Paul W. M. Fedak

Section of Cardiac Surgery, Cumming School of Medicine

Affiliated withCumming School of Medicine

Research Area

Biography

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title Cited by 5	2021

Other Publications

Article	Year
Reply: Final Common Pathway of Aortic Dilation?: Heterogeneity of Aortic Wall Property Causes the Aneurysmal Change. Journal of the American College of Cardiology\| PubMed ID: 26868701	2016
Bicuspid aortic valve aortopathy: mechanistic and clinical insights from recent studies. Current opinion in cardiology\| PubMed ID: 28182589	2017
Heparin Augmentation Enhances Bioactive Properties of Acellular Extracellular Matrix Scaffold. Tissue engineering. Part A\| PubMed ID: 28457186	2018
Adhesive-Enhanced Sternal Closure: Feasibility and Safety of Late Sternal Reentry. Case reports in surgery\| PubMed ID: 28634566	2017
The Cost of Frailty in Cardiac Surgery. The Canadian journal of cardiology\| PubMed ID: 28666616	2017
Evolution of Precision Medicine and Surgical Strategies for Bicuspid Aortic Valve-Associated Aortopathy. Frontiers in physiology\| PubMed ID: 28740468	2017
Bicuspid aortic valve-associated aortopathy: update on biomarkers. Current opinion in cardiology\| PubMed ID: 29095713	2018
Mind the Gap: Current Challenges and Future State of Heart Failure Care. The Canadian journal of cardiology\| PubMed ID: 29111107	2017
Perioperative evaluation of regional aortic wall shear stress patterns in patients undergoing aortic valve and/or proximal thoracic aortic replacement. The Journal of thoracic and cardiovascular surgery\| PubMed ID: 29248286	2018
Seeing a tree through the forest: Precision medicine tools can enhance donor allocation in heart transplantation. The Journal of thoracic and cardiovascular surgery\| PubMed ID: 29310930	2018
Bridging to heart transplant with extracorporeal membrane oxygenation: Good or VAD? The Journal of thoracic and cardiovascular surgery\| PubMed ID: 29310932	2018
Aortic diameter: The beginning of the end of an era. The Journal of thoracic and cardiovascular surgery\| PubMed ID: 29510930	2018
Aortic Valve Replacement in an Era of Rapid Innovation: Better the Devil You Know. Journal of the American College of Cardiology\| PubMed ID: 29598860	2018
Using Acellular Bioactive Extracellular Matrix Scaffolds to Enhance Endogenous Cardiac Repair. Frontiers in cardiovascular medicine\| PubMed ID: 29696148	2018
Human pericardial proteoglycan 4 (lubricin): Implications for postcardiotomy intrathoracic adhesion formation. The Journal of thoracic and cardiovascular surgery\| PubMed ID: 29859675	2018
The American Association for Thoracic Surgery consensus guidelines on bicuspid aortic valve-related aortopathy: Executive summary. The Journal of thoracic and cardiovascular surgery\| PubMed ID: 30011756	2018
The American Association for Thoracic Surgery consensus guidelines on bicuspid aortic valve-related aortopathy: Full online-only version. The Journal of thoracic and cardiovascular surgery\| PubMed ID: 30011777	2018
Aortic valve-mediated wall shear stress is heterogeneous and predicts regional aortic elastic fiber thinning in bicuspid aortic valve-associated aortopathy. The Journal of thoracic and cardiovascular surgery\| PubMed ID: 30060930	2018
Empagliflozin Prevents Worsening of Cardiac Function in an Experimental Model of Pressure Overload-Induced Heart Failure. JACC. Basic to translational science\| PubMed ID: 30062155	2017
Bioactive Extracellular Matrix Scaffold Promotes Adaptive Cardiac Remodeling and Repair. JACC. Basic to translational science\| PubMed ID: 30062163	2017
Modify, simplify, apply: Do we need preclinical models for surgical innovation? The Journal of thoracic and cardiovascular surgery\| PubMed ID: 30098807	2018
Make sternotomy great again. The Journal of thoracic and cardiovascular surgery\| PubMed ID: 30107920	2018
Commentary: Structural valve degeneration in the era of precision medicine. The Journal of thoracic and cardiovascular surgery\| PubMed ID: 30389129	2019
Coronary Bypass Surgery for Diabetes and Multivessel Disease: Forget the SYNTAX. Journal of the American College of Cardiology\| PubMed ID: 30522647	2018
Induction of human aortic myofibroblast-mediated extracellular matrix dysregulation: A potential mechanism of fluoroquinolone-associated aortopathy. The Journal of thoracic and cardiovascular surgery\| PubMed ID: 30528439	2019
Validating innovations to improve recovery after heart surgery. Annals of translational medicine\| PubMed ID: 30613588	2018
Targeting selected extracellular matrix components to attenuate cardiac fibrosis. Annals of translational medicine\| PubMed ID: 30613624	2018
Precision and targeted therapy in cardiac surgery. Journal of thoracic disease\| PubMed ID: 30631535	2018
Utilizing wall shear stress as a clinical biomarker for bicuspid valve-associated aortopathy. Current opinion in cardiology\| PubMed ID: 30633073	2019
Commentary: Using ex vivo modeling to validate technical innovations in cardiac surgery. The Journal of thoracic and cardiovascular surgery\| PubMed ID: 30857816	2019
Minimally invasive cardiac surgery and the importance of qualitative patient-centered metrics to guide innovations. The Journal of thoracic and cardiovascular surgery\| PubMed ID: 30871840	2019
Evolving Surgical Approaches to Bicuspid Aortic Valve Associated Aortopathy. Frontiers in cardiovascular medicine\| PubMed ID: 30886849	2019
Minimally invasive cardiac surgery presents challenges for design of randomized clinical trials. The Journal of thoracic and cardiovascular surgery\| PubMed ID: 30901801	2019
Acellular Extracellular Matrix Bioscaffolds for Cardiac Repair and Regeneration. Frontiers in cell and developmental biology\| PubMed ID: 31080800	2019
Gata6 Pericardial Cavity Macrophages Relocate to the Injured Heart and Prevent Cardiac Fibrosis. Immunity\| PubMed ID: 31315031	2019
On the 'cusp' of clinical feasibility: aortic wall shear stress derived non-invasively with 4D flow MRI. Journal of thoracic disease\| PubMed ID: 31463155	2019
Application of Bioengineered Materials in the Surgical Management of Heart Failure. Frontiers in cardiovascular medicine\| PubMed ID: 31482096	2019
Commentary: Cause or consequence? The influence of mitral regurgitation on post-myocardial infarction structural remodeling is better defined using a new rodent model. The Journal of thoracic and cardiovascular surgery\| PubMed ID: 31610958	2019
SKA-31, an activator of Ca-activated K channels, improves cardiovascular function in aging. Pharmacological research\| PubMed ID: 31707036	2020
Commentary: The promise of precision cardiovascular surgery. The Journal of thoracic and cardiovascular surgery\| PubMed ID: 31818427	2021
Direct Effects of Empagliflozin on Extracellular Matrix Remodelling in Human Cardiac Myofibroblasts: Novel Translational Clues to Explain EMPA-REG OUTCOME Results. The Canadian journal of cardiology\| PubMed ID: 31837891	2020
Promoting Cardiac Regeneration and Repair Using Acellular Biomaterials. Frontiers in bioengineering and biotechnology\| PubMed ID: 32363184	2020
Applications of a Specialty Bicuspid Aortic Valve Program: Clinical Continuity and Translational Collaboration. Journal of clinical medicine\| PubMed ID: 32380775	2020
Fluoroquinolone-Associated Type A Aortic Dissection in Alpha-1 Anti-Trypsin Deficiency. The Annals of thoracic surgery\| PubMed ID: 32492444	2020
Acellular bioscaffolds redirect cardiac fibroblasts and promote functional tissue repair in rodents and humans with myocardial injury. Scientific reports\| PubMed ID: 32528051	2020
The science of BAV aortopathy. Progress in cardiovascular diseases\| PubMed ID: 32599028	2020
Surgical management of the aorta in BAV patients. Progress in cardiovascular diseases\| PubMed ID: 32640281	2020
Commentary: The return on investment for cardiothoracic surgeon-scientists. The Journal of thoracic and cardiovascular surgery\| PubMed ID: 32859412	2020
Commentary: The mutation matters: Improving precision for surgical management of hereditary aortic syndromes. The Journal of thoracic and cardiovascular surgery\| PubMed ID: 32951878	2020
Commentary: Transplanting the powerhouse of the cell to enhance cardiopulmonary repair. The Journal of thoracic and cardiovascular surgery\| PubMed ID: 32980149	2020
Commentary: Fluoroquinolone antibiotics are antiaortic. The Journal of thoracic and cardiovascular surgery\| PubMed ID: 33293062	2020
Commentary: A picture is worth a thousand words: Improving surgical approaches using advanced multimodal cardiac imaging. The Journal of thoracic and cardiovascular surgery\| PubMed ID: 33642107	2021
Commentary: Past is Prologue - Leveraging Big Data to Optimize Future Operative Risk Prediction. Seminars in thoracic and cardiovascular surgery\| PubMed ID: 33662550	2021
Mechanical and Structural Remodeling of Cardiac Muscle after Aerobic and Resistance Exercise Training in Rats. Medicine and science in sports and exercise\| PubMed ID: 33731663	2021
Commentary: How to save and improve the lives of families with heritable aortic diseases. The Journal of thoracic and cardiovascular surgery\| PubMed ID: 33781592	2021
Commentary: The 4AT score-Reducing confusion about delirium diagnosis after cardiac surgery. The Journal of thoracic and cardiovascular surgery\| PubMed ID: 34217535	2021
Summary: international consensus statement on nomenclature and classification of the congenital bicuspid aortic valve and its aortopathy, for clinical, surgical, interventional and research ... European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery\| PubMed ID: 34292332	2021
International consensus statement on nomenclature and classification of the congenital bicuspid aortic valve and its aortopathy, for clinical, surgical, interventional and research purposes. European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery\| PubMed ID: 34293102	2021
International Consensus Statement on Nomenclature and Classification of the Congenital Bicuspid Aortic Valve and Its Aortopathy, for Clinical, Surgical, Interventional and Research Purposes. The Annals of thoracic surgery\| PubMed ID: 34304860	2021
Summary: International Consensus Statement on Nomenclature and Classification of the Congenital Bicuspid Aortic Valve and Its Aortopathy, for Clinical, Surgical, Interventional and Research ... The Annals of thoracic surgery\| PubMed ID: 34304861	2021
Summary: International consensus statement on nomenclature and classification of the congenital bicuspid aortic valve and its aortopathy, for clinical, surgical, interventional, and research... The Journal of thoracic and cardiovascular surgery\| PubMed ID: 34304894	2021
International consensus statement on nomenclature and classification of the congenital bicuspid aortic valve and its aortopathy, for clinical, surgical, interventional and research purposes. The Journal of thoracic and cardiovascular surgery\| PubMed ID: 34304896	2021
Aorta-specific DNA methylation patterns in cell-free DNA from patients with bicuspid aortic valve-associated aortopathy. Clinical epigenetics\| PubMed ID: 34321094	2021
Prevention of Post-Operative Adhesions: A Comprehensive Review of Present and Emerging Strategies. Biomolecules\| PubMed ID: 34356652	2021
Post-Operative Adhesions: A Comprehensive Review of Mechanisms. Biomedicines\| PubMed ID: 34440071	2021
Potential role of epicardial adipose tissue in coronary artery endothelial cell dysfunction in type 2 diabetes. FASEB journal : official publication of the Federation of American Societies for Experimental Biology\| PubMed ID: 34469050	2021