Paul S. Freemont

Centre for Synthetic Biology and Innovation, South Kensington Campus

Affiliated withSouth Kensington Campus Imperial College London Imperial College London; Hammersmith Campus

Research Area

Biography

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title Cited by 9	2021

Other Publications

Article	Year
Synthetic biology industry: data-driven design is creating new opportunities in biotechnology. Emerging topics in life sciences\| PubMed ID: 33523172	2019
Bacillus subtilis YngB contributes to wall teichoic acid glucosylation and glycolipid formation during anaerobic growth. The Journal of biological chemistry\| PubMed ID: 33556370	2021
Motions and negative cooperativity between p97 domains revealed by cryo-electron microscopy and quantised elastic deformational model. Journal of molecular biology\| PubMed ID: 12634057	2003
Structural basis of the interaction between the AAA ATPase p97/VCP and its adaptor protein p47. The EMBO journal\| PubMed ID: 14988733	2004
Conformational changes in the AAA ATPase p97-p47 adaptor complex. The EMBO journal\| PubMed ID: 16601695	2006
Cd36, a class B scavenger receptor, functions as a monomer to bind acetylated and oxidized low-density lipoproteins. Protein science : a publication of the Protein Society\| PubMed ID: 17905828	2007
AAA proteins and the life process. Biochemical Society transactions\| PubMed ID: 18208386	2008
Structure-based mechanism of lipoteichoic acid synthesis by Staphylococcus aureus LtaS. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 19168632	2009
Specialization of an Exonuclease III family enzyme in the repair of 3' DNA lesions during base excision repair in the human pathogen Neisseria meningitidis. Nucleic acids research\| PubMed ID: 22067446	2012
Structural basis for the recognition and cleavage of abasic DNA in Neisseria meningitidis. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 23035246	2012
Validation of an entirely in vitro approach for rapid prototyping of DNA regulatory elements for synthetic biology. Nucleic acids research\| PubMed ID: 23371936	2013
The p97-FAF1 protein complex reveals a common mode of p97 adaptor binding. The Journal of biological chemistry\| PubMed ID: 24619421	2014
Structural and mechanistic insight into the Listeria monocytogenes two-enzyme lipoteichoic acid synthesis system. The Journal of biological chemistry\| PubMed ID: 25128528	2014
Coevolution of the ATPase ClpV, the sheath proteins TssB and TssC, and the accessory protein TagJ/HsiE1 distinguishes type VI secretion classes. The Journal of biological chemistry\| PubMed ID: 25305017	2014
Complex structure and biochemical characterization of the Staphylococcus aureus cyclic diadenylate monophosphate (c-di-AMP)-binding protein PstA, the founding member of a new signal transduc... The Journal of biological chemistry\| PubMed ID: 25505271	2015
New quantitative approaches reveal the spatial preference of nuclear compartments in mammalian fibroblasts. Journal of the Royal Society, Interface\| PubMed ID: 25631564	2015
Delineation of metabolic gene clusters in plant genomes by chromatin signatures. Nucleic acids research\| PubMed ID: 26895889	2016
EcoFlex: A Multifunctional MoClo Kit for E. coli Synthetic Biology. ACS synthetic biology\| PubMed ID: 27096716	2016
TssA forms a gp6-like ring attached to the type VI secretion sheath. The EMBO journal\| PubMed ID: 27288401	2016
Development of a Bacillus subtilis cell-free transcription-translation system for prototyping regulatory elements. Metabolic engineering\| PubMed ID: 27697563	2016
Computational protein design with backbone plasticity. Biochemical Society transactions\| PubMed ID: 27911735	2016
Inhibitor Selectivity for Cyclin-Dependent Kinase 7: A Structural, Thermodynamic, and Modelling Study. ChemMedChem\| PubMed ID: 28125165	2017
Streptomyces venezuelae TX-TL - a next generation cell-free synthetic biology tool. Biotechnology journal\| PubMed ID: 28139884	2017
With all due respect to Maholo, lab automation isn't anthropomorphic. Nature biotechnology\| PubMed ID: 28398331	2017
Cell-free synthetic biology for prototype engineering. Biochemical Society transactions\| PubMed ID: 28620040	2017
The AAA+ ATPase p97, a cellular multitool. The Biochemical journal\| PubMed ID: 28819009	2017
Atomic Structure of Type VI Contractile Sheath from Pseudomonas aeruginosa. Structure (London, England : 1993)\| PubMed ID: 29307484	2018
Rapid acquisition and model-based analysis of cell-free transcription-translation reactions from nonmodel bacteria. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 29666238	2018
EcoFlex: A Multifunctional MoClo Kit for E. coli Synthetic Biology. Methods in molecular biology (Clifton, N.J.)\| PubMed ID: 29754244	2018
Building a global alliance of biofoundries. Nature communications\| PubMed ID: 31068573	2019
Author Correction: Building a global alliance of biofoundries. Nature communications\| PubMed ID: 31296848	2019
A Biosynthetic Platform for Antimalarial Drug Discovery. Antimicrobial agents and chemotherapy\| PubMed ID: 32152076	2020
A role for Biofoundries in rapid development and validation of automated SARS-CoV-2 clinical diagnostics. Nature communications\| PubMed ID: 32900994	2020
Author Correction: A role for Biofoundries in rapid development and validation of automated SARS-CoV-2 clinical diagnostics. Nature communications\| PubMed ID: 32943631	2020
Combinatorial metabolic pathway assembly approaches and toolkits for modular assembly. Metabolic engineering\| PubMed ID: 33301873	2021
A Cell-Free Toolkit for Synthetic Biology. ACS synthetic biology\| PubMed ID: 33497199	2021
Refactoring of a synthetic raspberry ketone pathway with EcoFlex. Microbial cell factories\| PubMed ID: 34112158	2021
Correction to: Refactoring of a synthetic raspberry ketone pathway with EcoFlex. Microbial cell factories\| PubMed ID: 34407814	2021