergic homeostasis in rat brain: neuroprotector effect of guanosine. Neurochemical research\| PubMed ID: 21935728	2012
Ω3-Polyunsaturated fatty acids prevent lipoperoxidation, modulate antioxidant enzymes, and reduce lipid content but do not alter glycogen metabolism in the livers of diabetic rats fed on a h... Molecular and cellular biochemistry\| PubMed ID: 21989716	2012
Behavioral effects of taurine pretreatment in zebrafish acutely exposed to ethanol. Neuropharmacology\| PubMed ID: 22634362	2012
AgRP neurons regulate development of dopamine neuronal plasticity and nonfood-associated behaviors. Nature neuroscience\| PubMed ID: 22729177	2012
Riluzole increases glutamate uptake by cultured C6 astroglial cells. International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience\| PubMed ID: 23777615	2013
Topographical analysis of reactive zinc in the central nervous system of adult zebrafish (Danio rerio). Zebrafish\| PubMed ID: 23829199	2013
Evaluation of spontaneous recovery of behavioral and brain injury profiles in zebrafish after hypoxia. Behavioural brain research\| PubMed ID: 23867150	2013
Anxiolytic effects of diphenyl diselenide on adult zebrafish in a novelty paradigm. Progress in neuro-psychopharmacology & biological psychiatry\| PubMed ID: 24936773	2014
Antioxidant effects of JM-20 on rat brain mitochondria and synaptosomes: mitoprotection against Ca²⁺-induced mitochondrial impairment. Brain research bulletin\| PubMed ID: 25305343	2014
The effects of JM-20 on the glutamatergic system in synaptic vesicles, synaptosomes and neural cells cultured from rat brain. Neurochemistry international\| PubMed ID: 25617730	2015
Original mechanisms of antipsychotic action by the indole alkaloid alstonine (Picralima nitida). Phytomedicine : international journal of phytotherapy and phytopharmacology\| PubMed ID: 25636871	2015
High phosphate serum levels correlate with the severity of experimental severe acute pancreatitis: insight into the purinergic system. Pancreas\| PubMed ID: 25815645	2015
Long-term NMDAR antagonism correlates reduced astrocytic glutamate uptake with anxiety-like phenotype. Frontiers in cellular neuroscience\| PubMed ID: 26089779	2015
Ovotoxicants 4-vinylcyclohexene 1,2-monoepoxide and 4-vinylcyclohexene diepoxide disrupt redox status and modify different electrophile sensitive target enzymes and genes in Drosophila melan... Redox biology\| PubMed ID: 26117601	2015
Influence of diphenyl diselenide on chlorpyrifos-induced toxicity in Drosophila melanogaster. Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS)\| PubMed ID: 26302912	2015
Neuroprotection by JM-20 against oxygen-glucose deprivation in rat hippocampal slices: Involvement of the Akt/GSK-3β pathway. Neurochemistry international\| PubMed ID: 26361722	2015
Intranasal guanosine administration presents a wide therapeutic time window to reduce brain damage induced by permanent ischemia in rats. Purinergic signalling\| PubMed ID: 26695181	2016
Guanosine Anxiolytic-Like Effect Involves Adenosinergic and Glutamatergic Neurotransmitter Systems. Molecular neurobiology\| PubMed ID: 26742520	2017
Brain zinc chelation by diethyldithiocarbamate increased the behavioral and mitochondrial damages in zebrafish subjected to hypoxia. Scientific reports\| PubMed ID: 26854133	2016
Neuroprotection of luteolin against methylmercury-induced toxicity in lobster cockroach Nauphoeta cinerea. Environmental toxicology and pharmacology\| PubMed ID: 26905302	2016
Guanosine Exerts Neuroprotective Effect in an Experimental Model of Acute Ammonia Intoxication. Molecular neurobiology\| PubMed ID: 27052954	2017
Corrigendum: Long-term NMDAR antagonism correlates reduced astrocytic glutamate uptake with anxiety-like phenotype. Frontiers in cellular neuroscience\| PubMed ID: 27147966	2016
Neurobehavioral and biochemical changes in Nauphoeta cinerea following dietary exposure to chlorpyrifos. Pesticide biochemistry and physiology\| PubMed ID: 27155480	2016
Antimicrobial Activity and Modulatory Effect of Essential Oil from the Leaf of Rhaphiodon echinus (Nees & Mart) Schauer on Some Antimicrobial Drugs. Molecules (Basel, Switzerland)\| PubMed ID: 27338314	2016
Scientific Performance of Brazilian Researchers in Pharmacology with grants from CNPq: A comparative study within the Brazilian categories. Anais da Academia Brasileira de Ciencias\| PubMed ID: 27556222	2016
How does zebrafish support new strategies for neuroprotection and neuroregeneration in hypoxia-related diseases? Neural regeneration research\| PubMed ID: 27630683	2016
ZIKA Virus and Neuroscience: the Need for a Translational Collaboration. Molecular neurobiology\| PubMed ID: 28185126	2018
Olfactory bulbectomy in mice triggers transient and long-lasting behavioral impairments and biochemical hippocampal disturbances. Progress in neuro-psychopharmacology & biological psychiatry\| PubMed ID: 28223107	2017
Cortical Bilateral Adaptations in Rats Submitted to Focal Cerebral Ischemia: Emphasis on Glial Metabolism. Molecular neurobiology\| PubMed ID: 28271402	2018
Mitochondrial involvement in memory impairment induced by scopolamine in rats. Neurological research\| PubMed ID: 28398193	2017
Evaluation of zinc effect on cadmium action in lipid peroxidation and metallothionein levels in the brain. Toxicology reports\| PubMed ID: 28962421	2015
Antioxidant and Neuroprotective Effects of KM-34, A Novel Synthetic Catechol, Against Oxidative Stress-Induced Neurotoxicity. Drug research\| PubMed ID: 29100263	2018
JM-20 Treatment After MCAO Reduced Astrocyte Reactivity and Neuronal Death on Peri-infarct Regions of the Rat Brain. Molecular neurobiology\| PubMed ID: 29725905	2019
Multi-targeting effects of a new synthetic molecule (JM-20) in experimental models of cerebral ischemia. Pharmacological reports : PR\| PubMed ID: 29933207	2018
Dietary co-exposure to methylmercury and monosodium glutamate disrupts cellular and behavioral responses in the lobster cockroach, Nauphoeta cinerea model. Environmental toxicology and pharmacology\| PubMed ID: 30300794	2018
Zika Virus Infection of Human Mesenchymal Stem Cells Promotes Differential Expression of Proteins Linked to Several Neurological Diseases. Molecular neurobiology\| PubMed ID: 30377986	2019
Memantine mediates astrocytic activity in response to excitotoxicity induced by PP2A inhibition. Neuroscience letters\| PubMed ID: 30586637	2019
Behavioral, Neurochemical and Brain Oscillation Abnormalities in an Experimental Model of Acute Liver Failure. Neuroscience\| PubMed ID: 30654003	2019
Caffeine and cannabinoid receptors modulate impulsive behavior in an animal model of attentional deficit and hyperactivity disorder. The European journal of neuroscience\| PubMed ID: 30667546	2019
The astrocyte biochemistry. Seminars in cell & developmental biology\| PubMed ID: 30951895	2019
ZIKAVID-Zika virus infection database: a new platform to analyze the molecular impact of Zika virus infection. Journal of neurovirology\| PubMed ID: 31512145	2020
Association between Zika virus and future neurological diseases. Journal of the neurological sciences\| PubMed ID: 31835212	2020
Acute Liver Failure Induces Glial Reactivity, Oxidative Stress and Impairs Brain Energy Metabolism in Rats. Frontiers in molecular neuroscience\| PubMed ID: 31998076	2019
Modified expression of antioxidant genes in lobster cockroach, Nauphoeta cinerea exposed to methylmercury and monosodium glutamate. Chemico-biological interactions\| PubMed ID: 32007422	2020
Amyloid-β oligomers in cellular models of Alzheimer's disease. Journal of neurochemistry\| PubMed ID: 32320074	2020
Guanosine fast onset antidepressant-like effects in the olfactory bulbectomy mice model. Scientific reports\| PubMed ID: 32439951	2020
S100B protein and neuron-specific enolase as predictors of postoperative cognitive dysfunction in aged dogs: a case-control study. Veterinary anaesthesia and analgesia\| PubMed ID: 32800537	2020
Guanosine enhances glutamate uptake and oxidation, preventing oxidative stress in mouse hippocampal slices submitted to high glutamate levels. Brain research\| PubMed ID: 32866546	2020
Dietary omega-3 fatty acids prevent neonatal seizure-induced early alterations in the hippocampal glutamatergic system and memory deficits in adulthood. Nutritional neuroscience\| PubMed ID: 33107813	2020
PET Imaging as a Tool for Assessing COVID-19 Brain Changes. Trends in neurosciences\| PubMed ID: 33131922	2020
Novel arylidene malonate derivative, KM-34, showed neuroprotective effects on in vitro and in vivo models of ischemia/reperfusion. European journal of pharmacology\| PubMed ID: 33722590	2021
About the source and consequences of F-FDG brain PET hypometabolism in short and long COVID-19. European journal of nuclear medicine and molecular imaging\| PubMed ID: 33813593	2021
Effects of intranasal guanosine administration on brain function in a rat model of ischemic stroke. Purinergic signalling\| PubMed ID: 33834349	2021
Allopurinol for fibromyalgia pain in adults: A randomized controlled trial. Pain practice : the official journal of World Institute of Pain\| PubMed ID: 33864725	2021
Zika Virus Infection Associated with Autism Spectrum Disorder: A Case Report. Neuroimmunomodulation\| PubMed ID: 34082423	2021
Allopurinol attenuates postoperative pain and modulates the purinergic system in patients undergoing abdominal hysterectomy: a randomized controlled trial. Journal of anesthesia\| PubMed ID: 34390392	2021
Antidepressant-Like Effects of Chronic Guanosine in the Olfactory Bulbectomy Mouse Model. Frontiers in psychiatry\| PubMed ID: 34421682	2021
JM-20 treatment prevents neuronal damage and memory impairment induced by aluminum chloride in rats. Neurotoxicology\| PubMed ID: 34481871	2021