Xiaozhuo Chen

Department of Biological Sciences, Ohio University

Research Area

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title Cited by 3	2021

Other Publications

Article	Year
A ribozyme-mediated, gene "knockdown" strategy for the identification of gene function in zebrafish. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 9391103	1997
Seryl-histidine as an alternative DNA nicking agent in nick translation yields superior DNA probes and hybridizations. Bioorganic & medicinal chemistry\| PubMed ID: 11814854	2002
Tannic acid stimulates glucose transport and inhibits adipocyte differentiation in 3T3-L1 cells. The Journal of nutrition\| PubMed ID: 15671208	2005
Transcription regulation of the vegf gene by the BMP/Smad pathway in the angioblast of zebrafish embryos. Biochemical and biophysical research communications\| PubMed ID: 15721310	2005
Natural anti-diabetic compound 1,2,3,4,6-penta-O-galloyl-D-glucopyranose binds to insulin receptor and activates insulin-mediated glucose transport signaling pathway. Biochemical and biophysical research communications\| PubMed ID: 16137651	2005
Synthesis and structure-activity relationship study of antidiabetic penta-O-galloyl-D-glucopyranose and its analogues. Journal of medicinal chemistry\| PubMed ID: 16640344	2006
Antidiabetes and Anti-obesity Activity of Lagerstroemia speciosa. Evidence-based complementary and alternative medicine : eCAM\| PubMed ID: 18227906	2007
Regulation of G(1) arrest and apoptosis in hypoxia by PERK and GCN2-mediated eIF2alpha phosphorylation. Neoplasia (New York, N.Y.)\| PubMed ID: 20072654	2010
Novel inhibitors of basal glucose transport as potential anticancer agents. Bioorganic & medicinal chemistry letters\| PubMed ID: 20194024	2010
Small compound inhibitors of basal glucose transport inhibit cell proliferation and induce apoptosis in cancer cells via glucose-deprivation-like mechanisms. Cancer letters\| PubMed ID: 20678861	2010
Insulin receptor signaling activated by penta-O-galloyl-α-D: -glucopyranose induces p53 and apoptosis in cancer cells. Apoptosis : an international journal on programmed cell death\| PubMed ID: 21671008	2011
A novel small molecule 1,2,3,4,6-penta-O-galloyl-α-D-glucopyranose mimics the antiplatelet actions of insulin. PloS one\| PubMed ID: 22073153	2011
A small-molecule inhibitor of glucose transporter 1 downregulates glycolysis, induces cell-cycle arrest, and inhibits cancer cell growth in vitro and in vivo. Molecular cancer therapeutics\| PubMed ID: 22689530	2012
Synthesis and Antitumor Activity of Ellagic Acid Peracetate. ACS medicinal chemistry letters\| PubMed ID: 23185648	2012
Orally efficacious novel small molecule 6-chloro-6-deoxy-1,2,3,4-tetra-O-galloyl-α-D-glucopyranose selectively and potently stimulates insulin receptor and alleviates diabetes. Journal of molecular endocrinology\| PubMed ID: 23549408	2013
Constituents of an extract of Cryptocarya rubra housed in a repository with cytotoxic and glucose transport inhibitory effects. Journal of natural products\| PubMed ID: 24344605	2014
Biological and biomedical functions of Penta-O-galloyl-D-glucose and its derivatives. Journal of natural medicines\| PubMed ID: 24532420	2014
Extracellular ATP is internalized by macropinocytosis and induces intracellular ATP increase and drug resistance in cancer cells. Cancer letters\| PubMed ID: 24973521	2014
The Warburg effect: evolving interpretations of an established concept. Free radical biology & medicine\| PubMed ID: 25277420	2015
Salicylketoximes That Target Glucose Transporter 1 Restrict Energy Supply to Lung Cancer Cells. ChemMedChem\| PubMed ID: 26332543	2015
Novel 1,5-diphenyl-6-substituted 1H-pyrazolo[3,4-d]pyrimidin-4(5H)-ones induced apoptosis in RKO colon cancer cells. Journal of enzyme inhibition and medicinal chemistry\| PubMed ID: 26677729	2016
Extracellular ATP a New Player in Cancer Metabolism: NSCLC Cells Internalize ATP In Vitro and In Vivo Using Multiple Endocytic Mechanisms. Molecular cancer research : MCR\| PubMed ID: 27578770	2016
Cardiac Glycoside Constituents of Streblus asper with Potential Antineoplastic Activity. Journal of natural products\| PubMed ID: 27983842	2017
Extracellular ATP, as an energy and phosphorylating molecule, induces different types of drug resistances in cancer cells through ATP internalization and intracellular ATP level increase. Oncotarget\| PubMed ID: 29152126	2017
Extracellular and macropinocytosis internalized ATP work together to induce epithelial-mesenchymal transition and other early metastatic activities in lung cancer. Cancer cell international\| PubMed ID: 31582910	2019
Plant-derived glucose transport inhibitors with potential antitumor activity. Phytotherapy research : PTR\| PubMed ID: 31823431	2020
Cytotoxic and non-cytotoxic cardiac glycosides isolated from the combined flowers, leaves, and twigs of Streblus asper. Bioorganic & medicinal chemistry\| PubMed ID: 31953129	2020
The anti-diabetic effect of eight Lagerstroemia speciosa leaf extracts based on the contents of ellagitannins and ellagic acid derivatives. Food & function\| PubMed ID: 32003379	2020
Na/K-ATPase-Targeted Cytotoxicity of (+)-Digoxin and Several Semisynthetic Derivatives. Journal of natural products\| PubMed ID: 32096998	2020
Isosteres of ester derived glucose uptake inhibitors. Bioorganic & medicinal chemistry letters\| PubMed ID: 32736210	2020
Natural Compound α-PGG and Its Synthetic Derivative 6Cl-TGQ Alter Insulin Secretion: Evidence for Diminishing Glucose Uptake as a Mechanism. Diabetes, metabolic syndrome and obesity : targets and therapy\| PubMed ID: 33658814	2021
A small-molecule pan-class I glucose transporter inhibitor reduces cancer cell proliferation in vitro and tumor growth in vivo by targeting glucose-based metabolism. Cancer & metabolism\| PubMed ID: 33771231	2021