sterile-pericarditis-aachener-minipigs-as-model-for-atrial-myopathy

Sterile Pericarditis in Aachener Minipigs As a Model for Atrial Myopathy and Atrial Fibrillation

Atrial fibrillation (AF) is the most common arrhythmia caused by structural remodeling of the atria, also called atrial myopathy. Current therapies only ...

University Hospital Antwerp

Aneurysms affecting the aorta are a common condition associated with high mortality as a result of aortic dissection or rupture. Investigations of the pathogenic mechanisms involved in syndromic types of thoracic aortic aneurysms, such as Marfan and Loeys-Dietz syndromes, have revealed an important contribution of disturbed transforming growth factor (TGF)-β signaling.

Mutations in a TGF-β ligand, TGFB3, cause syndromic aortic aneurysms and dissections.

Acute contained rupture of DeBakey type II aortic dissection.

Acute Stanford type A aortic dissection (TAAD) is a life-threatening condition. Surgery is usually performed as a salvage procedure and is associated with significant postoperative early mortality and morbidity. Understanding the patient's conditions and treatment strategies which are associated with these adverse events is essential for an appropriate management of acute TAAD.

Article	Year
Mutations in a TGF-β ligand, TGFB3, cause syndromic aortic aneurysms and dissections. Journal of the American College of Cardiology\| PubMed ID: 25835445	2015
Acute contained rupture of DeBakey type II aortic dissection. Kardiologia polska\| PubMed ID: 32347085	2020
European registry of type A aortic dissection (ERTAAD) - rationale, design and definition criteria. Journal of cardiothoracic surgery\| PubMed ID: 34112230	2021
Correction to: European registry of type A aortic dissection (ERTAAD) - rationale, design and definition criteria. Journal of cardiothoracic surgery\| PubMed ID: 34365965	2021

Steven Laga

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