Leo Q. Wan

Leo Q. Wan

Department of Biomedical Engineering, Rensselaer Polytechnic Institute

Affiliated withRensselaer Polytechnic Institute

Research Area

Biography

Dr. Leo Q. Wan is an associate professor in the Department of Biomedical Engineering at the Rensselaer Polytechnic Institute in Troy, NY. His research focuses on understanding physical biology in tissue development and regeneration and includes Tissue Morphogenesis, Stem Cell Mechanobiology, and Functional Tissue Engineering. He is a pioneer in cell chirality research with bioengineering platforms. His lecture titled “Why are human bodies asymmetrical?”, collaborated with TED-Ed, has over 1 million views. Dr. Wan received his Bachelor’s degree in Mechanics and Mechanical Engineering and his Master's degree in Fluid Mechanics from the University of Science and Technology of China. After completing his Ph.D. in Biomedical Engineering at Columbia University in 2007, he became a postdoctoral scientist in the area of Stem Cells and Tissue Engineering. Leo is a Pew scholar (Class 2013), and a recipient of the NIH Director’s New Innovator Award, National Science Foundation Early Career Award, American Heart Association Scientist Development Grant, and the March of Dimes Basil O’Connor Starter Scholar Research Award. He is a fellow of the American Heart Association (FAHA).

JoVE Journal Publications

ArticleTotal : 1
Year
A Micropatterning Assay for Measuring Cell Chirality
Publication title

Cited by 4

2022

Other Publications

Article
Year
Micropatterning of cells reveals chiral morphogenesis.

Stem cell research & therapy| PubMed ID: 23672821

2013
2014
High-throughput cell aggregate culture for stem cell chondrogenesis.

Methods in molecular biology (Clifton, N.J.)| PubMed ID: 24676785

2014
Large, stratified, and mechanically functional human cartilage grown in vitro by mesenchymal condensation.

Proceedings of the National Academy of Sciences of the United States of America| PubMed ID: 24778247

2014
2015
2015
Inhibition of cell-cell adhesion impairs directional epithelial migration on micropatterned surfaces.

Integrative biology : quantitative biosciences from nano to macro| PubMed ID: 25923643

2015
2016
2016
2016
2016
Cell chirality: emergence of asymmetry from cell culture.

Philosophical transactions of the Royal Society of London. Series B, Biological sciences| PubMed ID: 27821525

2016
Multiaxial Polarity Determines Individual Cellular and Nuclear Chirality.

Cellular and molecular bioengineering| PubMed ID: 28360944

2017
2017
2017
2018
Teratogen screening with human pluripotent stem cells.

Integrative biology : quantitative biosciences from nano to macro| PubMed ID: 30095839

2018
2018
2019
Epithelial Cell Chirality Revealed by Three-Dimensional Spontaneous Rotation.

Proceedings of the National Academy of Sciences of the United States of America| PubMed ID: 30429314

2018
Intrinsic cellular chirality regulates left-right symmetry breaking during cardiac looping.

Proceedings of the National Academy of Sciences of the United States of America| PubMed ID: 30459275

2018
In Vitro Microscale Models for Embryogenesis.

Advanced biosystems| PubMed ID: 30533517

2018
2018
2019
Cell organelle-based analysis of cell chirality.

Communicative & integrative biology| PubMed ID: 31143366

2019
Cardiomyocyte orientation modulated by the Numb family proteins-N-cadherin axis is essential for ventricular wall morphogenesis.

Proceedings of the National Academy of Sciences of the United States of America| PubMed ID: 31300538

2019
Cell chirality in cardiovascular development and disease.

APL bioengineering| PubMed ID: 32903894

2020
2021
2021
2021
Cell Chirality as a Novel Measure for Cytotoxicity.

Advanced biology| PubMed ID: 34796704

2022