Edwin K. Jackson

Edwin K. Jackson

Department of Pharmacology and Chemical Biology, University of Pittsburgh

Affiliated withUniversity of Pittsburgh

Research Area

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JoVE Journal Publications

ArticleTotal : 1
Year
Mammary Epithelial and Endothelial Cell Spheroids as a Potential Functional <em>In vitro</em> Model for Breast Cancer Research
Publication title

Cited by 2

2021

Other Publications

Article
Year
Adenosine-mediated inhibition of the cytotoxic activity and cytokine production by activated natural killer cells.

Cancer research| PubMed ID: 16885379

2006
Sex hormones and hypertension.

Cardiovascular research| PubMed ID: 11861040

2002
2002
2002
2002
Expression of adenosine receptors in the preglomerular microcirculation.

American journal of physiology. Renal physiology| PubMed ID: 12060585

2002
2002
2-Hydroxyestradiol attenuates renal disease in chronic puromycin aminonucleoside nephropathy.

Journal of the American Society of Nephrology : JASN| PubMed ID: 12397044

2002
2003
2003
2003
Oviduct cells express the cyclic AMP-adenosine pathway.

Biology of reproduction| PubMed ID: 12724271

2003
Methylation of 2-hydroxyestradiol in isolated organs.

Hypertension (Dallas, Tex. : 1979)| PubMed ID: 12771046

2003
Rat models of the metabolic syndrome.

Methods in molecular medicine| PubMed ID: 12886760

2003
Renal extraction of angiotensin II.

The Journal of pharmacology and experimental therapeutics| PubMed ID: 14534364

2003
Adenosine biosynthesis in the collecting duct.

The Journal of pharmacology and experimental therapeutics| PubMed ID: 14560043

2003
2003
AT2 receptors attenuate AT1 receptor-induced phospholipase D activation in vascular smooth muscle cells.

The Journal of pharmacology and experimental therapeutics| PubMed ID: 14722318

2004
2-hydroxyestradiol is a prodrug of 2-methoxyestradiol.

The Journal of pharmacology and experimental therapeutics| PubMed ID: 14872091

2004
The extracellular cyclic AMP-adenosine pathway in renal physiology.

Annual review of physiology| PubMed ID: 14977414

2004
2004
2004
2004
Increased expression of the sodium transporter BSC-1 in spontaneously hypertensive rats.

The Journal of pharmacology and experimental therapeutics| PubMed ID: 15340004

2004
2004
2004
2004
2005
2005
Mechanism of the vascular angiotensin II/alpha2-adrenoceptor interaction.

The Journal of pharmacology and experimental therapeutics| PubMed ID: 15901799

2005
Characterization of the effects of adenosine receptor agonists on cerebral blood flow in uninjured and traumatically injured rat brain using continuous arterial spin-labeled magnetic resonan...

Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism| PubMed ID: 15931163

2005
2005
2005
Adenosine A1 receptor knockout mice develop lethal status epilepticus after experimental traumatic brain injury.

Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism| PubMed ID: 16121125

2006
Estradiol metabolites attenuate monocrotaline-induced pulmonary hypertension in rats.

Journal of cardiovascular pharmacology| PubMed ID: 16160593

2005
Gs protein-coupled adenosine receptor signaling and lytic function of activated NK cells.

Journal of immunology (Baltimore, Md. : 1950)| PubMed ID: 16177079

2005
2006
cAMP-adenosine pathway in the proximal tubule.

The Journal of pharmacology and experimental therapeutics| PubMed ID: 16527902

2006
2006
2006
A2A adenosine receptor protects tumors from antitumor T cells.

Proceedings of the National Academy of Sciences of the United States of America| PubMed ID: 16916931

2006
2006
The extracellular cAMP-adenosine pathway significantly contributes to the in vivo production of adenosine.

The Journal of pharmacology and experimental therapeutics| PubMed ID: 17028245

2007
2007
PPAR alpha agonists improve renal preservation in kidneys subjected to chronic in vitro perfusion: interaction with mannitol.

Transplant international : official journal of the European Society for Organ Transplantation| PubMed ID: 17291221

2007
Characterization of renal ecto-phosphodiesterase.

The Journal of pharmacology and experimental therapeutics| PubMed ID: 17308037

2007
2007
The pancreatohepatorenal cAMP-adenosine mechanism.

The Journal of pharmacology and experimental therapeutics| PubMed ID: 17314200

2007
2006
2007
2007
Emergency preservation and resuscitation with profound hypothermia, oxygen, and glucose allows reliable neurological recovery after 3 h of cardiac arrest from rapid exsanguination in dogs.

Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism| PubMed ID: 17622254

2008
Increases in cerebrospinal fluid caffeine concentration are associated with favorable outcome after severe traumatic brain injury in humans.

Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism| PubMed ID: 17684518

2008
2007
2007
2007
2007
2007
Effects of dipeptidyl peptidase iv inhibition on arterial blood pressure.

Clinical and experimental pharmacology & physiology| PubMed ID: 18047624

2008
Chronic noradrenaline increases renal expression of NHE-3, NBC-1, BSC-1 and aquaporin-2.

Clinical and experimental pharmacology & physiology| PubMed ID: 18177483

2008
Regulation of renal ectophosphodiesterase by protein kinase C and sodium diet.

The Journal of pharmacology and experimental therapeutics| PubMed ID: 18223197

2008
2008
Assessment of nerve stimulation-induced release of purines from mouse kidneys by tandem mass spectrometry.

The Journal of pharmacology and experimental therapeutics| PubMed ID: 18322147

2008
2008
2008
Identification and quantification of 2',3'-cAMP release by the kidney.

The Journal of pharmacology and experimental therapeutics| PubMed ID: 19033554

2009
2008
2009
2009
2009
2009
Multidrug resistance protein 4 mediates cAMP efflux from rat preglomerular vascular smooth muscle cells.

Clinical and experimental pharmacology & physiology| PubMed ID: 19671067

2010
Potential vascular actions of 2-methoxyestradiol.

Trends in endocrinology and metabolism: TEM| PubMed ID: 19734053

2009
2009
Extracellular 2',3'-cAMP is a source of adenosine.

The Journal of biological chemistry| PubMed ID: 19801686

2009
Increased ectonucleotidase expression and activity in regulatory T cells of patients with head and neck cancer.

Clinical cancer research : an official journal of the American Association for Cancer Research| PubMed ID: 19825957

2009
2010
2010
Extracellular 3',5'-cAMP-adenosine pathway inhibits glomerular mesangial cell growth.

The Journal of pharmacology and experimental therapeutics| PubMed ID: 20194527

2010
2010
2010
2010
2010
2010
2010
Candidate genes and mechanisms for 2-methoxyestradiol-mediated vasoprotection.

Hypertension (Dallas, Tex. : 1979)| PubMed ID: 20921434

2010
2011
2010
2011
2011
Role of sphingosine-1-phosphate in the renal medulla.

American journal of physiology. Renal physiology| PubMed ID: 21511695

2011
2',3'-cAMP, 3'-AMP, and 2'-AMP inhibit human aortic and coronary vascular smooth muscle cell proliferation via A2B receptors.

American journal of physiology. Heart and circulatory physiology| PubMed ID: 21622827

2011
Extracellular cAMP-adenosine pathways in the mouse kidney.

American journal of physiology. Renal physiology| PubMed ID: 21653635

2011
2011
2011
The 2',3'-cAMP-adenosine pathway.

American journal of physiology. Renal physiology| PubMed ID: 21937608

2011
2012
2012
2011
2011
The brain in vivo expresses the 2',3'-cAMP-adenosine pathway.

Journal of neurochemistry| PubMed ID: 22360621

2012
Modulation of bladder function by luminal adenosine turnover and A1 receptor activation.

American journal of physiology. Renal physiology| PubMed ID: 22552934

2012
2012
2012
Role of A1 receptors in renal sympathetic neurotransmission in the mouse kidney.

American journal of physiology. Renal physiology| PubMed ID: 22874760

2012
2012
2013
Extracellular guanosine regulates extracellular adenosine levels.

American journal of physiology. Cell physiology| PubMed ID: 23242185

2013
2013
2013
2013
In vivo cardiovascular pharmacology of 2',3'-cAMP, 2'-AMP, and 3'-AMP in the rat.

The Journal of pharmacology and experimental therapeutics| PubMed ID: 23759508

2013
2013
2013
2013
2013
2013
2013
2013
2013
2014
2014
Role of 2',3'-cyclic nucleotide 3'-phosphodiesterase in the renal 2',3'-cAMP-adenosine pathway.

American journal of physiology. Renal physiology| PubMed ID: 24808540

2014
Guanosine regulates adenosine levels in the kidney.

Physiological reports| PubMed ID: 24872359

2014
2014
The guanosine-adenosine interaction exists in vivo.

The Journal of pharmacology and experimental therapeutics| PubMed ID: 25002416

2014
2014
2014
Prevention of skin carcinogenesis by the β-blocker carvedilol.

Cancer prevention research (Philadelphia, Pa.)| PubMed ID: 25367979

2015
2015
2015
2015
The nuclear splicing factor RNA binding motif 5 promotes caspase activation in human neuronal cells, and increases after traumatic brain injury in mice.

Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism| PubMed ID: 25586139

2015
Emerging therapies in traumatic brain injury.

Seminars in neurology| PubMed ID: 25714870

2015
2015
2015
Schwann Cells Metabolize Extracellular 2',3'-cAMP to 2'-AMP.

The Journal of pharmacology and experimental therapeutics| PubMed ID: 25998049

2015
2015
2015
2015
2015
2015
2015
2-Methoxyestradiol blocks the RhoA/ROCK1 pathway in human aortic smooth muscle cells.

American journal of physiology. Endocrinology and metabolism| PubMed ID: 26487003

2015
2016
2016
Discovery and Roles of 2',3'-cAMP in Biological Systems.

Handbook of experimental pharmacology| PubMed ID: 26721674

2017
2016
Purines: forgotten mediators in traumatic brain injury.

Journal of neurochemistry| PubMed ID: 26809224

2016
2017
Estrogens in Men: Another Layer of Complexity of Estradiol Metabolism in Pulmonary Hypertension.

American journal of respiratory and critical care medicine| PubMed ID: 27174480

2016
8-Aminoguanosine and 8-Aminoguanine Exert Diuretic, Natriuretic, Glucosuric, and Antihypertensive Activity.

The Journal of pharmacology and experimental therapeutics| PubMed ID: 27679494

2016
2016
Context-dependent effects of dipeptidyl peptidase 4 inhibitors.

Current opinion in nephrology and hypertension| PubMed ID: 27898522

2017
RACK1 regulates angiotensin II-induced contractions of SHR preglomerular vascular smooth muscle cells.

American journal of physiology. Renal physiology| PubMed ID: 28100502

2017
2017
2017
Adenosine production by brain cells.

Journal of neurochemistry| PubMed ID: 28294336

2017
Suppression of Lymphocyte Functions by Plasma Exosomes Correlates with Disease Activity in Patients with Head and Neck Cancer.

Clinical cancer research : an official journal of the American Association for Cancer Research| PubMed ID: 28400428

2017
2017
2017
2017
2017
2017
2018
2018
2018
2018
2018
2018
2019
2018
2019
2020
2018
2',3'-cGMP exists in vivo and comprises a 2',3'-cGMP-guanosine pathway.

American journal of physiology. Regulatory, integrative and comparative physiology| PubMed ID: 30789788

2019
2019
2019
2020
2020
Estradiol Metabolism: Crossroads in Pulmonary Arterial Hypertension.

International journal of molecular sciences| PubMed ID: 31877978

2019
2020
Adenosine-producing regulatory B cells in head and neck cancer.

Cancer immunology, immunotherapy : CII| PubMed ID: 32146518

2020
Activation of AMP-activated protein kinase during sepsis/inflammation improves survival by preserving cellular metabolic fitness.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology| PubMed ID: 32246808

2020
2020
2020
2020
2020
2020
2020
Adenosine receptors regulate exosome production.

Purinergic signalling| PubMed ID: 32440820

2020
2020
2020
2020
2020
2020
2020
2020
2020
2021
2021
2021
2021