Ajay P. Singh

Mitchell Cancer Institute, University of South Alabama

Affiliated withUniversity of South Alabama

Research Area

Biography

Ajay P. Singh has not added Biography.
If you are Ajay P. Singh and would like to personalize this page please email our Author Liaison for assistance.

JoVE Journal Publications

ArticleTotal : 1	Year
Publication title Cited by 7	2022

Other Publications

Article	Year
CXCL8 and its cognate receptors in melanoma progression and metastasis. Future oncology (London, England)\| PubMed ID: 20021212	2010
MicroRNA-based Cancer Therapeutics: Big Hope from Small RNAs. Molecular and cellular pharmacology\| PubMed ID: 21289871	2010
Modulation of protein phosphatase 2A activity alters androgen-independent growth of prostate cancer cells: therapeutic implications. Molecular cancer therapeutics\| PubMed ID: 21393425	2011
Honokiol arrests cell cycle, induces apoptosis, and potentiates the cytotoxic effect of gemcitabine in human pancreatic cancer cells. PloS one\| PubMed ID: 21720559	2011
CXCR1 and CXCR2 silencing modulates CXCL8-dependent endothelial cell proliferation, migration and capillary-like structure formation. Microvascular research\| PubMed ID: 21749879	2011
MicroRNA-150 directly targets MUC4 and suppresses growth and malignant behavior of pancreatic cancer cells. Carcinogenesis\| PubMed ID: 21983127	2011
Myb overexpression overrides androgen depletion-induced cell cycle arrest and apoptosis in prostate cancer cells, and confers aggressive malignant traits: potential role in castration resist... Carcinogenesis\| PubMed ID: 22431717	2012
Honokiol: a novel natural agent for cancer prevention and therapy. Current molecular medicine\| PubMed ID: 22834827	2012
CXCL12/CXCR4 protein signaling axis induces sonic hedgehog expression in pancreatic cancer cells via extracellular regulated kinase- and Akt kinase-mediated activation of nuclear factor κB: ... The Journal of biological chemistry\| PubMed ID: 22995914	2012
An undesired effect of chemotherapy: gemcitabine promotes pancreatic cancer cell invasiveness through reactive oxygen species-dependent, nuclear factor κB- and hypoxia-inducible factor 1α-me... The Journal of biological chemistry\| PubMed ID: 23740244	2013
Cancer "stemness"- regulating microRNAs: role, mechanisms and therapeutic potential. Current drug targets\| PubMed ID: 23834145	2013
MicroRNAs in pancreatic malignancy: progress and promises. Cancer letters\| PubMed ID: 24561061	2014
Synthesis, characterization, and evaluation of poly (D,L-lactide-co-glycolide)-based nanoformulation of miRNA-150: potential implications for pancreatic cancer therapy. International journal of nanomedicine\| PubMed ID: 24971005	2014
p-21 activated kinase 4 promotes proliferation and survival of pancreatic cancer cells through AKT- and ERK-dependent activation of NF-κB pathway. Oncotarget\| PubMed ID: 25238288	2014
CXCL12/CXCR4 signaling counteracts docetaxel-induced microtubule stabilization via p21-activated kinase 4-dependent activation of LIM domain kinase 1. Oncotarget\| PubMed ID: 25359780	2014
Silver nanoparticles protect human keratinocytes against UVB radiation-induced DNA damage and apoptosis: potential for prevention of skin carcinogenesis. Nanomedicine : nanotechnology, biology, and medicine\| PubMed ID: 25804413	2015
Modulation of microRNAs by phytochemicals in cancer: underlying mechanisms and translational significance. BioMed research international\| PubMed ID: 25853141	2015
MicroRNAs: emerging novel targets of cancer therapies. BioMed research international\| PubMed ID: 25866788	2015
Resistin and interleukin-6 exhibit racially-disparate expression in breast cancer patients, display molecular association and promote growth and aggressiveness of tumor cells through STAT3 a... Oncotarget\| PubMed ID: 25868978	2015
Gemcitabine triggers angiogenesis-promoting molecular signals in pancreatic cancer cells: Therapeutic implications. Oncotarget\| PubMed ID: 25970774	2015
MicroRNA-345 induces apoptosis in pancreatic cancer cells through potentiation of caspase-dependent and -independent pathways. British journal of cancer\| PubMed ID: 26247574	2015
Development and Characterization of a Novel in vitro Progression Model for UVB-Induced Skin Carcinogenesis. Scientific reports\| PubMed ID: 26349906	2015
Size is an essential parameter in governing the UVB-protective efficacy of silver nanoparticles in human keratinocytes. BMC cancer\| PubMed ID: 26373391	2015
p-21 activated kinase 4 (PAK4) maintains stem cell-like phenotypes in pancreatic cancer cells through activation of STAT3 signaling. Cancer letters\| PubMed ID: 26546043	2016
MYB is a novel regulator of pancreatic tumour growth and metastasis. British journal of cancer\| PubMed ID: 26657649	2015
Pancreatic Cancer Exosomes: Shedding Off for a Meaningful Journey. Pancreatic disorders & therapy\| PubMed ID: 27030812	2016
Molecular Targets of Honokiol: A Promising Phytochemical for Effective Cancer Management. The Enzymes\| PubMed ID: 27102704	2014
MYB Promotes Desmoplasia in Pancreatic Cancer through Direct Transcriptional Up-regulation and Cooperative Action of Sonic Hedgehog and Adrenomedullin. The Journal of biological chemistry\| PubMed ID: 27246849	2016
Deep sequencing and in silico analyses identify MYB-regulated gene networks and signaling pathways in pancreatic cancer. Scientific reports\| PubMed ID: 27354262	2016
Honokiol suppresses pancreatic tumor growth, metastasis and desmoplasia by interfering with tumor-stromal cross-talk. Carcinogenesis\| PubMed ID: 27609457	2016
Comparative analysis of the relative potential of silver, Zinc-oxide and titanium-dioxide nanoparticles against UVB-induced DNA damage for the prevention of skin carcinogenesis. Cancer letters\| PubMed ID: 27693632	2016
Racial disparities in prostate cancer: a molecular perspective. Frontiers in bioscience (Landmark edition)\| PubMed ID: 27814645	2017
Epigenetic basis of cancer health disparities: Looking beyond genetic differences. Biochimica et biophysica acta. Reviews on cancer\| PubMed ID: 28108348	2017
Biological basis of cancer health disparities: resources and challenges for research. American journal of cancer research\| PubMed ID: 28123843	2017
Exosomes confer chemoresistance to pancreatic cancer cells by promoting ROS detoxification and miR-155-mediated suppression of key gemcitabine-metabolising enzyme, DCK. British journal of cancer\| PubMed ID: 28152544	2017
Resistin potentiates chemoresistance and stemness of breast cancer cells: Implications for racially disparate therapeutic outcomes. Cancer letters\| PubMed ID: 28302531	2017
Emerging evidence for the role of differential tumor microenvironment in breast cancer racial disparity: a closer look at the surroundings. Carcinogenesis\| PubMed ID: 28430867	2017
MicroRNAs in gynecological cancers: Small molecules with big implications. Cancer letters\| PubMed ID: 28549791	2017
Exosomal Markers (CD63 and CD9) Expression Pattern Using Immunohistochemistry in Resected Malignant and Nonmalignant Pancreatic Specimens. Pancreas\| PubMed ID: 28609367	2017
Racial health disparities in ovarian cancer: not just black and white. Journal of ovarian research\| PubMed ID: 28931403	2017
ETV4 Facilitates Cell-Cycle Progression in Pancreatic Cells through Transcriptional Regulation of Cyclin D1. Molecular cancer research : MCR\| PubMed ID: 29117940	2018
Germline pharmacogenomics of DPYD*9A (c.85T>C) variant in patients with gastrointestinal malignancies treated with fluoropyrimidines. Journal of gastrointestinal oncology\| PubMed ID: 29998006	2018
ETV4: an emerging target in pancreatic cancer. Oncoscience\| PubMed ID: 30460327	2018
Revisiting the Clinical Importance of DPYD*9A (c.85T>C) Variant of Dihydropyrimidine Dehydrogenase (DPYD) Gene in Patients Treated with Fluoropyrimidine-Based Chemotherapy. Journal of molecular biomarkers & diagnosis\| PubMed ID: 31105991	2018
The Prevalence of DPYD*9A(c.85T>C) Genotype and the Genotype-Phenotype Correlation in Patients with Gastrointestinal Malignancies Treated With Fluoropyrimidines: Updated Analysis. Clinical colorectal cancer\| PubMed ID: 31160238	2019
Exosomal markers (CD63 and CD9) expression and their prognostic significance using immunohistochemistry in patients with pancreatic ductal adenocarcinoma. Journal of gastrointestinal oncology\| PubMed ID: 31392050	2019
Hypoxia alters the release and size distribution of extracellular vesicles in pancreatic cancer cells to support their adaptive survival. Journal of cellular biochemistry\| PubMed ID: 31407387	2020
Modulation of the tumor microenvironment by natural agents: implications for cancer prevention and therapy. Seminars in cancer biology\| PubMed ID: 32470379	2020
Epidermal growth factor receptor-activating mutation(E746_T751>VP) in pancreatic ductal adenocarcinoma responds to erlotinib, followed by epidermal growth factor receptor resistance-mediatin... Journal of cancer research and therapeutics\| PubMed ID: 32930150	2020
The prevalence and clinical relevance of 2R/2R TYMS genotype in patients with gastrointestinal malignancies treated with fluoropyrimidine-based chemotherapy regimens. The pharmacogenomics journal\| PubMed ID: 33608662	2021
Clinicopathologic significance and race-specific prognostic association of MYB overexpression in ovarian cancer. Scientific reports\| PubMed ID: 34145334	2021
The impact of neoadjuvant concurrent chemoradiation on exosomal markers (CD63 and CD9) expression and their prognostic significance in patients with rectal adenocarcinoma. Oncotarget\| PubMed ID: 34316329	2021
Platinum-resistant ovarian cancer: From drug resistance mechanisms to liquid biopsy-based biomarkers for disease management. Seminars in cancer biology\| PubMed ID: 34418576	2021
MYB interacts with androgen receptor, sustains its ligand-independent activation and promotes castration resistance in prostate cancer. British journal of cancer\| PubMed ID: 34837075	2021
Determining the Size Distribution and Integrity of Extracellular Vesicles by Dynamic Light Scattering. Methods in molecular biology (Clifton, N.J.)\| PubMed ID: 35044664	2022