Martin Schmelz

Department of Anaesthesiology, University of Mannheim

Affiliated withUniversity of Mannheim University of Heidelberg University of Mannheim

Research Area

Biography

Martin Schmelz has not added Biography.
If you are Martin Schmelz and would like to personalize this page please email our Author Liaison for assistance.

JoVE Journal Publications

ArticleTotal : 1	Year
Publication title Cited by 3	2008

Other Publications

Article	Year
Interleukin-6 in combination with its soluble IL-6 receptor sensitises rat skin nociceptors to heat, in vivo. Pain\| PubMed ID: 11932061	2002
Prostaglandin E2 induces vasodilation and pruritus, but no protein extravasation in atopic dermatitis and controls. Journal of the American Academy of Dermatology\| PubMed ID: 12077577	2002
ATP responses in human C nociceptors. Pain\| PubMed ID: 12098617	2002
Sensitivity of human scalp skin to pruritic stimuli investigated by intradermal microdialysis in vivo. Journal of the American Academy of Dermatology\| PubMed ID: 12140471	2002
Neural signal processing: the underestimated contribution of peripheral human C-fibers. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 12151549	2002
Pathological C-fibres in patients with a chronic painful condition. Brain : a journal of neurology\| PubMed ID: 12566278	2003
Itch. Lancet\| PubMed ID: 12606187	2003
The effect of the nitric oxide synthase inhibitor N-nitro-L-arginine-methyl ester on neuropeptide-induced vasodilation and protein extravasation in human skin. Journal of vascular research\| PubMed ID: 12808346	2003
Differential modulation of remifentanil-induced analgesia and postinfusion hyperalgesia by S-ketamine and clonidine in humans. Anesthesiology\| PubMed ID: 12826855	2003
Central origin of secondary mechanical hyperalgesia. Journal of neurophysiology\| PubMed ID: 12843313	2003
Proteinase-activated receptor-2 mediates itch: a novel pathway for pruritus in human skin. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 12867500	2003
Substance-P-induced protein extravasation is bilaterally increased in complex regional pain syndrome. Experimental neurology\| PubMed ID: 12957502	2003
Proinflammatory role of proteinase-activated receptor-2 in humans and mice during cutaneous inflammation in vivo. FASEB journal : official publication of the Federation of American Societies for Experimental Biology\| PubMed ID: 14519665	2003
Short-term infusion of the mu-opioid agonist remifentanil in humans causes hyperalgesia during withdrawal. Pain\| PubMed ID: 14581110	2003
Naloxone provokes similar pain facilitation as observed after short-term infusion of remifentanil in humans. Pain\| PubMed ID: 14581115	2003
Neuronal sensitization for histamine-induced itch in lesional skin of patients with atopic dermatitis. Archives of dermatology\| PubMed ID: 14623705	2003
Neurophysiology of pruritus: cutaneous elicitation of itch. Archives of dermatology\| PubMed ID: 14623706	2003
Neurophysiology of pruritus: interaction of itch and pain. Archives of dermatology\| PubMed ID: 14623707	2003
Modern aspects of cutaneous neurogenic inflammation. Archives of dermatology\| PubMed ID: 14623709	2003
No alpha-adrenoreceptor-induced C-fiber activation in healthy human skin. Journal of applied physiology (Bethesda, Md. : 1985)\| PubMed ID: 14672966	2004
Effects of gender and level of surgical sympathetic block on vasoconstrictor function. Clinical autonomic research : official journal of the Clinical Autonomic Research Society\| PubMed ID: 14673680	2003
Differential effects of surgical sympathetic block at the T2 and T4 level on vasoconstrictor function. Clinical autonomic research : official journal of the Clinical Autonomic Research Society\| PubMed ID: 14673681	2003
Opioid-induced mast cell activation and vascular responses is not mediated by mu-opioid receptors: an in vivo microdialysis study in human skin. Anesthesia and analgesia\| PubMed ID: 14742371	2004
Electrically stimulated axon reflexes are diminished in diabetic small fiber neuropathies. Diabetes\| PubMed ID: 14988263	2004
Perioperative intravenous lidocaine has preventive effects on postoperative pain and morphine consumption after major abdominal surgery. Anesthesia and analgesia\| PubMed ID: 15041597	2004
High local concentrations and effects on differentiation implicate interleukin-6 as a paracrine regulator. Obesity research\| PubMed ID: 15044662	2004
Facilitated neurogenic inflammation in unaffected limbs of patients with complex regional pain syndrome. Neuroscience letters\| PubMed ID: 15050689	2004
The cyclooxygenase isozyme inhibitors parecoxib and paracetamol reduce central hyperalgesia in humans. Pain\| PubMed ID: 15109518	2004
Mechanically induced axon reflex and hyperalgesia in human UV-B burn are reduced by systemic lidocaine. European journal of pain (London, England)\| PubMed ID: 15109974	2004
Catecholamine release in human skin--a microdialysis study. Experimental neurology\| PubMed ID: 15191805	2004
Neural activation during experimental allodynia: a functional magnetic resonance imaging study. The European journal of neuroscience\| PubMed ID: 15217377	2004
Sensitization to bradykinin B1 and B2 receptor activation in UV-B irradiated human skin. Pain\| PubMed ID: 15275768	2004
Chemically and electrically induced sweating and flare reaction. Autonomic neuroscience : basic & clinical\| PubMed ID: 15331047	2004
The effect of intravenous infusion of adenosine on electrically evoked hyperalgesia in a healthy volunteer model of central sensitization. Anesthesia and analgesia\| PubMed ID: 15333416	2004
Electrically evoked itch in humans. Pain\| PubMed ID: 15621375	2005
Transcutaneous penetration of toluene in rat skin a microdialysis study. Experimental dermatology\| PubMed ID: 15679579	2005
Altered central excitability and analgesic treatment in patients with restless legs syndrome. Brain : a journal of neurology\| PubMed ID: 15900027	2005
Distribution of cannabinoid receptor 1 (CB1) and 2 (CB2) on sensory nerve fibers and adnexal structures in human skin. Journal of dermatological science\| PubMed ID: 15927811	2005
Different profiles of buprenorphine-induced analgesia and antihyperalgesia in a human pain model. Pain\| PubMed ID: 16154698	2005
Activation of naloxone-sensitive and -insensitive inhibitory systems in a human pain model. The journal of pain : official journal of the American Pain Society\| PubMed ID: 16275600	2005
Itch and pain. Dermatologic therapy\| PubMed ID: 16297001	2005
Neurogenic components of trypsin- and thrombin-induced inflammation in rat skin, in vivo. Experimental dermatology\| PubMed ID: 16364032	2006
Angiotensin converting enzyme has an inhibitory role in CGRP metabolism in human skin. Peptides\| PubMed ID: 16406141	2006
Duration of effects of aspirin on platelet function in healthy volunteers: an analysis using the PFA-100. Journal of clinical anesthesia\| PubMed ID: 16517326	2006
Pathophysiology and treatment of pain in joint disease. Advanced drug delivery reviews\| PubMed ID: 16626837	2006
Frontiers in pruritus research: scratching the brain for more effective itch therapy. The Journal of clinical investigation\| PubMed ID: 16670758	2006
Chronic itch and pain--similarities and differences. European journal of pain (London, England)\| PubMed ID: 16678456	2006
Reduction of pulmonary edema by short-acting local anesthetics. Regional anesthesia and pain medicine\| PubMed ID: 16701192	2006
The neurobiology of itch. Nature reviews. Neuroscience\| PubMed ID: 16791143	2006
Delta-9-THC based monotherapy in fibromyalgia patients on experimentally induced pain, axon reflex flare, and pain relief. Current medical research and opinion\| PubMed ID: 16834825	2006
Bradykinin is a potent pruritogen in atopic dermatitis: a switch from pain to itch. Pain\| PubMed ID: 16842920	2006
Neurophysiological, neuroimmunological, and neuroendocrine basis of pruritus. The Journal of investigative dermatology\| PubMed ID: 16845410	2006
Catecholamine-induced excitation of nociceptors in sympathetically maintained pain. Pain\| PubMed ID: 16997471	2007
Modulation of remifentanil-induced analgesia and postinfusion hyperalgesia by parecoxib in humans. Anesthesiology\| PubMed ID: 17065897	2006
Abnormal function of C-fibers in patients with diabetic neuropathy. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 17079656	2006
Potentiation of nociceptive responses to low pH injections in humans by prostaglandin E2. The journal of pain : official journal of the American Pain Society\| PubMed ID: 17337250	2007
Monocyte chemoattractant protein-1 in subcutaneous abdominal adipose tissue: characterization of interstitial concentration and regulation of gene expression by insulin. The Journal of clinical endocrinology and metabolism\| PubMed ID: 17456576	2007
The impact of opioid-induced hyperalgesia for postoperative pain. Best practice & research. Clinical anaesthesiology\| PubMed ID: 17489220	2007
Opioids and the skin: "itchy" perspectives beyond analgesia and abuse. The Journal of investigative dermatology\| PubMed ID: 17502859	2007
Differential sensitivity of thick and thin fibers to HIV and therapy-induced neuropathy. Autonomic neuroscience : basic & clinical\| PubMed ID: 17561445	2007
Rapid flare development evoked by current frequency-dependent stimulation analyzed by full-field laser perfusion imaging. Neuroreport\| PubMed ID: 17589307	2007
Clinical classification of itch: a position paper of the International Forum for the Study of Itch. Acta dermato-venereologica\| PubMed ID: 17598029	2007
Nociceptor sensitization to mechanical and thermal stimuli in pig skin in vivo. European journal of pain (London, England)\| PubMed ID: 17611131	2008
Endothelin 1 activates and sensitizes human C-nociceptors. Pain\| PubMed ID: 17884295	2008
Representation of UV-B-induced thermal and mechanical hyperalgesia in the human brain: a functional MRI study. Human brain mapping\| PubMed ID: 17948883	2008
A subpopulation of capsaicin-sensitive porcine dorsal root ganglion neurons is lacking hyperpolarization-activated cyclic nucleotide-gated channels. European journal of pain (London, England)\| PubMed ID: 18218331	2008
Neuropeptides, neurogenic inflammation and complex regional pain syndrome (CRPS). Neuroscience letters\| PubMed ID: 18423863	2008
Role of TRPM8 and TRPA1 for cold allodynia in patients with cold injury. Pain\| PubMed ID: 18440147	2008
Separate peripheral pathways for pruritus in man. Journal of neurophysiology\| PubMed ID: 18562548	2008
Facilitated neurotrophin release in sensitized human skin. European journal of pain (London, England)\| PubMed ID: 18571954	2009
In situ profiling of adipokines in subcutaneous microdialysates from lean and obese individuals. American journal of physiology. Endocrinology and metabolism\| PubMed ID: 18780773	2008
Chapter 18 Itch and cold allodynia. Handbook of clinical neurology / edited by P.J. Vinken and G.W. Bruyn\| PubMed ID: 18808840	2006
Chapter 29 Microneurography in the assessment of neuropathic pain. Handbook of clinical neurology / edited by P.J. Vinken and G.W. Bruyn\| PubMed ID: 18808851	2006
Painful and nonpainful phantom and stump sensations in acute traumatic amputees. The Journal of trauma\| PubMed ID: 18849803	2008
Itch and pain. Neuroscience and biobehavioral reviews\| PubMed ID: 19146873	2010
Differential endogenous pain modulation in complex-regional pain syndrome. Brain : a journal of neurology\| PubMed ID: 19153154	2009
Neural fractalkine expression is closely linked to pain and pancreatic neuritis in human chronic pancreatitis. Laboratory investigation; a journal of technical methods and pathology\| PubMed ID: 19153557	2009
Translating nociceptive processing into human pain models. Experimental brain research. Experimentelle Hirnforschung. ExpÃ©rimentation cÃ©rÃ©brale\| PubMed ID: 19404625	2009
Post-junctional facilitation of Substance P signaling in a tibia fracture rat model of complex regional pain syndrome type I. Pain\| PubMed ID: 19464118	2009
How pain becomes itch. Pain\| PubMed ID: 19467787	2009
Predominant CB2 receptor expression in endothelial cells of glioblastoma in humans. Brain research bulletin\| PubMed ID: 19480992	2009
Hematopoietic colony-stimulating factors mediate tumor-nerve interactions and bone cancer pain. Nature medicine\| PubMed ID: 19525966	2009
Long-acting local anesthetics attenuate FMLP-induced acute lung injury in rats. Anesthesia and analgesia\| PubMed ID: 19690261	2009
Single-fiber recordings of unmyelinated afferents in pig. Neuroscience letters\| PubMed ID: 19818831	2010
Acute hyperinsulinemia differentially regulates interstitial and circulating adiponectin oligomeric pattern in lean and insulin-resistant, obese individuals. The Journal of clinical endocrinology and metabolism\| PubMed ID: 19820029	2009
Patterns of activity-dependent conduction velocity changes differentiate classes of unmyelinated mechano-insensitive afferents including cold nociceptors, in pig and in human. Pain\| PubMed ID: 19913997	2010
Neurotrophins in the cerebrospinal fluid of patient cohorts with neuropathic pain, nociceptive pain, or normal pressure hydrocephalus. The Clinical journal of pain\| PubMed ID: 19920725	2009
Pain: itch without pain-a labeled line for itch sensation? Nature reviews. Neurology\| PubMed ID: 19953111	2009
NGF induces non-inflammatory localized and lasting mechanical and thermal hypersensitivity in human skin. Pain\| PubMed ID: 20022698	2010
Nerve growth factor-evoked nociceptor sensitization in pig skin in vivo. Journal of neuroscience research\| PubMed ID: 20143422	2010
Thoracoscopic sympathectomy at the T2 or T3 level facilitates bradykinin-induced protein extravasation in human forearm skin. Pain medicine (Malden, Mass.)\| PubMed ID: 20202140	2010
Experimental thermal lesions induce beta-thromboglobulin release from activated platelets. European journal of pain (London, England)\| PubMed ID: 20510637	2011
Pituitary adenylate cyclase activating polypeptide: an important vascular regulator in human skin in vivo. The American journal of pathology\| PubMed ID: 20889562	2010
Electrically induced quantitative sudomotor axon reflex test in human volunteers. Autonomic neuroscience : basic & clinical\| PubMed ID: 20923721	2011
Pathogenesis of pruritus. Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG\| PubMed ID: 21208378	2011
Differential central pain processing following repetitive intramuscular proton/prostaglandin Eâ‚‚ injections in female fibromyalgia patients and healthy controls. European journal of pain (London, England)\| PubMed ID: 21277243	2011
Chimpanzees know that others make inferences. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 21282649	2011
Effects of COX inhibition on experimental pain and hyperalgesia during and after remifentanil infusion in humans. Pain\| PubMed ID: 21396775	2011
Time course of acetylcholine-induced activation of sympathetic efferents matches axon reflex sweating in humans. Journal of the peripheral nervous system : JPNS\| PubMed ID: 21504500	2011
NGF enhances electrically induced pain, but not axon reflex sweating. Pain\| PubMed ID: 21546161	2011
Neuronal sensitivity of the skin. European journal of dermatology : EJD\| PubMed ID: 21628129	2011
Structural and functional differences between neuropathy with and without pain? Experimental neurology\| PubMed ID: 21683699	2011
Nerve growth factor selectively decreases activity-dependent conduction slowing in mechano-insensitive C-nociceptors. Pain\| PubMed ID: 21763072	2011
A study of serum concentrations and dermal levels of NGF in atopic dermatitis and healthy subjects. Neuropeptides\| PubMed ID: 21893340	2011
Does spontaneous activity in C-nociceptors provide a readout to quantify neuropathic pain? Pain\| PubMed ID: 22014531	2012
Double spikes to single electrical stimulation correlates to spontaneous activity of nociceptors in painful neuropathy patients. Pain\| PubMed ID: 22154219	2012