Sean S. Davies

Division of Clinical Pharmacology, Vanderbilt University Medical Center

Affiliated withVanderbilt University Medical Center

Research Area

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title Cited by 3	2021

Other Publications

Article	Year
Hydrolysis of bimatoprost (Lumigan) to its free acid by ocular tissue in vitro. Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics\| PubMed ID: 12648303	2003
Isoketals: highly reactive gamma-ketoaldehydes formed from the H2-isoprostane pathway. Chemistry and physics of lipids\| PubMed ID: 15037155	2004
Localization of isoketal adducts in vivo using a single-chain antibody. Free radical biology & medicine\| PubMed ID: 15082070	2004
Quantification of dinor, dihydro metabolites of F2-isoprostanes in urine by liquid chromatography/tandem mass spectrometry. Analytical biochemistry\| PubMed ID: 16309621	2006
Pyridoxamine analogues scavenge lipid-derived gamma-ketoaldehydes and protect against H2O2-mediated cytotoxicity. Biochemistry\| PubMed ID: 17176098	2006
Amitriptyline activates cardiac ryanodine channels and causes spontaneous sarcoplasmic reticulum calcium release. Molecular pharmacology\| PubMed ID: 18845675	2009
Ischemia/reperfusion unveils impaired capacity of older adults to restrain oxidative insult. Free radical biology & medicine\| PubMed ID: 19596063	2009
F2-isoprostanes as an indicator and risk factor for coronary heart disease. Free radical biology & medicine\| PubMed ID: 21126576	2011
Treatment with a γ-ketoaldehyde scavenger prevents working memory deficits in hApoE4 mice. Journal of Alzheimer's disease : JAD\| PubMed ID: 21709376	2011
Lipid peroxidation generates biologically active phospholipids including oxidatively N-modified phospholipids. Chemistry and physics of lipids\| PubMed ID: 24704586	2014
DC isoketal-modified proteins activate T cells and promote hypertension. The Journal of clinical investigation\| PubMed ID: 25244096	2014
Immune activation caused by vascular oxidation promotes fibrosis and hypertension. The Journal of clinical investigation\| PubMed ID: 26595812	2016
Effect of Drug Therapy on Net Cholesterol Efflux Capacity of High-Density Lipoprotein-Enriched Serum in Rheumatoid Arthritis. Arthritis & rheumatology (Hoboken, N.J.)\| PubMed ID: 26991245	2016
Microbial metabolism of dietary components to bioactive metabolites: opportunities for new therapeutic interventions. Genome medicine\| PubMed ID: 27102537	2016
Accumulation of isolevuglandin-modified protein in normal and fibrotic lung. Scientific reports\| PubMed ID: 27118599	2016
Dendritic cells and isolevuglandins in immunity, inflammation, and hypertension. American journal of physiology. Heart and circulatory physiology\| PubMed ID: 27986660	2017
Net cholesterol efflux capacity of HDL enriched serum and coronary atherosclerosis in rheumatoid arthritis. IJC metabolic & endocrine\| PubMed ID: 28243578	2016
Leptogenic effects of NAPE require activity of NAPE-hydrolyzing phospholipase D. Journal of lipid research\| PubMed ID: 28596183	2017
Modification by isolevuglandins, highly reactive γ-ketoaldehydes, deleteriously alters high-density lipoprotein structure and function. The Journal of biological chemistry\| PubMed ID: 29712723	2018
Isolevuglandins and cardiovascular disease. Prostaglandins & other lipid mediators\| PubMed ID: 30296489	2018
Simplified LC/MS assay for the measurement of isolevuglandin protein adducts in plasma and tissue samples. Analytical biochemistry\| PubMed ID: 30458125	2019
Administration of N-Acyl-Phosphatidylethanolamine Expressing Bacteria to Low Density Lipoprotein Receptor Mice Improves Indices of Cardiometabolic Disease. Scientific reports\| PubMed ID: 30674978	2019
Two-week administration of engineered Escherichia coli establishes persistent resistance to diet-induced obesity even without antibiotic pre-treatment. Applied microbiology and biotechnology\| PubMed ID: 31203417	2019
Arachidonic Acid Kills Staphylococcus aureus through a Lipid Peroxidation Mechanism. mBio\| PubMed ID: 31575763	2019
Modified sites and functional consequences of 4-oxo-2-nonenal adducts in HDL that are elevated in familial hypercholesterolemia. The Journal of biological chemistry\| PubMed ID: 31666337	2019
Symmetrically substituted dichlorophenes inhibit -acyl-phosphatidylethanolamine phospholipase D. The Journal of biological chemistry\| PubMed ID: 32284327	2020
Progressively decreasing plasma high-density lipoprotein cholesterol levels preceding diagnosis of smoldering myeloma. Journal of clinical lipidology\| PubMed ID: 32376310	2020
Pro-inflammatory HDL in women with obesity and nonalcoholic steatohepatitis. Obesity research & clinical practice\| PubMed ID: 32595023	2020
Reactive Dicarbonyl Scavenging Effectively Reduces MPO-Mediated Oxidation of HDL and Restores PON1 Activity. Nutrients\| PubMed ID: 32629758	2020
Engineering the gut microbiota to treat chronic diseases. Applied microbiology and biotechnology\| PubMed ID: 32696297	2020
Sodium activates human monocytes via the NADPH oxidase and isolevuglandin formation. Cardiovascular research\| PubMed ID: 33038226	2021
Kidney injury-mediated disruption of intestinal lymphatics involves dicarbonyl-modified lipoproteins. Kidney international\| PubMed ID: 34102217	2021