Nicole F. Liachko

Geriatrics Research Education and Clinical Center, Veterans Affairs Puget Sound Health Care System

Affiliated withVeterans Affairs Puget Sound Health Care System University of Washington

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title Cited by 9	2021

Other Publications

Article	Year
Phosphorylation promotes neurotoxicity in a Caenorhabditis elegans model of TDP-43 proteinopathy. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 21123567	2010
Dopamine D2 receptor antagonism suppresses tau aggregation and neurotoxicity. Biological psychiatry\| PubMed ID: 23140663	2013
CDC7 inhibition blocks pathological TDP-43 phosphorylation and neurodegeneration. Annals of neurology\| PubMed ID: 23424178	2013
Protein kinase CK-1 inhibitors as new potential drugs for amyotrophic lateral sclerosis. Journal of medicinal chemistry\| PubMed ID: 24592867	2014
The tau tubulin kinases TTBK1/2 promote accumulation of pathological TDP-43. PLoS genetics\| PubMed ID: 25473830	2014
Loss of RAD-23 Protects Against Models of Motor Neuron Disease by Enhancing Mutant Protein Clearance. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 26490867	2015
The phosphatase calcineurin regulates pathological TDP-43 phosphorylation. Acta neuropathologica\| PubMed ID: 27473149	2016
TDP-43/FUS in motor neuron disease: Complexity and challenges. Progress in neurobiology\| PubMed ID: 27693252	2016
Sertraline, Paroxetine, and Chlorpromazine Are Rapidly Acting Anthelmintic Drugs Capable of Clinical Repurposing. Scientific reports\| PubMed ID: 29343694	2018
Pathological phosphorylation of tau and TDP-43 by TTBK1 and TTBK2 drives neurodegeneration. Molecular neurodegeneration\| PubMed ID: 29409526	2018
Preventive action of benztropine on platinum-induced peripheral neuropathies and tumor growth. Acta neuropathologica communications\| PubMed ID: 30657060	2019
Motor neuron disease-associated loss of nuclear TDP-43 is linked to DNA double-strand break repair defects. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 30770445	2019
Tau tubulin kinases in proteinopathy. The FEBS journal\| PubMed ID: 31034749	2019
Resistance and resilience to Alzheimer's disease pathology are associated with reduced cortical pTau and absence of limbic-predominant age-related TDP-43 encephalopathy in a community-based ... Acta neuropathologica communications\| PubMed ID: 31174609	2019
Constitutive XBP-1s-mediated activation of the endoplasmic reticulum unfolded protein response protects against pathological tau. Nature communications\| PubMed ID: 31570707	2019
Genome wide analysis reveals heparan sulfate epimerase modulates TDP-43 proteinopathy. PLoS genetics\| PubMed ID: 31834878	2019
Activity of the poly(A) binding protein MSUT2 determines susceptibility to pathological tau in the mammalian brain. Science translational medicine\| PubMed ID: 31852801	2019
ARENA-based activity profiling of tau and TDP-43 transgenic . microPublication biology\| PubMed ID: 32724897	2020
Targeting nuclear protein TDP-43 by cell division cycle kinase 7 inhibitors: A new therapeutic approach for amyotrophic lateral sclerosis. European journal of medicinal chemistry\| PubMed ID: 33139113	2021
Adult onset pan-neuronal human tau tubulin kinase 1 expression causes severe cerebellar neurodegeneration in mice. Acta neuropathologica communications\| PubMed ID: 33228809	2020
Regulation of TDP-43 phosphorylation in aging and disease. GeroScience\| PubMed ID: 34032984	2021
Tau and TDP-43 synergy: a novel therapeutic target for sporadic late-onset Alzheimer's disease. GeroScience\| PubMed ID: 34185246	2021