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<em>In vivo</em> Function of Differential Subsets of Cutaneous Dendritic Cells to Induce Th17 Immunity in Intradermal <em>Candida albicans</em> Infection

The skin is the outermost barrier organ in the body, which contains several types of dendritic cells (DCs), a group of professional antigen-presenting ...

Yonsei University College of Medicine

We present a patient diagnosed with skin sarcoidosis, breast cancer, pulmonary tuberculosis, and peritoneal sarcoidosis with a past history of colorectal cancer. During stage work up for breast cancer, suspicious lesions on peritoneum were observed in imaging studies. Considering our patient's history and imaging findings, we initially suspected peritoneal carcinomatosis. However, the peritoneal lesion was diagnosed as sarcoidosis in laparoscopic biopsy. This case demonstrates that abdominal sarcoidosis might be considered as a differential diagnosis when there is a lesion suspected of being peritoneal carcinomatosis with nontypical clinical presentations.

Abdominal Sarcoidosis Mimicking Peritoneal Carcinomatosis.

Cellular senescence and aging result in a reduced ability to manage persistent types of inflammation. Thus, the chronic low-level inflammation associated with aging phenotype is called "inflammaging". Inflammaging is not only related with age-associated chronic systemic diseases such as cardiovascular disease and diabetes, but also skin aging. As the largest organ of the body, skin is continuously exposed to external stressors such as UV radiation, air particulate matter, and human microbiome. In this review article, we present mechanisms for accumulation of senescence cells in different compartments of the skin based on cell types, and their association with skin resident immune cells to describe changes in cutaneous immunity during the aging process.

Article	Year
Abdominal Sarcoidosis Mimicking Peritoneal Carcinomatosis. Annals of coloproctology\| PubMed ID: 29742855	2018
Cellular Senescence and Inflammaging in the Skin Microenvironment. International journal of molecular sciences\| PubMed ID: 33917737	2021

Won Seok Roh

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