Brent Segelke

Physical and Life Sciences Directorate, Lawrence Livermore National Laboratory

Affiliated withLawrence Livermore National Laboratory Lawrence Livermore National Laboratory

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title Cited by 3	2022

Other Publications

Article	Year
Structural basis for abrogated binding between staphylococcal enterotoxin A superantigen vaccine and MHC-IIalpha. Protein science : a publication of the Protein Society\| PubMed ID: 11847286	2002
The TB structural genomics consortium crystallization facility: towards automation from protein to electron density. Acta crystallographica. Section D, Biological crystallography\| PubMed ID: 12351851	2002
The high-speed Hydra-Plus-One system for automated high-throughput protein crystallography. Acta crystallographica. Section D, Biological crystallography\| PubMed ID: 12351853	2002
Crystal structure of Clostridium botulinum neurotoxin protease in a product-bound state: Evidence for noncanonical zinc protease activity. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 15107500	2004
Laboratory scale structural genomics. Journal of structural and functional genomics\| PubMed ID: 15263853	2004
Macromolecular crystallization with microfluidic free-interface diffusion. Expert review of proteomics\| PubMed ID: 15892562	2005
Structure of Mycobacterium tuberculosis RuvA, a protein involved in recombination. Acta crystallographica. Section F, Structural biology and crystallization communications\| PubMed ID: 16880543	2006
Different apolipoproteins impact nanolipoprotein particle formation. Journal of the American Chemical Society\| PubMed ID: 17963384	2007
Quantifying size distributions of nanolipoprotein particles with single-particle analysis and molecular dynamic simulations. Journal of lipid research\| PubMed ID: 18403317	2008
Cell-free co-expression of functional membrane proteins and apolipoprotein, forming soluble nanolipoprotein particles. Molecular & cellular proteomics : MCP\| PubMed ID: 18603642	2008
Cell-free expression for nanolipoprotein particles: building a high-throughput membrane protein solubility platform. Methods in molecular biology (Clifton, N.J.)\| PubMed ID: 18988032	2009
Atomic force microscopy differentiates discrete size distributions between membrane protein containing and empty nanolipoprotein particles. Biochimica et biophysica acta\| PubMed ID: 19109924	2009
Immobilization of His-tagged proteins on nickel-chelating nanolipoprotein particles. Bioconjugate chemistry\| PubMed ID: 19239247	2009
Characterization and purification of polydisperse reconstituted lipoproteins and nanolipoprotein particles. International journal of molecular sciences\| PubMed ID: 19742178	2009
Amino acid and structural variability of Yersinia pestis LcrV protein. Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases\| PubMed ID: 19835996	2010
An extracellular disulfide bond forming protein (DsbF) from Mycobacterium tuberculosis: structural, biochemical, and gene expression analysis. Journal of molecular biology\| PubMed ID: 20060836	2010
Structure of Rv1848 (UreA), the Mycobacterium tuberculosis urease gamma subunit. Acta crystallographica. Section F, Structural biology and crystallization communications\| PubMed ID: 20606272	2010
Isolation, characterization, and stability of discretely-sized nanolipoprotein particles assembled with apolipophorin-III. PloS one\| PubMed ID: 20657844	2010
Practical applications of structural genomics technologies for mutagen research. Mutation research\| PubMed ID: 21182983	2011
7 Å resolution in protein two-dimensional-crystal X-ray diffraction at Linac Coherent Light Source. Philosophical transactions of the Royal Society of London. Series B, Biological sciences\| PubMed ID: 24914166	2014
Femtosecond X-ray diffraction from two-dimensional protein crystals. IUCrJ\| PubMed ID: 25075325	2014
Fixed-target protein serial microcrystallography with an x-ray free electron laser. Scientific reports\| PubMed ID: 25113598	2014
Structure and function of REP34 implicates carboxypeptidase activity in Francisella tularensis host cell invasion. The Journal of biological chemistry\| PubMed ID: 25231992	2014
Expression and Association of the Yersinia pestis Translocon Proteins, YopB and YopD, Are Facilitated by Nanolipoprotein Particles. PloS one\| PubMed ID: 27015536	2016
Resolution extension by image summing in serial femtosecond crystallography of two-dimensional membrane-protein crystals. IUCrJ\| PubMed ID: 29354276	2018
Proteomic Profiling of During Host Infection Using Bio-Orthogonal Noncanonical Amino Acid Tagging (BONCAT). Frontiers in cellular and infection microbiology\| PubMed ID: 30406044	2018
Discovery of Small-Molecule Inhibitors of SARS-CoV-2 Proteins Using a Computational and Experimental Pipeline. Frontiers in molecular biosciences\| PubMed ID: 34327214	2021
Shotgun Immunoproteomic Approach for the Discovery of Linear B-Cell Epitopes in Biothreat Agents and . Frontiers in immunology\| PubMed ID: 34659206	2021
Functional Annotation from Structural Homology. Methods in molecular biology (Clifton, N.J.)\| PubMed ID: 34718998	2022