Edwin K. Jackson

Department of Pharmacology and Chemical Biology, University of Pittsburgh

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title Cited by 2	2021

Other Publications

Article	Year
Adenosine-mediated inhibition of the cytotoxic activity and cytokine production by activated natural killer cells. Cancer research\| PubMed ID: 16885379	2006
Sex hormones and hypertension. Cardiovascular research\| PubMed ID: 11861040	2002
A(2B) adenosine receptors stimulate growth of porcine and rat arterial endothelial cells. Hypertension (Dallas, Tex. : 1979)\| PubMed ID: 11882603	2002
Long-term caffeine consumption exacerbates renal failure in obese, diabetic, ZSF1 (fa-fa(cp)) rats. Kidney international\| PubMed ID: 11918750	2002
Catecholamines block 2-hydroxyestradiol-induced antimitogenesis in mesangial cells. Hypertension (Dallas, Tex. : 1979)\| PubMed ID: 11967239	2002
Expression of adenosine receptors in the preglomerular microcirculation. American journal of physiology. Renal physiology\| PubMed ID: 12060585	2002
Administration of adenosine receptor agonists or antagonists after controlled cortical impact in mice: effects on function and histopathology. Brain research\| PubMed ID: 12270497	2002
2-Hydroxyestradiol attenuates renal disease in chronic puromycin aminonucleoside nephropathy. Journal of the American Society of Nephrology : JASN\| PubMed ID: 12397044	2002
alpha 2-Adrenoceptors potentiate angiotensin II- and vasopressin-induced renal vasoconstriction in spontaneously hypertensive rats. The Journal of pharmacology and experimental therapeutics\| PubMed ID: 12606648	2003
Role of EGFR transactivation in angiotensin II signaling to extracellular regulated kinase in preglomerular smooth muscle cells. Hypertension (Dallas, Tex. : 1979)\| PubMed ID: 12623996	2003
Type IV phosphodiesterase inhibition improves cardiac contractility in endotoxemic rats. European journal of pharmacology\| PubMed ID: 12650842	2003
Oviduct cells express the cyclic AMP-adenosine pathway. Biology of reproduction\| PubMed ID: 12724271	2003
Methylation of 2-hydroxyestradiol in isolated organs. Hypertension (Dallas, Tex. : 1979)\| PubMed ID: 12771046	2003
Rat models of the metabolic syndrome. Methods in molecular medicine\| PubMed ID: 12886760	2003
Renal extraction of angiotensin II. The Journal of pharmacology and experimental therapeutics\| PubMed ID: 14534364	2003
Adenosine biosynthesis in the collecting duct. The Journal of pharmacology and experimental therapeutics\| PubMed ID: 14560043	2003
Methoxyestradiols mediate the antimitogenic effects of 17beta-estradiol: direct evidence from catechol-O-methyltransferase-knockout mice. Circulation\| PubMed ID: 14662705	2003
AT2 receptors attenuate AT1 receptor-induced phospholipase D activation in vascular smooth muscle cells. The Journal of pharmacology and experimental therapeutics\| PubMed ID: 14722318	2004
2-hydroxyestradiol is a prodrug of 2-methoxyestradiol. The Journal of pharmacology and experimental therapeutics\| PubMed ID: 14872091	2004
The extracellular cyclic AMP-adenosine pathway in renal physiology. Annual review of physiology\| PubMed ID: 14977414	2004
Vascular endothelial growth factor is increased in cerebrospinal fluid after traumatic brain injury in infants and children. Neurosurgery\| PubMed ID: 15028134	2004
Modulation of cyclic AMP production by signal transduction pathways in preglomerular microvessels and microvascular smooth muscle cells. The Journal of pharmacology and experimental therapeutics\| PubMed ID: 15087474	2004
A gas chromatography/mass spectrometry assay to measure estradiol, catecholestradiols, and methoxyestradiols in plasma. Steroids\| PubMed ID: 15183691	2004
Increased expression of the sodium transporter BSC-1 in spontaneously hypertensive rats. The Journal of pharmacology and experimental therapeutics\| PubMed ID: 15340004	2004
Continuous versus intermittent cerebrospinal fluid drainage after severe traumatic brain injury in children: effect on biochemical markers. Journal of neurotrauma\| PubMed ID: 15453982	2004
Hormone replacement therapy and cardiovascular disease: what went wrong and where do we go from here? Hypertension (Dallas, Tex. : 1979)\| PubMed ID: 15477384	2004
Intraperitoneal administration of adenosine inhibits formation of abdominal adhesions. Diseases of the colon and rectum\| PubMed ID: 15484355	2004
Enhanced activation of RhoA by angiotensin II in SHR preglomerular microvascular smooth muscle cells. Journal of cardiovascular pharmacology\| PubMed ID: 15772513	2005
Vascular consequences of menopause and hormone therapy: importance of timing of treatment and type of estrogen. Cardiovascular research\| PubMed ID: 15820198	2005
Mechanism of the vascular angiotensin II/alpha2-adrenoceptor interaction. The Journal of pharmacology and experimental therapeutics\| PubMed ID: 15901799	2005
Characterization of the effects of adenosine receptor agonists on cerebral blood flow in uninjured and traumatically injured rat brain using continuous arterial spin-labeled magnetic resonan... Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism\| PubMed ID: 15931163	2005
Estradiol metabolites attenuate renal and cardiovascular injury induced by chronic nitric oxide synthase inhibition. Journal of cardiovascular pharmacology\| PubMed ID: 15965351	2005
Adenosine inhibits PDGF-induced growth of human glomerular mesangial cells via A(2B) receptors. Hypertension (Dallas, Tex. : 1979)\| PubMed ID: 16103269	2005
Adenosine A1 receptor knockout mice develop lethal status epilepticus after experimental traumatic brain injury. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism\| PubMed ID: 16121125	2006
Estradiol metabolites attenuate monocrotaline-induced pulmonary hypertension in rats. Journal of cardiovascular pharmacology\| PubMed ID: 16160593	2005
Gs protein-coupled adenosine receptor signaling and lytic function of activated NK cells. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 16177079	2005
Pancreatic polypeptide-fold peptide receptors and angiotensin II-induced renal vasoconstriction. Hypertension (Dallas, Tex. : 1979)\| PubMed ID: 16365188	2006
cAMP-adenosine pathway in the proximal tubule. The Journal of pharmacology and experimental therapeutics\| PubMed ID: 16527902	2006
Role of renal sympathetic nerves in regulating renovascular responses to angiotensin II in spontaneously hypertensive rats. The Journal of pharmacology and experimental therapeutics\| PubMed ID: 16537795	2006
2-Methoxyestradiol mediates the protective effects of estradiol in monocrotaline-induced pulmonary hypertension. Vascular pharmacology\| PubMed ID: 16872912	2006
A2A adenosine receptor protects tumors from antitumor T cells. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 16916931	2006
Conversion of tibolone to 7alpha-methyl-ethinyl estradiol using gas chromatography-mass spectrometry and liquid chromatography-mass spectrometry: interpretation and clinical implications. Menopause (New York, N.Y.)\| PubMed ID: 17006378	2006
The extracellular cAMP-adenosine pathway significantly contributes to the in vivo production of adenosine. The Journal of pharmacology and experimental therapeutics\| PubMed ID: 17028245	2007
2-Methoxyestradiol and 2-ethoxyestradiol retard the progression of renal disease in aged, obese, diabetic ZSF1 rats. Journal of cardiovascular pharmacology\| PubMed ID: 17261964	2007
PPAR alpha agonists improve renal preservation in kidneys subjected to chronic in vitro perfusion: interaction with mannitol. Transplant international : official journal of the European Society for Organ Transplantation\| PubMed ID: 17291221	2007
Characterization of renal ecto-phosphodiesterase. The Journal of pharmacology and experimental therapeutics\| PubMed ID: 17308037	2007
Phospholipase C and Src modulate angiotensin II-induced cyclic AMP production in preglomerular microvascular smooth-muscle cells from spontaneously hypertensive rats. Journal of cardiovascular pharmacology\| PubMed ID: 17312452	2007
The pancreatohepatorenal cAMP-adenosine mechanism. The Journal of pharmacology and experimental therapeutics\| PubMed ID: 17314200	2007
Adenosine-mediated inhibition of cytotoxic activity and cytokine production by IL-2/NKp46-activated NK cells: involvement of protein kinase A isozyme I (PKA I). Immunologic research\| PubMed ID: 17337770	2006
Norepinephrine, via beta-adrenoceptors, regulates bumetanide-sensitive cotransporter type 1 expression in thick ascending limb cells. Hypertension (Dallas, Tex. : 1979)\| PubMed ID: 17438304	2007
Inhibition of cytokine production and cytotoxic activity of human antimelanoma specific CD8+ and CD4+ T lymphocytes by adenosine-protein kinase A type I signaling. Cancer research\| PubMed ID: 17575165	2007
Emergency preservation and resuscitation with profound hypothermia, oxygen, and glucose allows reliable neurological recovery after 3 h of cardiac arrest from rapid exsanguination in dogs. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism\| PubMed ID: 17622254	2008
Increases in cerebrospinal fluid caffeine concentration are associated with favorable outcome after severe traumatic brain injury in humans. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism\| PubMed ID: 17684518	2008
Inhibition of renal dipeptidyl peptidase IV enhances peptide YY1-36-induced potentiation of angiotensin II-mediated renal vasoconstriction in spontaneously hypertensive rats. The Journal of pharmacology and experimental therapeutics\| PubMed ID: 17726157	2007
Cellular distribution of the renal bumetanide-sensitive Na-K-2Cl cotransporter BSC-1 in the inner stripe of the outer medulla during the development of hypertension in the spontaneously hype... Clinical and experimental pharmacology & physiology\| PubMed ID: 17973873	2007
Early renal injury induced by caffeine consumption in obese, diabetic ZSF1 rats. Renal failure\| PubMed ID: 17994459	2007
Importance of tissue perfusion in ST segment elevation myocardial infarction patients undergoing reperfusion strategies: role of adenosine. Clinical cardiology\| PubMed ID: 18000974	2007
Multiplex assessment of cytokine and chemokine levels in cerebrospinal fluid following severe pediatric traumatic brain injury: effects of moderate hypothermia. Journal of neurotrauma\| PubMed ID: 18001201	2007
Effects of dipeptidyl peptidase iv inhibition on arterial blood pressure. Clinical and experimental pharmacology & physiology\| PubMed ID: 18047624	2008
Chronic noradrenaline increases renal expression of NHE-3, NBC-1, BSC-1 and aquaporin-2. Clinical and experimental pharmacology & physiology\| PubMed ID: 18177483	2008
Regulation of renal ectophosphodiesterase by protein kinase C and sodium diet. The Journal of pharmacology and experimental therapeutics\| PubMed ID: 18223197	2008
Alpha2-adrenoceptors enhance angiotensin II-induced renal vasoconstriction: role for NADPH oxidase and RhoA. Hypertension (Dallas, Tex. : 1979)\| PubMed ID: 18250367	2008
Assessment of nerve stimulation-induced release of purines from mouse kidneys by tandem mass spectrometry. The Journal of pharmacology and experimental therapeutics\| PubMed ID: 18322147	2008
2-Ethoxyestradiol is antimitogenic and attenuates monocrotaline-induced pulmonary hypertension and vascular remodeling. Vascular pharmacology\| PubMed ID: 18373958	2008
Sitagliptin augments sympathetic enhancement of the renovascular effects of angiotensin II in genetic hypertension. Hypertension (Dallas, Tex. : 1979)\| PubMed ID: 18443229	2008
Identification and quantification of 2',3'-cAMP release by the kidney. The Journal of pharmacology and experimental therapeutics\| PubMed ID: 19033554	2009
Treating acute "no-reflow" with intracoronary adenosine in 4 patients during percutaneous coronary intervention. Texas Heart Institute journal\| PubMed ID: 19156238	2008
Nonresolving inflammation in gp91phox-/- mice, a model of human chronic granulomatous disease, has lower adenosine and cyclic adenosine 5'-monophosphate. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 19234224	2009
Adenosine deaminase-adenosine pathway in hemolysis-associated pulmonary hypertension. Medical hypotheses\| PubMed ID: 19237250	2009
Regulation of renovascular adenosine 3',5'-cyclic monophosphate in spontaneously hypertensive rats. Hypertension (Dallas, Tex. : 1979)\| PubMed ID: 19528365	2009
2-methoxyestradiol attenuates bleomycin-induced pulmonary hypertension and fibrosis in estrogen-deficient rats. Vascular pharmacology\| PubMed ID: 19540933	2009
Multidrug resistance protein 4 mediates cAMP efflux from rat preglomerular vascular smooth muscle cells. Clinical and experimental pharmacology & physiology\| PubMed ID: 19671067	2010
Potential vascular actions of 2-methoxyestradiol. Trends in endocrinology and metabolism: TEM\| PubMed ID: 19734053	2009
Effects of estradiol metabolites on cAMP production and degradation. Prilozi\| PubMed ID: 19736528	2009
Extracellular 2',3'-cAMP is a source of adenosine. The Journal of biological chemistry\| PubMed ID: 19801686	2009
Increased ectonucleotidase expression and activity in regulatory T cells of patients with head and neck cancer. Clinical cancer research : an official journal of the American Association for Cancer Research\| PubMed ID: 19825957	2009
Generation and accumulation of immunosuppressive adenosine by human CD4+CD25highFOXP3+ regulatory T cells. The Journal of biological chemistry\| PubMed ID: 19858205	2010
Adenosine A1 receptor activation as a brake on the microglial response after experimental traumatic brain injury in mice. Journal of neurotrauma\| PubMed ID: 20121416	2010
Extracellular 3',5'-cAMP-adenosine pathway inhibits glomerular mesangial cell growth. The Journal of pharmacology and experimental therapeutics\| PubMed ID: 20194527	2010
Sitagliptin augments angiotensin II-induced renal vasoconstriction in kidneys from rats with metabolic syndrome. Clinical and experimental pharmacology & physiology\| PubMed ID: 20374254	2010
Extracellular 2,3-cyclic adenosine monophosphate is a potent inhibitor of preglomerular vascular smooth muscle cell and mesangial cell growth [corrected]. Hypertension (Dallas, Tex. : 1979)\| PubMed ID: 20516392	2010
Resveratrol, a red wine constituent, blocks the antimitogenic effects of estradiol on human female coronary artery smooth muscle cells. The Journal of clinical endocrinology and metabolism\| PubMed ID: 20534756	2010
Adenosine and prostaglandin E2 cooperate in the suppression of immune responses mediated by adaptive regulatory T cells. The Journal of biological chemistry\| PubMed ID: 20558731	2010
Estradiol stimulates capillary formation by human endothelial progenitor cells: role of estrogen receptor-{alpha}/{beta}, heme oxygenase 1, and tyrosine kinase. Hypertension\| PubMed ID: 20644008	2010
Synergistic therapeutic effects of 2-methoxyestradiol with either sildenafil or bosentan on amelioration of monocrotaline-induced pulmonary hypertension and vascular remodeling. Journal of cardiovascular pharmacology\| PubMed ID: 20881615	2010
Candidate genes and mechanisms for 2-methoxyestradiol-mediated vasoprotection. Hypertension (Dallas, Tex. : 1979)\| PubMed ID: 20921434	2010
Receptor desensitization and blockade of the suppressive effects of prostaglandin E(2) and adenosine on the cytotoxic activity of human melanoma-infiltrating T lymphocytes. Cancer immunology, immunotherapy : CII\| PubMed ID: 20960188	2011
Regulation of 3',5'-cAMP in preglomerular smooth muscle and endothelial cells from genetically hypertensive rats. Hypertension (Dallas, Tex. : 1979)\| PubMed ID: 20975032	2010
2'-AMP and 3'-AMP inhibit proliferation of preglomerular vascular smooth muscle cells and glomerular mesangial cells via A2B receptors. The Journal of pharmacology and experimental therapeutics\| PubMed ID: 21270135	2011
Blast exposure in rats with body shielding is characterized primarily by diffuse axonal injury. Journal of neurotrauma\| PubMed ID: 21449683	2011
Role of sphingosine-1-phosphate in the renal medulla. American journal of physiology. Renal physiology\| PubMed ID: 21511695	2011
2',3'-cAMP, 3'-AMP, and 2'-AMP inhibit human aortic and coronary vascular smooth muscle cell proliferation via A2B receptors. American journal of physiology. Heart and circulatory physiology\| PubMed ID: 21622827	2011
Extracellular cAMP-adenosine pathways in the mouse kidney. American journal of physiology. Renal physiology\| PubMed ID: 21653635	2011
Expression of the 2',3'-cAMP-adenosine pathway in astrocytes and microglia. Journal of neurochemistry\| PubMed ID: 21777245	2011
Receptor for activated protein kinase C1 regulates cell proliferation by modulating calcium signaling. Hypertension\| PubMed ID: 21844488	2011
The 2',3'-cAMP-adenosine pathway. American journal of physiology. Renal physiology\| PubMed ID: 21937608	2011
Microglial depletion using intrahippocampal injection of liposome-encapsulated clodronate in prolonged hypothermic cardiac arrest in rats. Resuscitation\| PubMed ID: 21970817	2012
Endogenous adenosine contributes to renal sympathetic neurotransmission via postjunctional A1 receptor-mediated coincident signaling. American journal of physiology. Renal physiology\| PubMed ID: 22114202	2012
Hypertension, tachycardia, and reversible cardiomyopathy temporally associated with milnacipran use. Texas Heart Institute journal\| PubMed ID: 22199446	2011
Increased adenosine concentration in bronchoalveolar lavage fluid of horses with lower airway inflammation. Veterinary journal (London, England : 1997)\| PubMed ID: 22206730	2011
The brain in vivo expresses the 2',3'-cAMP-adenosine pathway. Journal of neurochemistry\| PubMed ID: 22360621	2012
Modulation of bladder function by luminal adenosine turnover and A1 receptor activation. American journal of physiology. Renal physiology\| PubMed ID: 22552934	2012
Extracellular 2',3'-cAMP and 3',5'-cAMP stimulate proliferation of preglomerular vascular endothelial cells and renal epithelial cells. American journal of physiology. Renal physiology\| PubMed ID: 22791337	2012
Dipeptidyl peptidase IV regulates proliferation of preglomerular vascular smooth muscle and mesangial cells. Hypertension (Dallas, Tex. : 1979)\| PubMed ID: 22802229	2012
Role of A1 receptors in renal sympathetic neurotransmission in the mouse kidney. American journal of physiology. Renal physiology\| PubMed ID: 22874760	2012
CD26 expression and adenosine deaminase activity in regulatory T cells (Treg) and CD4(+) T effector cells in patients with head and neck squamous cell carcinoma. Oncoimmunology\| PubMed ID: 22934258	2012
Extracellular 2',3'-cAMP-adenosine pathway in proximal tubular, thick ascending limb, and collecting duct epithelial cells. American journal of physiology. Renal physiology\| PubMed ID: 23077101	2013
Extracellular guanosine regulates extracellular adenosine levels. American journal of physiology. Cell physiology\| PubMed ID: 23242185	2013
Role of RACK1 in the differential proliferative effects of neuropeptide Y(1-36) and peptide YY(1-36) in SHR vs. WKY preglomerular vascular smooth muscle cells. American journal of physiology. Renal physiology\| PubMed ID: 23303411	2013
Screening of biochemical and molecular mechanisms of secondary injury and repair in the brain after experimental blast-induced traumatic brain injury in rats. Journal of neurotrauma\| PubMed ID: 23496248	2013
Adenosine production by human B cells and B cell-mediated suppression of activated T cells. Blood\| PubMed ID: 23678003	2013
In vivo cardiovascular pharmacology of 2',3'-cAMP, 2'-AMP, and 3'-AMP in the rat. The Journal of pharmacology and experimental therapeutics\| PubMed ID: 23759508	2013
CD39 expression by hepatic myeloid dendritic cells attenuates inflammation in liver transplant ischemia-reperfusion injury in mice. Hepatology (Baltimore, Md.)\| PubMed ID: 23813862	2013
Adenosine and prostaglandin e2 production by human inducible regulatory T cells in health and disease. Frontiers in immunology\| PubMed ID: 23898333	2013
Role of CNPase in the oligodendrocytic extracellular 2',3'-cAMP-adenosine pathway. Glia\| PubMed ID: 23922219	2013
Regulation of Cell Proliferation by the Guanosine-Adenosine Mechanism: Role of Adenosine Receptors. Physiological reports\| PubMed ID: 23956837	2013
The β-blocker Nebivolol Is a GRK/β-arrestin biased agonist. PloS one\| PubMed ID: 23977191	2013
CD4⁺CD73⁺ T cells are associated with lower T-cell activation and C reactive protein levels and are depleted in HIV-1 infection regardless of viral suppression. AIDS (London, England)\| PubMed ID: 24005375	2013
Pharmacological inhibition of pleckstrin homology domain leucine-rich repeat protein phosphatase is neuroprotective: differential effects on astrocytes. The Journal of pharmacology and experimental therapeutics\| PubMed ID: 24023368	2013
Role of CD73 in Renal Sympathetic Neurotransmission in the Mouse Kidney. Physiological reports\| PubMed ID: 24066228	2013
A novel adenosine precursor 2',3'-cyclic adenosine monophosphate inhibits formation of post-surgical adhesions. Digestive diseases and sciences\| PubMed ID: 24711075	2014
Hemorrhagic shock shifts the serum cytokine profile from pro- to anti-inflammatory after experimental traumatic brain injury in mice. Journal of neurotrauma\| PubMed ID: 24773520	2014
Role of 2',3'-cyclic nucleotide 3'-phosphodiesterase in the renal 2',3'-cAMP-adenosine pathway. American journal of physiology. Renal physiology\| PubMed ID: 24808540	2014
Guanosine regulates adenosine levels in the kidney. Physiological reports\| PubMed ID: 24872359	2014
Interactive roles of CD73 and tissue nonspecific alkaline phosphatase in the renal vascular metabolism of 5'-AMP. American journal of physiology. Renal physiology\| PubMed ID: 24990899	2014
The guanosine-adenosine interaction exists in vivo. The Journal of pharmacology and experimental therapeutics\| PubMed ID: 25002416	2014
Angiotensin II type 2 receptor regulates ROMK-like K⁺ channel activity in the renal cortical collecting duct during high dietary K⁺ adaptation. American journal of physiology. Renal physiology\| PubMed ID: 25100281	2014
Systemic oxygenation weakens the hypoxia and hypoxia inducible factor 1α-dependent and extracellular adenosine-mediated tumor protection. Journal of molecular medicine (Berlin, Germany)\| PubMed ID: 25120128	2014
Prevention of skin carcinogenesis by the β-blocker carvedilol. Cancer prevention research (Philadelphia, Pa.)\| PubMed ID: 25367979	2015
Effect of dipeptidyl peptidase 4 inhibition on arterial blood pressure is context dependent. Hypertension (Dallas, Tex. : 1979)\| PubMed ID: 25368027	2015
2',3'-cAMP, 3'-AMP, 2'-AMP and adenosine inhibit TNF-α and CXCL10 production from activated primary murine microglia via A2A receptors. Brain research\| PubMed ID: 25451117	2015
Blockade of ENaCs by amiloride induces c-Fos activation of the area postrema. Brain research\| PubMed ID: 25557402	2015
The nuclear splicing factor RNA binding motif 5 promotes caspase activation in human neuronal cells, and increases after traumatic brain injury in mice. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism\| PubMed ID: 25586139	2015
Emerging therapies in traumatic brain injury. Seminars in neurology\| PubMed ID: 25714870	2015
Immunological mechanisms of the antitumor effects of supplemental oxygenation. Science translational medicine\| PubMed ID: 25739764	2015
Detection of PHLPP1α/β in human and mouse brain by different anti-PHLPP1 antibodies. Scientific reports\| PubMed ID: 25827478	2015
Schwann Cells Metabolize Extracellular 2',3'-cAMP to 2'-AMP. The Journal of pharmacology and experimental therapeutics\| PubMed ID: 25998049	2015
Structure Guided Chemical Modifications of Propylthiouracil Reveal Novel Small Molecule Inhibitors of Cytochrome b5 Reductase 3 That Increase Nitric Oxide Bioavailability. The Journal of biological chemistry\| PubMed ID: 26001785	2015
Genetic variation in the adenosine regulatory cycle is associated with posttraumatic epilepsy development. Epilepsia\| PubMed ID: 26040919	2015
Critical Role for the Adenosine Pathway in Controlling Simian Immunodeficiency Virus-Related Immune Activation and Inflammation in Gut Mucosal Tissues. Journal of virology\| PubMed ID: 26178986	2015
Cold stress protein RBM3 responds to temperature change in an ultra-sensitive manner in young neurons. Neuroscience\| PubMed ID: 26265550	2015
NPY1-36 and PYY1-36 activate cardiac fibroblasts: an effect enhanced by genetic hypertension and inhibition of dipeptidyl peptidase 4. American journal of physiology. Heart and circulatory physiology\| PubMed ID: 26371160	2015
Adenosine Attenuates Human Coronary Artery Smooth Muscle Cell Proliferation by Inhibiting Multiple Signaling Pathways That Converge on Cyclin D. Hypertension (Dallas, Tex. : 1979)\| PubMed ID: 26416848	2015
2-Methoxyestradiol blocks the RhoA/ROCK1 pathway in human aortic smooth muscle cells. American journal of physiology. Endocrinology and metabolism\| PubMed ID: 26487003	2015
Renal 2',3'-Cyclic Nucleotide 3'-Phosphodiesterase Is an Important Determinant of AKI Severity after Ischemia-Reperfusion. Journal of the American Society of Nephrology : JASN\| PubMed ID: 26574047	2016
Dual A1/A2B Receptor Blockade Improves Cardiac and Renal Outcomes in a Rat Model of Heart Failure with Preserved Ejection Fraction. The Journal of pharmacology and experimental therapeutics\| PubMed ID: 26585572	2016
Discovery and Roles of 2',3'-cAMP in Biological Systems. Handbook of experimental pharmacology\| PubMed ID: 26721674	2017
2-Methoxyestradiol, an endogenous 17β-estradiol metabolite, inhibits microglial proliferation and activation via an estrogen receptor-independent mechanism. American journal of physiology. Endocrinology and metabolism\| PubMed ID: 26732685	2016
Purines: forgotten mediators in traumatic brain injury. Journal of neurochemistry\| PubMed ID: 26809224	2016
Adenosine metabolism of human mesenchymal stromal cells isolated from patients with head and neck squamous cell carcinoma. Immunobiology\| PubMed ID: 26898925	2017
Estrogens in Men: Another Layer of Complexity of Estradiol Metabolism in Pulmonary Hypertension. American journal of respiratory and critical care medicine\| PubMed ID: 27174480	2016
8-Aminoguanosine and 8-Aminoguanine Exert Diuretic, Natriuretic, Glucosuric, and Antihypertensive Activity. The Journal of pharmacology and experimental therapeutics\| PubMed ID: 27679494	2016
The Kallikrein-Kinin System: A Novel Mediator of IL-17-Driven Anti-Candida Immunity in the Kidney. PLoS pathogens\| PubMed ID: 27814401	2016
Context-dependent effects of dipeptidyl peptidase 4 inhibitors. Current opinion in nephrology and hypertension\| PubMed ID: 27898522	2017
RACK1 regulates angiotensin II-induced contractions of SHR preglomerular vascular smooth muscle cells. American journal of physiology. Renal physiology\| PubMed ID: 28100502	2017
Alkaline Phosphatase Inhibitors Attenuate Renovascular Responses to Norepinephrine. Hypertension (Dallas, Tex. : 1979)\| PubMed ID: 28137984	2017
Editorial for "Hypertension's 3 Dilemmas & 3 Solutions: Pharmacology of the Kidney in Hypertension". Journal of cardiovascular pharmacology\| PubMed ID: 28267686	2017
Adenosine production by brain cells. Journal of neurochemistry\| PubMed ID: 28294336	2017
Suppression of Lymphocyte Functions by Plasma Exosomes Correlates with Disease Activity in Patients with Head and Neck Cancer. Clinical cancer research : an official journal of the American Association for Cancer Research\| PubMed ID: 28400428	2017
Proximal tubule apical endocytosis is modulated by fluid shear stress via an mTOR-dependent pathway. Molecular biology of the cell\| PubMed ID: 28720662	2017
Human tumor-derived exosomes (TEX) regulate Treg functions via cell surface signaling rather than uptake mechanisms. Oncoimmunology\| PubMed ID: 28919985	2017
8-Aminoguanosine Exerts Diuretic, Natriuretic, and Glucosuric Activity via Conversion to 8-Aminoguanine, Yet Has Direct Antikaliuretic Effects. The Journal of pharmacology and experimental therapeutics\| PubMed ID: 28928119	2017
Circulating exosomes carrying an immunosuppressive cargo interfere with cellular immunotherapy in acute myeloid leukemia. Scientific reports\| PubMed ID: 29089618	2017
SDF-1α (Stromal Cell-Derived Factor 1α) Induces Cardiac Fibroblasts, Renal Microvascular Smooth Muscle Cells, and Glomerular Mesangial Cells to Proliferate, Cause Hypertrophy, and Produce Co... Journal of the American Heart Association\| PubMed ID: 29114002	2017
BrainPhys® increases neurofilament levels in CNS cultures, and facilitates investigation of axonal damage after a mechanical stretch-injury in vitro. Experimental neurology\| PubMed ID: 29199132	2018
The influence of chemotherapy on adenosine-producing B cells in patients with head and neck squamous cell carcinoma. Oncotarget\| PubMed ID: 29464038	2018
Captopril Attenuates Cardiovascular and Renal Disease in a Rat Model of Heart Failure With Preserved Ejection Fraction. Journal of cardiovascular pharmacology\| PubMed ID: 29620605	2018
Acute Physiology and Neurologic Outcomes after Brain Injury in SCOP/PHLPP1 KO Mice. Scientific reports\| PubMed ID: 29739983	2018
Adenosine Receptors Influence Hypertension in Dahl Salt-Sensitive Rats: Dependence on Receptor Subtype, Salt Diet, and Sex. Hypertension (Dallas, Tex. : 1979)\| PubMed ID: 29941515	2018
Experimental intravascular hemolysis induces hemodynamic and pathological pulmonary hypertension: association with accelerated purine metabolism. Pulmonary circulation\| PubMed ID: 30003836	2018
Aging increases the expression of vasopressin receptors in both the kidney and urinary bladder. Neurourology and urodynamics\| PubMed ID: 30311671	2019
Extracellular Ubiquitin(1-76) and Ubiquitin(1-74) Regulate Cardiac Fibroblast Proliferation. Hypertension (Dallas, Tex. : 1979)\| PubMed ID: 30354710	2018
Oxidative stress induces release of 2'-AMP from microglia. Brain research\| PubMed ID: 30395838	2019
Paths to Successful Translation of New Therapies for Severe Traumatic Brain Injury in the Golden Age of Traumatic Brain Injury Research: A Pittsburgh Vision. Journal of neurotrauma\| PubMed ID: 30520681	2020
8-Aminoguanine Induces Diuresis, Natriuresis, and Glucosuria by Inhibiting Purine Nucleoside Phosphorylase and Reduces Potassium Excretion by Inhibiting Rac1. Journal of the American Heart Association\| PubMed ID: 30608204	2018
2',3'-cGMP exists in vivo and comprises a 2',3'-cGMP-guanosine pathway. American journal of physiology. Regulatory, integrative and comparative physiology\| PubMed ID: 30789788	2019
2-Methoxyestradiol Attenuates Angiotensin II-Induced Hypertension, Cardiovascular Remodeling, and Renal Injury. Journal of cardiovascular pharmacology\| PubMed ID: 30839510	2019
Mechanism of 17β-estradiol stimulated integration of human mesenchymal stem cells in heart tissue. Journal of molecular and cellular cardiology\| PubMed ID: 31201797	2019
A Randomized, Placebo-Controlled, Pilot Clinical Trial of Dipyridamole to Decrease Human Immunodeficiency Virus-Associated Chronic Inflammation. The Journal of infectious diseases\| PubMed ID: 31282542	2020
Adenosine, Via A Receptors, Inhibits Human (P-SMC) Progenitor Smooth Muscle Cell Growth. Hypertension (Dallas, Tex. : 1979)\| PubMed ID: 31786976	2020
Estradiol Metabolism: Crossroads in Pulmonary Arterial Hypertension. International journal of molecular sciences\| PubMed ID: 31877978	2019
DPP4 Inhibition, NPY, PYY, SDF-1, and a Hypertensive Genetic Background Conspire to Augment Cell Proliferation and Collagen Production: Effects That Are Abolished by Low Concentrations of 2-... The Journal of pharmacology and experimental therapeutics\| PubMed ID: 32015161	2020
Adenosine-producing regulatory B cells in head and neck cancer. Cancer immunology, immunotherapy : CII\| PubMed ID: 32146518	2020
Activation of AMP-activated protein kinase during sepsis/inflammation improves survival by preserving cellular metabolic fitness. FASEB journal : official publication of the Federation of American Societies for Experimental Biology\| PubMed ID: 32246808	2020
Intercalated cell BKα subunit is required for flow-induced K+ secretion. JCI insight\| PubMed ID: 32255763	2020
Simultaneous Inhibition of Glycolysis and Oxidative Phosphorylation Triggers a Multi-Fold Increase in Secretion of Exosomes: Possible Role of 2'3'-cAMP. Scientific reports\| PubMed ID: 32332778	2020
Identification of Novel Targets of RBM5 in the Healthy and Injured Brain. Neuroscience\| PubMed ID: 32335213	2020
Characterization of the N-etheno-bridge method to assess extracellular metabolism of adenine nucleotides: detection of a possible role for purine nucleoside phosphorylase in adenosine metabo... Purinergic signalling\| PubMed ID: 32367441	2020
Tumor-derived exosomes promote angiogenesis via adenosine A receptor signaling. Angiogenesis\| PubMed ID: 32419057	2020
-Adrenoceptors: Challenges and Opportunities-Enlightenment from the Kidney. Cardiovascular therapeutics\| PubMed ID: 32426035	2020
Adenosine receptors regulate exosome production. Purinergic signalling\| PubMed ID: 32440820	2020
Role of exosome-associated adenosine in promoting angiogenesis. Vessel plus\| PubMed ID: 32490359	2020
Purine Metabolites in Tumor-Derived Exosomes May Facilitate Immune Escape of Head and Neck Squamous Cell Carcinoma. Cancers\| PubMed ID: 32560461	2020
Immune Suppressive Effects of Plasma-Derived Exosome Populations in Head and Neck Cancer. Cancers\| PubMed ID: 32708274	2020
Author Correction: Simultaneous Inhibition of Glycolysis and Oxidative Phosphorylation Triggers a Multi-Fold Increase in Secretion of Exosomes: Possible Role of 2',3'-cAMP. Scientific reports\| PubMed ID: 32807847	2020
Alkaline Phosphatase Activity Is a Key Determinant of Vascular Responsiveness to Norepinephrine. Hypertension (Dallas, Tex. : 1979)\| PubMed ID: 32829665	2020
Purine nucleoside phosphorylase inhibition ameliorates age-associated lower urinary tract dysfunctions. JCI insight\| PubMed ID: 32910805	2020
A uro-protective agent with restorative actions on urethral and striated muscle morphology. World journal of urology\| PubMed ID: 33078215	2020
Brief Report: Dipyridamole Decreases Gut Mucosal Regulatory T-Cell Frequencies Among People With HIV on Antiretroviral Therapy. Journal of acquired immune deficiency syndromes (1999)\| PubMed ID: 33177477	2020
Novel Guidewire Design and Coating for Continuous Delivery of Adenosine During Interventional Procedures. Journal of the American Heart Association\| PubMed ID: 33496190	2021
Long-Term Dipeptidyl Peptidase 4 Inhibition Worsens Hypertension and Renal and Cardiac Abnormalities in Obese Spontaneously Hypertensive Heart Failure Rats. Journal of the American Heart Association\| PubMed ID: 33682436	2021
Angiotensin II augments renal vascular smooth muscle soluble GC expression via an AT receptor-forkhead box subclass O transcription factor signalling axis. British journal of pharmacology\| PubMed ID: 33963547	2021
Modulation of Cyclic AMP Levels in Fallopian Tube Cells by Natural and Environmental Estrogens. Cells\| PubMed ID: 34069403	2021