Mark A. Frye

Department of Physiological Science, University of California, Los Angeles

Affiliated withUniversity of California, Los Angeles

Research Area

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JoVE Journal Publications

ArticleTotal : 2	Year
Publication title Cited by 32	2008
Publication title Cited by 8	2009

Other Publications

Article	Year
Clinical predictors of response to lamotrigine and gabapentin monotherapy in refractory affective disorders. Biological psychiatry\| PubMed ID: 11839368	2002
Principal components of the Beck Depression Inventory and regional cerebral metabolism in unipolar and bipolar depression. Biological psychiatry\| PubMed ID: 11904133	2002
Correlates of overweight and obesity in 644 patients with bipolar disorder. The Journal of clinical psychiatry\| PubMed ID: 11926719	2002
Early physical and sexual abuse associated with an adverse course of bipolar illness. Biological psychiatry\| PubMed ID: 11958779	2002
High rate of autoimmune thyroiditis in bipolar disorder: lack of association with lithium exposure. Biological psychiatry\| PubMed ID: 11958781	2002
Mania and attention deficit hyperactivity disorder in a prepubertal child: diagnostic and treatment challenges. The American journal of psychiatry\| PubMed ID: 12042177	2002
Synaptic, intracellular, and neuroprotective mechanisms of anticonvulsants: are they relevant for the treatment and course of bipolar disorders? Journal of affective disorders\| PubMed ID: 12103447	2002
Subsyndromal depression is associated with functional impairment in patients with bipolar disorder. The Journal of clinical psychiatry\| PubMed ID: 12363122	2002
Rash in multicenter trials of lamotrigine in mood disorders: clinical relevance and management. The Journal of clinical psychiatry\| PubMed ID: 12444815	2002
Tiagabine in treatment refractory bipolar disorder: a clinical case series. Bipolar disorders\| PubMed ID: 12479659	2002
Validity of the mood disorder questionnaire: a general population study. The American journal of psychiatry\| PubMed ID: 12505821	2003
Acute antimanic efficacy and safety of oxcarbazepine in an open trial with an on-off-on design. Bipolar disorders\| PubMed ID: 12519102	2002
Low CSF somatostatin associated with response to nimodipine in patents with affective illness. Biological psychiatry\| PubMed ID: 12547475	2003
Odor localization requires visual feedback during free flight in Drosophila melanogaster. The Journal of experimental biology\| PubMed ID: 12547939	2003
Screening for bipolar disorder in the community. The Journal of clinical psychiatry\| PubMed ID: 12590624	2003
Treating acute mania. The Journal of family practice\| PubMed ID: 12676078	2003
Acceleration and augmentation strategies for treating bipolar depression. Biological psychiatry\| PubMed ID: 12706955	2003
Impact of bipolar disorder on a U.S. community sample. The Journal of clinical psychiatry\| PubMed ID: 12716245	2003
Gender differences in prevalence, risk, and clinical correlates of alcoholism comorbidity in bipolar disorder. The American journal of psychiatry\| PubMed ID: 12727691	2003
Factors associated with suicide attempts in 648 patients with bipolar disorder in the Stanley Foundation Bipolar Network. The Journal of clinical psychiatry\| PubMed ID: 12755652	2003
A signature of salience in the Drosophila brain. Nature neuroscience\| PubMed ID: 12771957	2003
Morbidity in 258 bipolar outpatients followed for 1 year with daily prospective ratings on the NIMH life chart method. The Journal of clinical psychiatry\| PubMed ID: 12823083	2003
Impact of antidepressant discontinuation after acute bipolar depression remission on rates of depressive relapse at 1-year follow-up. The American journal of psychiatry\| PubMed ID: 12832239	2003
Psychosis in bipolar disorder: phenomenology and impact on morbidity and course of illness. Comprehensive psychiatry\| PubMed ID: 12923703	2003
An overview of recent findings of the Stanley Foundation Bipolar Network (Part I). Bipolar disorders\| PubMed ID: 14525551	2003
A re-evaluation of the role of antidepressants in the treatment of bipolar depression: data from the Stanley Foundation Bipolar Network. Bipolar disorders\| PubMed ID: 14636363	2003
Spatial organization of visuomotor reflexes in Drosophila. The Journal of experimental biology\| PubMed ID: 14638838	2004
Motor output reflects the linear superposition of visual and olfactory inputs in Drosophila. The Journal of experimental biology\| PubMed ID: 14638839	2004
Clinical and legal correlates of inmates with bipolar disorder at time of criminal arrest. The Journal of clinical psychiatry\| PubMed ID: 15003073	2004
Unmet needs in bipolar depression. Depression and anxiety\| PubMed ID: 15274168	2004
Correlates of 1-year prospective outcome in bipolar disorder: results from the Stanley Foundation Bipolar Network. The American journal of psychiatry\| PubMed ID: 15285972	2004
Chart review of the impact of attention-deficit/hyperactivity disorder comorbidity on response to lithium or divalproex sodium in adolescent mania. The Journal of clinical psychiatry\| PubMed ID: 15323589	2004
Peripheral thyroid hormones and response to selective serotonin reuptake inhibitors. Journal of psychiatry & neuroscience : JPN\| PubMed ID: 15486607	2004
Impact of depressive symptoms compared with manic symptoms in bipolar disorder: results of a U.S. community-based sample. The Journal of clinical psychiatry\| PubMed ID: 15554762	2004
Closing the loop between neurobiology and flight behavior in Drosophila. Current opinion in neurobiology\| PubMed ID: 15582376	2004
Preliminary observations on the effectiveness of levetiracetam in the open adjunctive treatment of refractory bipolar disorder. The Journal of clinical psychiatry\| PubMed ID: 15766304	2005
Open-label adjunctive zonisamide in the treatment of bipolar disorders: a prospective trial. The Journal of clinical psychiatry\| PubMed ID: 15889949	2005
Reproductive function and risk for PCOS in women treated for bipolar disorder. Bipolar disorders\| PubMed ID: 15898962	2005
Comparison of rapid-cycling and non-rapid-cycling bipolar disorder based on prospective mood ratings in 539 outpatients. The American journal of psychiatry\| PubMed ID: 15994709	2005
Relationship between criminal arrest and community treatment history among patients with bipolar disorder. Psychiatric services (Washington, D.C.)\| PubMed ID: 16020818	2005
Patterns of alcohol consumption in bipolar patients comorbid for alcohol abuse or dependence. Bipolar disorders\| PubMed ID: 16026491	2005
Longitudinal evaluation of reproductive function in women treated for bipolar disorder. Journal of affective disorders\| PubMed ID: 16171873	2005
Mixed hypomania in 908 patients with bipolar disorder evaluated prospectively in the Stanley Foundation Bipolar Treatment Network: a sex-specific phenomenon. Archives of general psychiatry\| PubMed ID: 16203954	2005
Clinical and legal characteristics of inmates with bipolar disorder. Current psychiatry reports\| PubMed ID: 16318827	2005
Use of health care services among persons who screen positive for bipolar disorder. Psychiatric services (Washington, D.C.)\| PubMed ID: 16339614	2005
Risk of switch in mood polarity to hypomania or mania in patients with bipolar depression during acute and continuation trials of venlafaxine, sertraline, and bupropion as adjuncts to mood s... The American journal of psychiatry\| PubMed ID: 16449476	2006
Lower switch rate in depressed patients with bipolar II than bipolar I disorder treated adjunctively with second-generation antidepressants. The American journal of psychiatry\| PubMed ID: 16449487	2006
Low cerebrospinal fluid glutamate and glycine in refractory affective disorder. Biological psychiatry\| PubMed ID: 16735030	2007
Double-blind, randomized, placebo-controlled trials of ethyl-eicosapentanoate in the treatment of bipolar depression and rapid cycling bipolar disorder. Biological psychiatry\| PubMed ID: 16814257	2006
Discharge against medical advice from inpatient psychiatric treatment: a literature review. Psychiatric services (Washington, D.C.)\| PubMed ID: 16870972	2006
Healthcare resource utilization in bipolar depression compared with unipolar depression: results of a United States population-based study. CNS spectrums\| PubMed ID: 16946695	2006
Subsyndromal depressive symptoms are associated with functional impairment in patients with bipolar disorder: results of a large, multisite study. The Journal of clinical psychiatry\| PubMed ID: 17107246	2006
Free T4 index and clinical outcome in patients with depression. Journal of affective disorders\| PubMed ID: 17123630	2007
Bipolar disorder and comorbid alcoholism: prevalence rate and treatment considerations. Bipolar disorders\| PubMed ID: 17156154	2006
New findings from the Bipolar Collaborative Network: clinical implications for therapeutics. Current psychiatry reports\| PubMed ID: 17162830	2006
Incidence and time course of subsyndromal symptoms in patients with bipolar I disorder: an evaluation of 2 placebo-controlled maintenance trials. The Journal of clinical psychiatry\| PubMed ID: 17196051	2006
Open-label aripiprazole in the treatment of acute bipolar depression: a prospective pilot trial. Journal of affective disorders\| PubMed ID: 17229469	2007
Alcoholism and anxiety in bipolar illness: differential lifetime anxiety comorbidity in bipolar I women with and without alcoholism. Journal of affective disorders\| PubMed ID: 17254638	2007
Behavioral neurobiology: a vibrating gyroscope controls fly steering maneuvers. Current biology : CB\| PubMed ID: 17307048	2007
Reduced concentrations of N-acetylaspartate (NAA) and the NAA-creatine ratio in the basal ganglia in bipolar disorder: a study using 3-Tesla proton magnetic resonance spectroscopy. Psychiatry research\| PubMed ID: 17346949	2007
Predictors of bipolar disorder risk among patients currently treated for major depression. MedGenMed : Medscape general medicine\| PubMed ID: 17406171	2006
Free-flight odor tracking in Drosophila is consistent with an optimal intermittent scale-free search. PloS one\| PubMed ID: 17406678	2007
Increased anterior cingulate/medial prefrontal cortical glutamate and creatine in bipolar depression. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology\| PubMed ID: 17429412	2007
The poor prognosis of childhood-onset bipolar disorder. The Journal of pediatrics\| PubMed ID: 17452221	2007
Six-month prospective life charting of mood symptoms with lamotrigine monotherapy versus placebo in rapid cycling bipolar disorder. Biological psychiatry\| PubMed ID: 17543894	2008
A 24-week, randomized, controlled trial of adjunctive sibutramine versus topiramate in the treatment of weight gain in overweight or obese patients with bipolar disorders. Bipolar disorders\| PubMed ID: 17547588	2007
Lack of mania prophylaxis associated with lamotrigine monotherapy in manic-predominant bipolar I disorder. The Journal of clinical psychiatry\| PubMed ID: 17592931	2007
Modal subcomponents of metabolic syndrome in patients with bipolar disorder. Journal of affective disorders\| PubMed ID: 17628693	2008
A placebo-controlled evaluation of adjunctive modafinil in the treatment of bipolar depression. The American journal of psychiatry\| PubMed ID: 17671288	2007
Three times more days depressed than manic or hypomanic in both bipolar I and bipolar II disorder. Bipolar disorders\| PubMed ID: 17680925	2007
Comorbid substance use disorder in women with bipolar disorder associated with criminal arrest. Bipolar disorders\| PubMed ID: 17680926	2007
The spatial, temporal and contrast properties of expansion and rotation flight optomotor responses in Drosophila. The Journal of experimental biology\| PubMed ID: 17766299	2007
Quetiapine for the continuation treatment of bipolar depression: naturalistic prospective case series from the Stanley Bipolar Treatment Network. International clinical psychopharmacology\| PubMed ID: 17917557	2007
Bipolar depression: best practices for the hospitalized patient. CNS spectrums\| PubMed ID: 17984859	2007
Defining the clinical course of bipolar disorder: response, remission, relapse, recurrence, and roughening. Psychopharmacology bulletin\| PubMed ID: 18007564	2007
Incidence of childhood-onset bipolar illness in the USA and Europe. The British journal of psychiatry : the journal of mental science\| PubMed ID: 18245035	2008
Crossmodal visual input for odor tracking during fly flight. Current biology : CB\| PubMed ID: 18280156	2008
Animal behavior: flying back to front. Current biology : CB\| PubMed ID: 18302921	2008
Are bipolar mood symptoms affected by the phase of the menstrual cycle? Journal of women's health (2002)\| PubMed ID: 18328012	2008
Aripiprazole efficacy in irritability and disruptive-aggressive symptoms: young mania rating scale line analysis from two, randomized, double-blind, placebo-controlled trials. Journal of clinical psychopharmacology\| PubMed ID: 18344741	2008
Flies see second-order motion. Current biology : CB\| PubMed ID: 18522814	2008
Context-dependent olfactory enhancement of optomotor flight control in Drosophila. The Journal of experimental biology\| PubMed ID: 18626082	2008
Diagnostic dilemmas and clinical correlates of mixed states in bipolar disorder. The Journal of clinical psychiatry\| PubMed ID: 18681758	2008
Visual edge orientation shapes free-flight behavior in Drosophila. Fly\| PubMed ID: 18820449	2007
Correlates of treatment-emergent mania associated with antidepressant treatment in bipolar depression. The American journal of psychiatry\| PubMed ID: 19015231	2009
The psychometric validation of the Sheehan Disability Scale (SDS) in patients with bipolar disorder. Psychiatry research\| PubMed ID: 19042030	2009
The neuro-ecology of resource localization in Drosophila: behavioral components of perception and search. Fly\| PubMed ID: 19218831	2009
Invertebrate solutions for sensing gravity. Current biology : CB\| PubMed ID: 19278626	2009
Peripheral visual circuits functionally segregate motion and phototaxis behaviors in the fly. Current biology : CB\| PubMed ID: 19303299	2009
Impact of antidepressant continuation after acute positive or partial treatment response for bipolar depression: a blinded, randomized study. The Journal of clinical psychiatry\| PubMed ID: 19358785	2009
Disrupting disordered neurocircuitry: treating refractory psychiatric illness with neuromodulation. Mayo Clinic proceedings. Mayo Clinic\| PubMed ID: 19483169	2009
Flies require bilateral sensory input to track odor gradients in flight. Current biology : CB\| PubMed ID: 19576769	2009
Mood stabilization and destabilization during acute and continuation phase treatment for bipolar I disorder with lamotrigine or placebo. The Journal of clinical psychiatry\| PubMed ID: 19689918	2009
Olanzapine/fluoxetine combination for the treatment of mixed depression in bipolar I disorder: a post hoc analysis. The Journal of clinical psychiatry\| PubMed ID: 19906346	2009
Visual stabilization dynamics are enhanced by standing flight velocity. Biology letters\| PubMed ID: 19955168	2010
Neurobiology: fly gyro-vision. Current biology : CB\| PubMed ID: 20064422	2009
Modafinil for bipolar depression with comorbid methamphetamine abuse. The American journal on addictions / American Academy of Psychiatrists in Alcoholism and Addictions\| PubMed ID: 20163392	2010
Multisensory systems integration for high-performance motor control in flies. Current opinion in neurobiology\| PubMed ID: 20202821	2010
Gender and depressive symptoms in 711 patients with bipolar disorder evaluated prospectively in the Stanley Foundation bipolar treatment outcome network. The American journal of psychiatry\| PubMed ID: 20231325	2010
Dynamics of optomotor responses in Drosophila to perturbations in optic flow. The Journal of experimental biology\| PubMed ID: 20348349	2010
Mechanisms of odor-tracking: multiple sensors for enhanced perception and behavior. Frontiers in cellular neuroscience\| PubMed ID: 20407585	2010
Mutation of the Drosophila vesicular GABA transporter disrupts visual figure detection. The Journal of experimental biology\| PubMed ID: 20435823	2010
Improving the design of maintenance studies for bipolar disorder. Current medical research and opinion\| PubMed ID: 20515320	2010
Multisensory integration for odor tracking by flying Drosophila: Behavior, circuits and speculation. Communicative & integrative biology\| PubMed ID: 20539786	2010
Gender differences in the relationship between depressive symptoms and cravings in alcoholism. The American journal on addictions / American Academy of Psychiatrists in Alcoholism and Addictions\| PubMed ID: 20653643	2010
Early-onset bipolar disorder and treatment delay are risk factors for poor outcome in adulthood. The Journal of clinical psychiatry\| PubMed ID: 20667291	2010
Adjunctive armodafinil for major depressive episodes associated with bipolar I disorder: a randomized, multicenter, double-blind, placebo-controlled, proof-of-concept study. The Journal of clinical psychiatry\| PubMed ID: 20673554	2010
Prevalence and correlates of eating disorders in 875 patients with bipolar disorder. Journal of affective disorders\| PubMed ID: 20674033	2011
Theta motion processing in fruit flies. Frontiers in behavioral neuroscience\| PubMed ID: 20700393	2010
Increased suicidality in mania complicated by alcoholism. Psychiatry (Edgmont (Pa. : Township))\| PubMed ID: 20711326	2007
Complexity of pharmacologic treatment required for sustained improvement in outpatients with bipolar disorder. The Journal of clinical psychiatry\| PubMed ID: 20923622	2010
Utilization of residential alcoholism treatment in bipolar disorder. The American journal on addictions / American Academy of Psychiatrists in Alcoholism and Addictions\| PubMed ID: 21175919	2011
Differential clinical characteristics, medication usage, and treatment response of bipolar disorder in the US versus The Netherlands and Germany. International clinical psychopharmacology\| PubMed ID: 21178634	2011
Clinical practice. Bipolar disorder--a focus on depression. The New England journal of medicine\| PubMed ID: 21208108	2011
Voltage-dependent mania after subthalamic nucleus deep brain stimulation in Parkinson's disease: a case report. Biological psychiatry\| PubMed ID: 21414603	2011
Pharmacogenomics of antidepressant induced mania: a review and meta-analysis of the serotonin transporter gene (5HTTLPR) association. Journal of affective disorders\| PubMed ID: 21680025	2012
Odor identity influences tracking of temporally patterned plumes in Drosophila. BMC neuroscience\| PubMed ID: 21708035	2011
Direct costs of bipolar disorder versus other chronic conditions: an employer-based health plan analysis. Psychiatric services (Washington, D.C.)\| PubMed ID: 21885587	2011
Review of pharmacological treatment in mood disorders and future directions for drug development. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology\| PubMed ID: 21900884	2012
Differences in demographic composition and in work, social, and functional limitations among the populations with unipolar depression and bipolar disorder: results from a nationally represen... Health and quality of life outcomes\| PubMed ID: 21995725	2011
Trazodone and alcohol relapse: a retrospective study following residential treatment. The American journal on addictions / American Academy of Psychiatrists in Alcoholism and Addictions\| PubMed ID: 21999497	2011
An olfactory circuit increases the fidelity of visual behavior. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 22016537	2011
International consensus group on depression prevention in bipolar disorder. The Journal of clinical psychiatry\| PubMed ID: 22075097	2011
Valproate-induced hyperammonemic encephalopathy: an update on risk factors, clinical correlates and management. General hospital psychiatry\| PubMed ID: 22305367	2012