David D. Y. Chen

Department of Chemistry, University of British Columbia

Affiliated withUniversity of British Columbia

Research Area

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title Cited by 3	2021

Other Publications

Article	Year
Accurately describing weak analyte-additive interactions by capillary electrophoresis. Electrophoresis\| PubMed ID: 11920872	2002
Affinity capillary electrophoresis using a low-concentration additive with the consideration of relative mobilities. Analytical chemistry\| PubMed ID: 11985325	2002
Univalent salts as modifiers in micellar capillary electrophoresis. Electrophoresis\| PubMed ID: 12116136	2002
Proton and hydroxide ion mobility in capillary electrophoresis. Analytical chemistry\| PubMed ID: 12141650	2002
An atmospheric pressure ion lens that improves nebulizer assisted electrospray ion sources. Journal of the American Society for Mass Spectrometry\| PubMed ID: 12216730	2002
Multiple sprayer system for high-throughput electrospray ionization mass spectrometry. Rapid communications in mass spectrometry : RCM\| PubMed ID: 12362391	2002
Molecular interaction in capillary electrophoresis. Current opinion in biotechnology\| PubMed ID: 12566012	2003
Optimization of cellular nucleotide extraction and sample preparation for nucleotide pool analyses using capillary electrophoresis. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences\| PubMed ID: 12668076	2003
A quantitative study of continuous flow-counterbalanced capillary electrophoresis for sample purification. Electrophoresis\| PubMed ID: 12973791	2003
Determination of shapes and maximums of analyte peaks based on solute mobilities in capillary electrophoresis. Analytical chemistry\| PubMed ID: 15018572	2004
Continuous electrophoretic purification of individual analytes from multicomponent mixtures. Analytical chemistry\| PubMed ID: 15080741	2004
General approach to high-efficiency simulation of affinity capillary electrophoresis. Analytical chemistry\| PubMed ID: 15679352	2005
Enumeration algorithm for determination of binding constants in capillary electrophoresis. Analytical chemistry\| PubMed ID: 15828775	2005
Behavior of interacting species in capillary electrophoresis described by mass transfer equation. Analytical chemistry\| PubMed ID: 16536418	2006
Systematic optimization of exhaustive electrokinetic injection combined with micellar sweeping in capillary electrophoresis. The Analyst\| PubMed ID: 17260072	2007
Computer simulation of different modes of ACE based on the dynamic complexation model. Electrophoresis\| PubMed ID: 17854123	2007
Capillary electrophoresis frontal analysis for characterization of alphavbeta3 integrin binding interactions. Analytical chemistry\| PubMed ID: 18366190	2008
Behavior of interacting species in vacancy affinity capillary electrophoresis described by mass balance equation. Electrophoresis\| PubMed ID: 18702059	2008
Twenty years of interface development for capillary electrophoresis-electrospray ionization-mass spectrometry. Analytica chimica acta\| PubMed ID: 18790125	2008
Field distribution in an electrospray ionization source determined by finite element method. Rapid communications in mass spectrometry : RCM\| PubMed ID: 19189352	2009
Rationale, design and baseline characteristics of the PRO-TECT II study: PROpofol CardioproTECTion for Type II diabetics: a randomized, controlled trial of high-dose propofol versus isoflura... Contemporary clinical trials\| PubMed ID: 19336262	2009
Target-achieved propofol concentration during on-pump cardiac surgery: a pilot dose-finding study. Canadian journal of anaesthesia = Journal canadien d'anesthesie\| PubMed ID: 19639375	2009
Propofol protects against hydrogen peroxide-induced injury in cardiac H9c2 cells via Akt activation and Bcl-2 up-regulation. Biochemical and biophysical research communications\| PubMed ID: 19703415	2009
Decoupling CE and ESI for a more robust interface with MS. Electrophoresis\| PubMed ID: 20196027	2010
Free fatty acids composition in adipocere of the Kwäday Dän Ts'ìnchí ancient remains found in a glacier. Journal of forensic sciences\| PubMed ID: 20384931	2010
Differences in myocardial PTEN expression and Akt signalling in type 2 diabetic and nondiabetic patients undergoing coronary bypass surgery. Clinical endocrinology\| PubMed ID: 21521253	2011
Mass transport in a micro flow-through vial of a junction-at-the-tip capillary electrophoresis-mass spectrometry interface. Analytical chemistry\| PubMed ID: 21528898	2011
A promising capillary electrophoresis-electrospray ionization-mass spectrometry method for carbohydrate analysis. Electrophoresis\| PubMed ID: 21792989	2011
Potential of two-dimensional electro-fluid-dynamic devices for continuous purification of multiple components from complex samples. Analytical chemistry\| PubMed ID: 21923103	2011
Flow-through microvial facilitating interface of capillary isoelectric focusing and electrospray ionization mass spectrometry. Analytical chemistry\| PubMed ID: 21972844	2011
Local delivery of antimicrobial peptides using self-organized TiO2 nanotube arrays for peri-implant infections. Journal of biomedical materials research. Part A\| PubMed ID: 22045618	2012
The cellular and molecular origin of reactive oxygen species generation during myocardial ischemia and reperfusion. Pharmacology & therapeutics\| PubMed ID: 22138603	2012
A simple and robust LC-MS/MS method for quantification of free 3-nitrotyrosine in human plasma from patients receiving on-pump CABG surgery. Electrophoresis\| PubMed ID: 22451063	2012
Atmospheric pressure ion lens extends the stable operational region of an electrospray ion source for capillary electrophoresis-mass spectrometry. Electrophoresis\| PubMed ID: 22589113	2012
Monitoring potential prostate cancer biomarkers in urine by capillary electrophoresis-tandem mass spectrometry. Journal of chromatography. A\| PubMed ID: 22824219	2012
Capillary electrophoresis-mass spectrometry for analysis of complex samples. Proteomics\| PubMed ID: 22888086	2012
Capillary electrophoresis mass spectrometry for the characterization of O-acetylated N-glycans from fish serum. Analytical chemistry\| PubMed ID: 22971167	2012
Applications of capillary electrophoresis in characterizing recombinant protein therapeutics. Electrophoresis\| PubMed ID: 24123141	2014
Simple capillary electrophoresis-mass spectrometry method for complex glycan analysis using a flow-through microvial interface. Analytical chemistry\| PubMed ID: 24873509	2014
Comparison of sample introduction methods for continuous chemical purification in two-dimensional electro-fluid-dynamic devices. Analytical chemistry\| PubMed ID: 25303032	2014
Propofol cardioprotection for on-pump aortocoronary bypass surgery in patients with type 2 diabetes mellitus (PRO-TECT II): a phase 2 randomized-controlled trial. Canadian journal of anaesthesia = Journal canadien d'anesthesie\| PubMed ID: 26721648	2016
Capture efficiency of dynamic pH junction focusing in capillary electrophoresis. Electrophoresis\| PubMed ID: 26949078	2016
Responses of plant calmodulin to endocytosis induced by rare earth elements. Chemosphere\| PubMed ID: 27081794	2016
Separation of Recombinant Therapeutic Proteins Using Capillary Gel Electrophoresis and Capillary Isoelectric Focusing. Methods in molecular biology (Clifton, N.J.)\| PubMed ID: 27473487	2016
Potential of capillary electrophoresis mass spectrometry for the characterization and monitoring of amine-derivatized naphthenic acids from oil sands process-affected water. Journal of environmental sciences (China)\| PubMed ID: 28007176	2016
Quantitative Nonaqueous Capillary Electrophoresis-Mass Spectrometry Method for Determining Active Ingredients in Plant Extracts. Analytical chemistry\| PubMed ID: 28208307	2017
Mobility-based correction for accurate determination of binding constants by capillary electrophoresis-frontal analysis. Electrophoresis\| PubMed ID: 28247914	2017
Electroosmotic Flow Dispersion of Large Molecules in Electrokinetic Migration. Analytical chemistry\| PubMed ID: 28699728	2017
A preliminary study on the effects of lanthanum (III) on plant vitronectin-like protein and its toxicological basis. Ecotoxicology and environmental safety\| PubMed ID: 28738206	2017
Abnormal pinocytosis and valence-variable behaviors of cerium suggested a cellular mechanism for plant yield reduction induced by environmental cerium. Environmental pollution (Barking, Essex : 1987)\| PubMed ID: 28738302	2017
Characterization of dicarboxylic naphthenic acid fraction compounds utilizing amide derivatization: Proof of concept. Rapid communications in mass spectrometry : RCM\| PubMed ID: 28944977	2017
Nonaqueous capillary electrophoresis mass spectrometry method for determining highly hydrophobic peptides. Electrophoresis\| PubMed ID: 28990192	2018
Different in vitro cellular responses to tamoxifen treatment in polydimethylsiloxane-based devices compared to normal cell culture. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences\| PubMed ID: 29073477	2017
Review of recent developments in determining volatile organic compounds in exhaled breath as biomarkers for lung cancer diagnosis. Analytica chimica acta\| PubMed ID: 29137702	2017
High throughput screening of phenoxy carboxylic acids with dispersive solid phase extraction followed by direct analysis in real time mass spectrometry. Analytica chimica acta\| PubMed ID: 29137704	2017
Capillary electrophoresis-mass spectrometry for targeted and untargeted analysis of the sub-5 kDa urine metabolome of patients with prostate or bladder cancer: A feasibility study. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences\| PubMed ID: 29334632	2018
Deducing disulfide patterns of cysteine-rich proteins using signature fragments produced by top-down mass spectrometry. The Analyst\| PubMed ID: 29362732	2018
Characterization of Athabasca lean oil sands and mixed surficial materials: Comparison of capillary electrophoresis/low-resolution mass spectrometry and high-resolution mass spectrometry. Rapid communications in mass spectrometry : RCM\| PubMed ID: 29486520	2018
Characterization of plant polysaccharides from Dendrobium officinale by multiple chromatographic and mass spectrometric techniques. Journal of chromatography. A\| PubMed ID: 29555359	2018
Parsing and Quantification of Raw Orbitrap Mass Spectrometer Data Using RawQuant. Journal of proteome research\| PubMed ID: 29682972	2018
Pressure-assisted capillary electrophoresis frontal analysis for faster binding constant determination. Electrophoresis\| PubMed ID: 29700847	2018
Electrochemical detection of microcystin-LR based on its deleterious effect on DNA. Talanta\| PubMed ID: 29759219	2018
Optimization of dynamic pH barrage junction focusing for weakly alkaline or zwitterionic analytes in capillary electrophoresis. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences\| PubMed ID: 30056269	2018
RawTools: Rapid and Dynamic Interrogation of Orbitrap Data Files for Mass Spectrometer System Management. Journal of proteome research\| PubMed ID: 30462513	2019
Mass spectrometry and affinity capillary electrophoresis for characterization of host-guest interactions. Journal of chromatography. A\| PubMed ID: 30686647	2019
Differential Hydrogen/Deuterium Exchange during Proteoform Separation Enables Characterization of Conformational Differences between Coexisting Protein States. Analytical chemistry\| PubMed ID: 30830762	2019
Simultaneous determination of multiple components in cigarettes by mechanochemical extraction and direct analysis in real time mass spectrometry in minutes. Analytica chimica acta\| PubMed ID: 30832920	2019
Quantitative analysis of microcystin variants by capillary electrophoresis mass spectrometry with dynamic pH barrage junction focusing. Electrophoresis\| PubMed ID: 30924152	2019
Magnetic nanoparticles speed up mechanochemical solid phase extraction with enhanced enrichment capability for organochlorines in plants. Analytica chimica acta\| PubMed ID: 31027534	2019
Evaluation of the binding of natural products with thrombin binding aptamer G-quadruplex using electrospray ionization mass spectrometry and spectroscopic methods. Talanta\| PubMed ID: 31036205	2019
Solvent-free high-throughput analysis of herbicides in environmental water. Analytica chimica acta\| PubMed ID: 31128759	2019
MALDI-imaging of early stage Xenopus laevis embryos. Talanta\| PubMed ID: 31357275	2019
Sorbent and solvent co-enhanced direct analysis in real time-mass spectrometry for high-throughput determination of trace pollutants in water. Talanta\| PubMed ID: 31816783	2020
Application of multisegment injection on quantification of creatinine and standard addition analysis of urinary 5-hydroxyindoleacetic acid simultaneously with creatinine normalization. Electrophoresis\| PubMed ID: 31850545	2020
Bottom-up proteomics of envelope proteins extracted from spinach chloroplast via high organic content CE-MS. Electrophoresis\| PubMed ID: 31994203	2020
Characterization of interaction between Bcl-2 oncogene promoter I-Motif DNA and flavonoids using electrospray ionization mass spectrometry and pressure-assisted capillary electrophoresis fro... Talanta\| PubMed ID: 32312433	2020
Determination of urinary prostaglandin E as a potential biomarker of ureteral stent associated inflammation. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences\| PubMed ID: 32315976	2020
Complementary Methods for de Novo Monoclonal Antibody Sequencing to Achieve Complete Sequence Coverage. Journal of proteome research\| PubMed ID: 32338916	2020
Dynamic pH barrage junction focusing of amino acids, peptides, and digested monoclonal antibodies in capillary electrophoresis-mass spectrometry. Electrophoresis\| PubMed ID: 32436592	2020
A hydrophilic two-dimensional titanium-based metal-organic framework nanosheets for specific enrichment of glycopeptides. Analytica chimica acta\| PubMed ID: 32439055	2020
Highly efficient enrichment of N-glycopeptides by two-dimensional Hf-based metal-organic framework nanosheets. The Analyst\| PubMed ID: 32441734	2020
Rapid determination of chemical composition in the particulate matter of cigarette mainstream smoke. Talanta\| PubMed ID: 32498828	2020
Enantioselective analysis in complex matrices using capillary electrophoresis-mass spectrometry: A case study of the botanical drug Corydalis Rhizoma. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences\| PubMed ID: 32531643	2020
Combining online size exclusion chromatography and electrospray ionization mass spectrometry to characterize plant polysaccharides. Carbohydrate polymers\| PubMed ID: 32747250	2020
Data-driven development of liquid chromatography-mass spectrometry methods for combined sample matrices. Talanta\| PubMed ID: 33379089	2021
Quantitative characterization of human oncogene promoter G-quadruplex DNA-ligand interactions using a combination of mass spectrometry and capillary electrophoresis. Electrophoresis\| PubMed ID: 33990994	2021