modeling-an-enzyme-active-site-using-molecular-visualization-freeware

Modeling an Enzyme Active Site using Molecular Visualization Freeware

Biomolecular visualization skills are paramount to understanding key concepts in the biological sciences, such as structure-function relationships and ...

The University of Texas at Austin

The synthesis of a thiomethyl analogue of 5-hydroxyaloin A has been achieved using benzyne and naphthyne [4 + 2] cycloadditions with substituted furans. A regiocontrolled cycloaddition was achieved using a silicon tether, and a regioselective ring opening was accomplished using a sulfide as a directing group.

Approach toward the total synthesis of 5-hydroxyaloin A.

While molecular visualization has been recognized as a threshold concept in biology education, the explicit assessment of students' visual literacy skills is rare. To facilitate the evaluation of this fundamental ability, a series of NSF-IUSE-sponsored workshops brought together a community of faculty engaged in creating instruments to assess students' biomolecular visualization skills. These efforts expanded our earlier work in which we created a rubric describing overarching themes, learning goals, and learning objectives that address student progress toward biomolecular visual literacy. Here, the BioMolViz Steering Committee (BioMolViz.org) documents the results of those workshops and uses social network analysis to examine the growth of a community of practice. We also share many of the lessons we learned as our workshops evolved, as they may be instructive to other members of the scientific community as they organize workshops of their own.

Article	Year
Approach toward the total synthesis of 5-hydroxyaloin A. Organic letters\| PubMed ID: 21082813	2010
Meeting report: BioMolViz workshops for developing assessments of biomolecular visual literacy. Biochemistry and molecular biology education : a bimonthly publication of the International Union of Biochemistry and Molecular Biology\| PubMed ID: 32914931	2021

Kristen Procko

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