Kensei Taguchi

Kensei Taguchi

Division of Nephrology and Hypertension, Vanderbilt University Medical Center

Affiliated withVanderbilt University Medical Center

Research Area

Biography

Dr. Kensei Taguchi is a postdoctoral research fellow in Division of Nephrology and Hypertension, Vanderbilt University Medical Center in Nashville, Tennessee. He received a M.D. degree from Kurume University School of Medicine of Japan in 2006 and a Ph.D. from Kurume University Graduate school.

During his clinical practice, Dr. Taguchi saw many of the patients develop complications due to dialysis and felt there had to be a better solution. Then, he started pursing a PhD with the hopes of finding new treatment options that can be translated from bench to bedside. While he was in graduate school, he studied the pathological role of receptor for advanced glycation endproducts (RAGE) in diabetic and hypertensive nephropathy. He also created DNA aptamer directed against RAGE which can block the interaction of ligands and RAGE and confirmed its inhibitory efficacy. During a postdoctoral training in Vanderbilt, Nashville, Tennessee, he utilized super resolution microscopy to investigate the morphological changes of mitochondrial following kidney injury. In addition, he has been engaged in investigating the mechanism of how acute kidney injury predisposes patients to chronic injury. Dr. Taguchi received a research fund from American Heart Association (2020-2021).

JoVE Journal Publications

ArticleTotal : 1
Year
Identification of the Source of Secreted Proteins in the Kidney by Brefeldin A Injection
Publication title

Cited by 3

2021

Other Publications

Article
Year
RAGE-aptamer attenuates deoxycorticosterone acetate/salt-induced renal injury in mice.

Scientific reports| PubMed ID: 29422652

2018
2019
2019
2019
Proximal tubule ATR regulates DNA repair to prevent maladaptive renal injury responses.

The Journal of clinical investigation| PubMed ID: 31589169

2019
Uremic Toxin-Targeting as a Therapeutic Strategy for Preventing Cardiorenal Syndrome.

Circulation journal : official journal of the Japanese Circulation Society| PubMed ID: 31827008

2019
2021
Dual disruption of eNOS and ApoE gene accelerates kidney fibrosis and senescence after injury.

Biochemical and biophysical research communications| PubMed ID: 33845306

2021
2021