creation-two-saccular-elastase-digested-aneurysms-with-different

Creation of Two Saccular Elastase-Digested Aneurysms with Different Hemodynamics in One Rabbit

Preclinical animal models with hemodynamic, morphologic, and histologic characteristics close to human intracranial aneurysms play a key role in the ...

using-cell-tracer-injection-to-investigate-origin-neointima-forming

Using a Cell-Tracer Injection to Investigate the Origin of Neointima-Forming Cells in a Rat Saccular Side Wall Model

Microsurgical clipping creates a subsequent barrier of blood flow into intracranial aneurysms, whereas endovascular treatment relies on neointima and ...

Kantonsspital Aarau

University of Bern

Endovascular aneurysm treatment relies on a biological process, including cell migration for thrombus organization and growth of a neointima. To better understand aneurysm healing, our study explores the origin of neointima-forming and thrombus-organizing cells in a rat saccular sidewall aneurysm model.

Patterns of Neointima Formation After Coil or Stent Treatment in a Rat Saccular Sidewall Aneurysm Model.

Aneurysm wall degeneration is linked to growth and rupture. To address the effect of aspirin (ASA) on aneurysm formation under various wall conditions, this issue was analyzed in a novel rabbit bifurcation model.

Aspirin treatment prevents inflammation in experimental bifurcation aneurysms in New Zealand White rabbits.

Unlike clipping that forms an immediate barrier of blood flow into intracranial aneurysms, endovascular treatments rely on thrombus organization and neointima formation. Therefore, a continuous endothelial cell layer is crucial to prevent blood flow in the former aneurysm. This study investigates the origin of endothelial cells in the neointima of endovascular treated aneurysms, specifically whether cells from the parent artery play a role in neointima formation.

ArticleTotal : 2	Year
Publication title Cited by 2	2021
Publication title Cited by 2	2022

Article	Year
Patterns of Neointima Formation After Coil or Stent Treatment in a Rat Saccular Sidewall Aneurysm Model. Stroke\| PubMed ID: 33504186	2021
Aspirin treatment prevents inflammation in experimental bifurcation aneurysms in New Zealand White rabbits. Journal of neurointerventional surgery\| PubMed ID: 33785639	2021
Parent artery-initiated and stent-mediated neointima formation in a rat saccular side wall model. Journal of neurointerventional surgery\| PubMed ID: 35110397	2022

Gwendoline Boillat

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