Jean Rommelaere

Tumour Virology Division F010, German Cancer Research Center (DKFZ)

Affiliated withGerman Cancer Research Center (DKFZ)

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title Cited by 8	2012

Other Publications

Article	Year
Suppression of metastatic hemangiosarcoma by a parvovirus MVMp vector transducing the IP-10 chemokine into immunocompetent mice. Cancer gene therapy\| PubMed ID: 11961666	2002
Specific interaction of the nonstructural protein NS1 of minute virus of mice (MVM) with [ACCA](2) motifs in the centre of the right-end MVM DNA palindrome induces hairpin-primed viral DNA r... The Journal of general virology\| PubMed ID: 12075084	2002
The NS2 proteins of parvovirus minute virus of mice are required for efficient nuclear egress of progeny virions in mouse cells. Journal of virology\| PubMed ID: 12239307	2002
Regulation of minute virus of mice NS1 replicative functions by atypical PKClambda in vivo. Journal of virology\| PubMed ID: 12477848	2003
Production of recombinant H1 parvovirus stocks devoid of replication-competent viruses. Human gene therapy\| PubMed ID: 12542845	2002
Chimeric and pseudotyped parvoviruses minimize the contamination of recombinant stocks with replication-competent viruses and identify a DNA sequence that restricts parvovirus H-1 in mouse c... Journal of virology\| PubMed ID: 12610161	2003
Oncolytic parvovirus H1 induces release of heat-shock protein HSP72 in susceptible human tumor cells but may not affect primary immune cells. Cancer gene therapy\| PubMed ID: 12768193	2003
Modulation of minute virus of mice cytotoxic activities through site-directed mutagenesis within the NS coding region. Journal of virology\| PubMed ID: 14610171	2003
The human small glutamine-rich TPR-containing protein is required for progress through cell division. Experimental cell research\| PubMed ID: 14729056	2004
Parvovirus H-1 infection of human glioma cells leads to complete viral replication and efficient cell killing. International journal of cancer. Journal international du cancer\| PubMed ID: 14735471	2004
Vectors based on autonomous parvoviruses: novel tools to treat cancer? The journal of gene medicine\| PubMed ID: 14978762	2004
Carrier cell-mediated delivery of oncolytic parvoviruses for targeting metastases. International journal of cancer. Journal international du cancer\| PubMed ID: 14999784	2004
Cancer gene therapy through autonomous parvovirus--mediated gene transfer. Current gene therapy\| PubMed ID: 15384939	2004
Selective alterations of the host cell architecture upon infection with parvovirus minute virus of mice. Virology\| PubMed ID: 15582663	2005
The infectivity and lytic activity of minute virus of mice wild-type and derived vector particles are strikingly different. Journal of virology\| PubMed ID: 15596824	2005
Expression profiling of human hepatoma cells reveals global repression of genes involved in cell proliferation, growth, and apoptosis upon infection with parvovirus H-1. Journal of virology\| PubMed ID: 15681429	2005
B1 lymphocytes and myeloid dendritic cells in lymphoid organs are preferential extratumoral sites of parvovirus minute virus of mice prototype strain expression. Journal of virology\| PubMed ID: 15731246	2005
Changes in gene expression profiles induced by parvovirus H-1 in human gastric cancer cells. Chinese journal of digestive diseases\| PubMed ID: 15904425	2005
Parvovirus H-1-induced tumor cell death enhances human immune response in vitro via increased phagocytosis, maturation, and cross-presentation by dendritic cells. Human gene therapy\| PubMed ID: 16076257	2005
Phosphorylation on Ser106 modulates the cellular functions of the SHOX homeodomain protein. Journal of molecular biology\| PubMed ID: 16325853	2006
Tumor suppressive activity of a variant isoform of manganese superoxide dismutase released by a human liposarcoma cell line. International journal of cancer. Journal international du cancer\| PubMed ID: 16550599	2006
NS1 interaction with CKII alpha: novel protein complex mediating parvovirus-induced cytotoxicity. Journal of virology\| PubMed ID: 16641266	2006
Oncolytic murine autonomous parvovirus, a candidate vector for glioma gene therapy, is innocuous to normal and immunocompetent mouse glial cells. Cell and tissue research\| PubMed ID: 16699801	2006
Human SGT interacts with Bag-6/Bat-3/Scythe and cells with reduced levels of either protein display persistence of few misaligned chromosomes and mitotic arrest. Experimental cell research\| PubMed ID: 16777091	2006
Humoral immune responses against minute virus of mice vectors. The journal of gene medicine\| PubMed ID: 16800041	2006
MCP-3 (CCL7) delivered by parvovirus MVMp reduces tumorigenicity of mouse melanoma cells through activation of T lymphocytes and NK cells. International journal of cancer. Journal international du cancer\| PubMed ID: 17154174	2007
Cytosolic activation of cathepsins mediates parvovirus H-1-induced killing of cisplatin and TRAIL-resistant glioma cells. Journal of virology\| PubMed ID: 17287256	2007
Combined oncolytic and vaccination activities of parvovirus H-1 in a metastatic tumor model. Oncology reports\| PubMed ID: 17487410	2007
A viral adaptor protein modulating casein kinase II activity induces cytopathic effects in permissive cells. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 17636126	2007
Parvovirus interference with intracellular signalling: mechanism of PKCeta activation in MVM-infected A9 fibroblasts. Cellular microbiology\| PubMed ID: 18042254	2008
Arming parvoviruses with CpG motifs to improve their oncosuppressive capacity. International journal of cancer. Journal international du cancer\| PubMed ID: 18360875	2008
Killing of p53-deficient hepatoma cells by parvovirus H-1 and chemotherapeutics requires promyelocytic leukemia protein. World journal of gastroenterology : WJG\| PubMed ID: 18609705	2008
Vesicular egress of non-enveloped lytic parvoviruses depends on gelsolin functioning. PLoS pathogens\| PubMed ID: 18704167	2008
Viral proteins killing tumor cells: new weapons in the fight against cancer. Cancer biology & therapy\| PubMed ID: 18769128	2008
Biophysical and biochemical characterization of a liposarcoma-derived recombinant MnSOD protein acting as an anticancer agent. International journal of cancer. Journal international du cancer\| PubMed ID: 18798256	2008
Improvement of gemcitabine-based therapy of pancreatic carcinoma by means of oncolytic parvovirus H-1PV. Clinical cancer research : an official journal of the American Association for Cancer Research\| PubMed ID: 19147756	2009
Ezrin-radixin-moesin family proteins are involved in parvovirus replication and spreading. Journal of virology\| PubMed ID: 19321616	2009
Oncolytic rat parvovirus H-1PV, a candidate for the treatment of human lymphoma: In vitro and in vivo studies. Molecular therapy : the journal of the American Society of Gene Therapy\| PubMed ID: 19367260	2009
SMAD4: a predictive marker of PDAC cell permissiveness for oncolytic infection with parvovirus H-1PV. International journal of cancer. Journal international du cancer\| PubMed ID: 19856310	2010
Activation of an antiviral response in normal but not transformed mouse cells: a new determinant of minute virus of mice oncotropism. Journal of virology\| PubMed ID: 19864388	2010
Parvovirus H1 selectively induces cytotoxic effects on human neuroblastoma cells. International journal of cancer. Journal international du cancer\| PubMed ID: 20087864	2010
Oncolytic parvoviruses as cancer therapeutics. Cytokine & growth factor reviews\| PubMed ID: 20211577	2010
Improved killing of human high-grade glioma cells by combining ionizing radiation with oncolytic parvovirus H-1 infection. Journal of biomedicine & biotechnology\| PubMed ID: 20224643	2010
Regression of advanced rat and human gliomas by local or systemic treatment with oncolytic parvovirus H-1 in rat models. Neuro-oncology\| PubMed ID: 20299703	2010
Through its nonstructural protein NS1, parvovirus H-1 induces apoptosis via accumulation of reactive oxygen species. Journal of virology\| PubMed ID: 20375165	2010
Enhancement of NK cell antitumor responses using an oncolytic parvovirus. International journal of cancer. Journal international du cancer\| PubMed ID: 20473905	2011
Sodium butyrate with UCN-01 has marked antitumour activity against cervical cancer cells. Anticancer research\| PubMed ID: 21036719	2010
Immune cells participate in the oncosuppressive activity of parvovirus H-1PV and are activated as a result of their abortive infection with this agent. Cancer biology & therapy\| PubMed ID: 21124075	2011
Therapeutic implications of the enhanced short and long-term cytotoxicity of radiation treatment followed by oncolytic parvovirus H-1 infection in high-grade glioma cells. Bioengineered bugs\| PubMed ID: 21468212	2010
The combined effects of oncolytic reovirus plus Newcastle disease virus and reovirus plus parvovirus on U87 and U373 cells inÂ vitro and inÂ vivo. Journal of neuro-oncology\| PubMed ID: 21607667	2011
Regression of glioma in rat models by intranasal application of parvovirus h-1. Clinical cancer research : an official journal of the American Association for Cancer Research\| PubMed ID: 21715567	2011
Interferon Î³ improves the vaccination potential of oncolytic parvovirus H-1PV for the treatment of peritoneal carcinomatosis in pancreatic cancer. Cancer biology & therapy\| PubMed ID: 22024742	2011
Activation of the human immune system by chemotherapeutic or targeted agents combined with the oncolytic parvovirus H-1. BMC cancer\| PubMed ID: 22029859	2011
Retargeting of rat parvovirus H-1PV to cancer cells through genetic engineering of the viral capsid. Journal of virology\| PubMed ID: 22258256	2012
Activation of a helper and not regulatory human CD4+ T cell response by oncolytic H-1 parvovirus. PloS one\| PubMed ID: 22359669	2012
Phase I/IIa study of intratumoral/intracerebral or intravenous/intracerebral administration of Parvovirus H-1 (ParvOryx) in patients with progressive primary or recurrent glioblastoma multif... BMC cancer\| PubMed ID: 22436661	2012